Patents by Inventor Jigar Patel

Jigar Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240171943
    Abstract: Embodiments of a method and non-transitory computer readable mediums for vehicle data collection are disclosed. In an embodiment, the method for vehicle data collection includes receiving, at a cloud computing system, vehicle data that indicates a location of a vehicle and a data reporting mode of the vehicle, determining, by the cloud computing system, whether the vehicle is located in an alerting zone using the vehicle data, determining, by the cloud computing system, if the data reporting mode of the vehicle needs to be changed based on the alerting zone determination, and generating, by the cloud computing system, a policy message for transmission to the vehicle when the data reporting mode needs to be changed, where the policy message indicates an updated data reporting mode of the vehicle.
    Type: Application
    Filed: November 18, 2022
    Publication date: May 23, 2024
    Inventors: Jigar Patel, Cory Hohs
  • Publication number: 20240169832
    Abstract: A method for vehicle alerting includes receiving, at a cloud computing system, digital data that includes a location of a vehicle and a hazard lights on status of the vehicle, determining a functional classification of a road that corresponds to the location of the vehicle, wherein the digital data is received from the vehicle via a wireless connection, and determining whether to initiate an alert messaging operation in response to the functional classification of the road and the hazard lights on status, wherein determining whether to initiate the alert messaging operation involves selecting from available options of 1) initiating the alert messaging operation when the functional classification of the road is determined to be within a first set of functional classifications, and 2) not initiating the alert messaging operation when the functional classification of the road is determined to be within a second set of functional classifications.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 23, 2024
    Inventors: Jigar Patel, Cory Hohs, Jeremy Agulnek
  • Publication number: 20240132509
    Abstract: Disclosed are quinoline and quinazoline compounds which modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and genitourinary system. Preferred compounds include quinoline or quinazoline derivatives substituted at the 4-position via N(H), C(O) or O moieties.
    Type: Application
    Filed: November 13, 2023
    Publication date: April 25, 2024
    Inventors: Nadiya Sydorenko, Md Rauful Alam, Michael A. Arnold, Suresh Babu, Anuradha Bhattacharyya, Guangming Chen, Aleksey I. Gerasyuto, Gary Mitchell Karp, Andrew J. Kassick, Anthony R. Mazzotti, Young-Choon Moon, Jana Narasimhan, Jigar Patel, Anthony Turpoff, Matthew G. Woll, Wuming Yan, Nanjing Zhang
  • Patent number: 11858941
    Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: January 2, 2024
    Assignee: PTC THERAPEUTICS, INC.
    Inventors: Nadiya Sydorenko, Md Rauful Alam, Michael A. Arnold, Suresh Babu, Anuradha Bhattacharyya, Guangming Chen, Aleksey I. Gerasyuto, Gary Mitchell Karp, Andrew J. Kassick, Anthony R. Mazzotti, Young-Choon Moon, Jana Narasimhan, Jigar Patel, Anthony Turpoff, Matthew G. Woll, Wuming Yan, Nanjing Zhang
  • Patent number: 11813371
    Abstract: A currency disinfecting assembly for sterilizing paper currency includes a cabinet that is comprised of an opaque material to inhibit light from passing therethrough. A plurality of holders is each disposed in an interior of the cabinet to accommodate paper currency. A plurality of light emitters is each coupled to the cabinet to emit light outwardly therefrom. Each of the light emitters is positioned inside of the cabinet to direct the light onto the paper currency. Moreover, each of the light emitters emits light in the ultraviolet spectrum to sterilize the paper currency.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: November 14, 2023
    Inventor: Jigar Patel
  • Publication number: 20230298765
    Abstract: A computer-implemented process receives unstructured patient data pertaining to a patient. Furthermore, the computer-implemented process eliminates redundant words from the unstructured patient data. Additionally, the computer-implemented process generates a numerical representation of the unstructured patient data and a context-specific textual representation of the unstructured patient data. The computer-implemented process classifies, via the machine learning engine, one or more potential portions of the context-specific textual representation of the unstructured data in a risk stratification category. Additionally, the computer-implemented process determines that one or more potential corresponding portions of the numerical representation is also classified in the risk stratification category. Finally, the computer-implemented process outputs, in real-time, an enhancement to the risk stratification category based on the numerical representation also being classified in the risk stratification category.
    Type: Application
    Filed: March 16, 2022
    Publication date: September 21, 2023
    Applicant: Health Advocate Solutions, Inc.
    Inventors: Antonio Legorreta, Mayur Jigar Patel, Janelle Sophia Lewis, Thomas Wiese
  • Publication number: 20230201627
    Abstract: A laser treatment system includes a sensor configured to detect a targeted therapy region. A processing unit is configured to generate a treatment path that consists of sequentially arranged laser spots to enable the treatment path to fully encompass a targeted therapy region to receive laser therapy. A steering device is alerted to move to a plurality of positions based on the treatment plan generated by the processing unit. A treatment laser provides laser therapy to the plurality of positions and targeted therapy region based on the treatment plan generated by the processing unit.
    Type: Application
    Filed: June 18, 2021
    Publication date: June 29, 2023
    Inventors: Jigar PATEL, Weston ROSS, Matthew TUCKER, Guangshen MA, Patrick CODD
  • Patent number: 11670013
    Abstract: Methods, systems, and computing platforms are disclosed. Exemplary implementations may: identify and store anatomical landmarks on a first reference digital image of a region of a human body; insert biopsy site identification data on the first reference digital image with the anatomical landmarks to form a second reference digital image; transform the second reference digital image into a mesh mask image; and overlay the mesh mask image on a third digital image of the region of the human body.
    Type: Grant
    Filed: June 26, 2021
    Date of Patent: June 6, 2023
    Inventors: Jigar Patel, Ayushi Patidar, Parth Patidar
  • Publication number: 20230127514
    Abstract: Disclosed are systems and techniques for providing laser treatment. For example, a vasculature structure associated with a tissue region can be determined. Based on the vasculature structure, one or more laser parameters for configuring a laser to deliver laser energy to at least one blood vessel within the tissue region can be determined. Laser energy can be delivered to the at least one blood vessel to halt blood flow to a targeted area within the tissue region.
    Type: Application
    Filed: December 23, 2022
    Publication date: April 27, 2023
    Inventors: JIGAR PATEL, WESTON ROSS, PATRICK CODD
  • Publication number: 20230119537
    Abstract: The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.
    Type: Application
    Filed: June 17, 2022
    Publication date: April 20, 2023
    Inventors: Peter BRUENKER, Rebecca CROASDALE-WOOD, Christian KLEIN, Juergen Michael SCHANZER, Kay-Gunnar STUBENRAUCH, Pablo UMANA, Martina GEIGER, Eric SULLIVAN, Jigar PATEL
  • Patent number: 11603565
    Abstract: The invention is a method of identifying a cognate antigen for a T-cell receptor using neoantigens from a patient's tumor cells combined with the patient's T-cells and using cell sorting, genome sequencing, expressing TCR genes, presenting tumor neoantigens on MHC complex and uniquely barcoding the T-cells where TCR recognition occurs to tag all components of the TCR recognition complex.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 14, 2023
    Assignees: ROCHE SEQUENCING SOLUTIONS, INC., VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Nelson R. Alexander, Aoune Barhoumi, Jan Berka, Rui Chen, Lisa L. Gallegos, Toumy Guettouche, Seoyoung Kim, Maeve E. O'Huallachain, Sedide Ozturk, Jigar Patel, Florian Rubelt, Stacey Stanislaw
  • Patent number: 11583575
    Abstract: The disclosure provides compositions comprising at least one assembly comprising a peptide and a major histocompatibility complex (MHC), wherein the peptide is an integral component of the MHC, wherein the peptide is attached to a surface at its C-terminus through a linker and wherein the peptide is synthesized on the surface. In certain embodiments, the compositions comprise a plurality of assemblies in a spatially-ordered array. The disclosure provides methods for making and using these compositions.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: February 21, 2023
    Assignees: Roche Sequencing Solutions, Inc., Hoffmann-La Roche Inc.
    Inventors: Christian Klein, Hanying Li, Victor Lyamichev, Ekkehard Moessner, Jigar Patel
  • Publication number: 20230022098
    Abstract: The present invention relates to methods for detecting a target molecule in a liquid sample. The methods described herein comprise applying at least a portion of the liquid sample on a solid substrate that comprises a non-fouling polymer layer, decreasing the atmospheric pressure surrounding the solid substrate containing the portion of the liquid sample for a time sufficient for a majority of the liquid to evaporate from the portion of the liquid sample applied to the solid substrate, contacting the liquid sample with one or more binding agents that binds to the target molecule after the majority of the liquid has evaporated from the liquid sample, and detecting the presence of the one or more binding agents on the solid substrate, wherein the presence of the one or more binding agents indicates the presence of the target molecule in the liquid sample.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 26, 2023
    Inventors: Hui HUANG, Jigar PATEL, Kejalben GHIWALA, Jiacheng YANG
  • Publication number: 20220323622
    Abstract: A currency disinfecting assembly for sterilizing paper currency includes a cabinet that is comprised of an opaque material to inhibit light from passing therethrough. A plurality of holders is each disposed in an interior of the cabinet to accommodate paper currency. A plurality of light emitters is each coupled to the cabinet to emit light outwardly therefrom. Each of the light emitters is positioned inside of the cabinet to direct the light onto the paper currency. Moreover, each of the light emitters emits light in the ultraviolet spectrum to sterilize the paper currency.
    Type: Application
    Filed: April 7, 2021
    Publication date: October 13, 2022
    Inventor: Jigar Patel
  • Publication number: 20220275087
    Abstract: The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.
    Type: Application
    Filed: December 2, 2021
    Publication date: September 1, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Peter BRUENKER, Rebecca CROASDALE-WOOD, Christian KLEIN, Juergen Michael SCHANZER, Kay-Gunnar STUBENRAUCH, Pablo UMANA, Martina GEIGER, Eric SULLIVAN, Jigar PATEL
  • Publication number: 20220251098
    Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
    Type: Application
    Filed: April 18, 2022
    Publication date: August 11, 2022
    Inventors: Matthew G. Woll, Lukiana Amedzo, Suresh Babu, Scott J. Barraza, Anuradha Bhattacharyya, Gary Mitchell Karp, Anthony R. Mazzotti, Jana Narasimhan, Jigar Patel, Anthony Turpoff, Zhenrong Xu
  • Patent number: 11407753
    Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: August 9, 2022
    Assignee: PTC THERAPEUTICS, INC.
    Inventors: Matthew G. Woll, Lukiana Amedzo, Suresh Babu, Scott J. Barraza, Anuradha Bhattacharyya, Gary Mitchell Karp, Anthony R. Mazzotti, Jana Narasimhan, Jigar Patel, Anthony Turpoff, Zhenrong Xu
  • Publication number: 20220243360
    Abstract: The present technology provides an approach to designing libraries of peptide sequences for discovery and testing of significantly more motifs than would be otherwise available in a given fixed library format. The technology includes a plurality of x-mers embedded in N-mer peptides sequences, where N and x are integers and where N is greater than x. This approach provides for the representation of multiple unique x-mer peptides in a single N-mer peptide feature.
    Type: Application
    Filed: June 26, 2020
    Publication date: August 4, 2022
    Inventors: Lauren GOODRICH, Victor LYAMICHEV, Jigar PATEL, Richard PINAPATI, Eric SULLIVAN, Todd RICHMOND
  • Patent number: 11280791
    Abstract: In one aspect, the present disclosure provides a system and method for the identification and characterization of a transglutaminase. Further, the present disclosure provides transglutaminase enzymes for forming isopeptide bonds, methods of forming isopeptide bonds in the presence of transglutaminases, and substrate tags for use with transglutaminases. In another aspect, the present disclosure provides glutamine-containing substrates (or Q-tag substrates) that are more resistant to proteases/clipping and therefore, more stable, than other Q-tag substrates, and their uses in substrate tags for cross-linking to an amine-donor tag via an isopeptide bond mediated by a microbial transglutaminase.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: March 22, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Thomas Albert, Frank Bergmann, Victor Lyamichev, Mohamed Yosry Hassan Mohamed, Tobias Oelschlaegel, Jigar Patel, Michael Schraeml, Wojtek Steffen, Thomas Streidl
  • Patent number: 11268120
    Abstract: According to one aspect, the present disclosure provides a method of identifying a substrate of a transglutaminase using a peptide array comprising a plurality of peptides. The method includes the steps of contacting the peptides in the peptide array with the transglutaminase, allowing the transglutaminase to bind to the peptides, and identifying the substrate of the transglutaminase.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: March 8, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Thomas Albert, Frank Bergmann, Victor Lyamichev, Jigar Patel, Michael Schraeml, Wojtek Steffen