Patents by Inventor Ji-Guang Zhang
Ji-Guang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11965187Abstract: A targeted DNA demethylation method (Mini-CRISD) and a fusion protein used in the method are provided. The Mini-CRISD method can targets delivery of demethylation activity through engineered miniature dCjCas9 to deliver engineered miniature ROS1 demethylation effector to specific DNA sequences and/or specific genomic locations (such as CpG islands) to achieve targeted demethylation of specific DNA.Type: GrantFiled: January 17, 2023Date of Patent: April 23, 2024Assignees: GUANGZHOU MEDICAL UNIVERSITY, GMU NEW DRUG DEVELOPMENT CO., LTD.Inventors: Xi-Yong Yu, Yu-Guang Zhu, Ao Shen, Ling-Min Zhang, Ji-Shuo Chang
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Publication number: 20230378543Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: ApplicationFiled: May 31, 2023Publication date: November 23, 2023Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Patent number: 11705580Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: GrantFiled: November 29, 2021Date of Patent: July 18, 2023Assignee: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Publication number: 20230187697Abstract: Localized superconcentrated electrolytes (LSEs) and electrochemical devices including the LSEs are disclosed. The LSE includes an active salt, a solvent in which the active salt is soluble, and a diluent in which the active salt is insoluble or poorly soluble, wherein the diluent includes a fluorinated orthoformate.Type: ApplicationFiled: February 2, 2023Publication date: June 15, 2023Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Patent number: 11664536Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, or a combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent.Type: GrantFiled: January 8, 2021Date of Patent: May 30, 2023Assignee: Battelle Memorial InstituteInventors: Wu Xu, Ji-Guang Zhang, Hao Jia, Xianhui Zhang, Xia Cao, Sujong Chae, Ran Yi, Qiuyan Li, Won-Jin Kwak, Xiaolin Li
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Patent number: 11600859Abstract: Localized superconcentrated electrolytes (LSEs) and electrochemical devices including the LSEs are disclosed. The LSE includes an active salt, a solvent in which the active salt is soluble, and a diluent in which the active salt is insoluble or poorly soluble, wherein the diluent includes a fluorinated orthoformate.Type: GrantFiled: November 19, 2019Date of Patent: March 7, 2023Assignee: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Publication number: 20220340429Abstract: A method for etching materials in which organic solvents are added to the etching mixture and combined in a mixing arrangement. When agitated organic materials mix with the etching agent and interact with the underlying material to form a shield around the etched areas that prevents the additional interaction of water with the newly etched areas and enables the etching of silicon oxides (SiOx) but does not oxidize Si. This method leads to milder reactions with less heat generation and avoids the safety hazards associated with conventional etching methods.Type: ApplicationFiled: April 27, 2021Publication date: October 27, 2022Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Ran Yi, Ji-Guang Zhang
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Publication number: 20220115706Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: ApplicationFiled: November 29, 2021Publication date: April 14, 2022Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Patent number: 11223036Abstract: An anode active material comprises a silicon-carbon secondary particle comprising a composite having an exterior conformal carbon coating and formed of type I primary particles. Each type I primary particle comprises a core particle of interconnected silicon, the interconnected silicon formed of nano-sized silicon particles each connected to at least one other particle, inner pores internal to the core particle and defined by the interconnected silicon, an internal carbon coating on internal wall surfaces of the inner pores and a conformal carbon coating on the core particle.Type: GrantFiled: November 18, 2019Date of Patent: January 11, 2022Assignee: Apple Inc.Inventors: Zuqin Liu, Richard M. Mank, Hyea Kim, Hongli Dai, Sunho Kang, Ji-Guang Zhang, Ran Yi, Qiuyan Li, Xiaolin Li, Wu Xu, Rajankumar L. Patel, Hyung-Seok Lim, Chongmin Wang, Langli Luo, Yang He
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Patent number: 11127980Abstract: Localized superconcentrated electrolytes (LSEs) for use in systems with silicon-based or carbon/silicon composite-based anodes are disclosed. The LSEs include an active salt, a nonaqueous solvent in which the active salt is soluble, and a diluent in which the active salt has a solubility at least 10 times less than solubility of the active salt in the nonaqueous solvent. Systems including the LSEs also are disclosed.Type: GrantFiled: January 14, 2019Date of Patent: September 21, 2021Assignee: Battelle Memorial InstituteInventors: Ji-Guang Zhang, Haiping Jia, Xiaolin Li, Wu Xu
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Patent number: 11094966Abstract: Disclosed herein are embodiments of an electrolyte that is stable and efficient at high voltages. The electrolyte can be used in combination with certain cathodes that exhibit poor activity at such high voltages with other types of electrolytes and can further be used in combination with a variety of anodes. In some embodiments, the electrolyte can be used in battery systems comprising a lithium cobalt oxide cathode and lithium metal anodes, silicon anodes, silicon/graphite composite anodes, graphite anodes, and the like.Type: GrantFiled: December 21, 2018Date of Patent: August 17, 2021Assignee: Battelle Memorial InstituteInventors: Xiaodi Ren, Wu Xu, Ji-Guang Zhang
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Publication number: 20210229033Abstract: Polyethylenimine coated polymeric beads comprising a polymer that comprises, based on the weight of the polymer, from 25% to 75% by weight of structural units of an acetoacetoxy or acetoacetamide functional monomer, and from 25% to 75% by weight of structural units of a polyvinyl monomer; the polyethylenimine having a number average molecular weight of 300 g/mol or more; the polyethylenimine coated polymeric beads having a specific surface area in the range of from 20 to 400 m2/g; a process of preparing the polyethylenimine coated polymeric beads; a gas filter device comprising the polyethylenimine coated polymeric beads as a filter medium; and a method of removing aldehydes from air containing aldehydes, comprising contacting the air with the polyethylenimine coated polymeric beads.Type: ApplicationFiled: July 4, 2018Publication date: July 29, 2021Applicant: Dow Global Technologies LLCInventors: Ji Guang Zhang, Jian Zou, Hongyu Chen, Shaoguang Feng, Wenbin Yao, Haiying Li, Xuemei Zhai
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Publication number: 20210218062Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, or a combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent.Type: ApplicationFiled: January 8, 2021Publication date: July 15, 2021Applicant: Battelle Memorial InstituteInventors: Wu Xu, Ji-Guang Zhang, Hao Jia, Xianhui Zhang, Xia Cao, Sujong Chae, Ran Yi, Qiuyan Li, Won-Jin Kwak, Xiaolin Li
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Publication number: 20210122641Abstract: Stabilized porous silicon particles are disclosed. The particles include a porous silicon particle comprising a plurality of interconnected silicon nanoparticles and (i) a heterogeneous layer comprising a discontinuous SiC coating that is discontinuous across a portion of pore surfaces and across a portion of an outer surface of the porous silicon particle, and a continuous carbon coating that covers outer surfaces of the discontinuous SiC coating, and remaining portions of the pore surfaces and the outer surface of the porous silicon particle, or (ii) a continuous carbon coating on surfaces of the porous silicon particle, including the outer surface and pore surfaces. Methods of making the stabilized porous silicon particles also are disclosed.Type: ApplicationFiled: May 20, 2020Publication date: April 29, 2021Applicant: Battelle Memorial InstituteInventors: Ji-Guang Zhang, Ran Yi, Qiuyan Li, Sujong Chae, Xiaolin Li, Yaobin Xu, Chongmin Wang
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Patent number: 10854923Abstract: Low flammability and nonflammable localized superconcentrated electrolytes (LSEs) for stable operation of lithium and sodium ion batteries are disclosed. Electrochemical devices including the low flammability and nonflammable LSEs are also disclosed. The low flammability and nonflammable LSEs include an active salt, a solvent comprising a flame retardant compound, wherein the active salt is soluble in the solvent, and a diluent in which the active salt is insoluble or poorly soluble. The LSE may further include a cosolvent, such as a carbonate, a sulfone, a sulfite, a sulfate, a carboxylate, an ether, a nitrogen-containing solvent, or any combination thereof. In certain embodiments, such as when the solvent and diluent are immiscible, the LSE further includes a bridge solvent.Type: GrantFiled: August 31, 2018Date of Patent: December 1, 2020Assignee: Battelle Memorial InstituteInventors: Wu Xu, Shuru Chen, Ji-Guang Zhang, Xia Cao, Haiping Jia, Bin Liu, Xiaodi Ren
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Publication number: 20200161706Abstract: Localized superconcentrated electrolytes (LSEs) and electrochemical devices including the LSEs are disclosed. The LSE includes an active salt, a solvent in which the active salt is soluble, and a diluent in which the active salt is insoluble or poorly soluble, wherein the diluent includes a fluorinated orthoformate.Type: ApplicationFiled: November 19, 2019Publication date: May 21, 2020Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Publication number: 20200161635Abstract: An anode active material comprises a silicon-carbon secondary particle comprising a composite having an exterior conformal carbon coating and formed of type I primary particles. Each type I primary particle comprises a core particle of interconnected silicon, the interconnected silicon formed of nano-sized silicon particles each connected to at least one other particle, inner pores internal to the core particle and defined by the interconnected silicon, an internal carbon coating on internal wall surfaces of the inner pores and a conformal carbon coating on the core particle.Type: ApplicationFiled: November 18, 2019Publication date: May 21, 2020Inventors: Zuqin Liu, Richard M. Mank, Hyea Kim, Hongli Dai, Sunho Kang, Ji-Guang Zhang, Ran Yi, Qiuyan Li, Xiaolin Li, Wu Xu, Rajankumar L. Patel, Hyung-Seok Lim, Chongmin Wang, Langli Luo, Yang He
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Patent number: 10547088Abstract: Embodiments of a method for cycling a rechargeable alkali metal battery with high Coulombic efficiency (CE) are disclosed. A slow charge/rapid discharge protocol is used in conjunction with a concentrated electrolyte to achieve high CE in rechargeable lithium and sodium batteries, include anode-free batteries. In some examples, the CE is ?99.8%.Type: GrantFiled: April 29, 2016Date of Patent: January 28, 2020Assignee: Battelle Memorial InstituteInventors: Ji-Guang Zhang, Brian D. G. Adams, Wu Xu, Jianming Zheng
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Patent number: 10472571Abstract: Low flammability and nonflammable localized superconcentrated electrolytes (LSEs) for stable operation of electrochemical devices, such as rechargeable batteries, supercapacitors, and sensors, are disclosed. Electrochemical devices, such as rechargeable batteries, supercapacitors, and sensors, including the low flammability and nonflammable LSEs are also disclosed. The low flammability and nonflammable LSEs include an active salt, a solvent comprising a flame retardant compound, wherein the active salt is soluble in the solvent, and a diluent in which the active salt is insoluble or poorly soluble. In certain embodiments, such as when the solvent and diluent are immiscible, the LSE further includes a bridge solvent.Type: GrantFiled: October 19, 2017Date of Patent: November 12, 2019Assignee: Battelle Memorial InstituteInventors: Ji-Guang Zhang, Shuru Chen, Wu Xu
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Publication number: 20190252689Abstract: A one-step in-situ electrochemical pre-charging strategy to generate thin protective films simultaneously on the surfaces of both carbon-based air-electrode and metal anode under an inert atmosphere is disclosed. The thin-films are formed from the decomposition of electrolyte during the in-situ electrochemical pre-charging process in an inert environment and can protect both a carbon air-electrode and a metal anode prior to conventional metal-oxygen discharge/charge cycling where reactive reduced oxygen species are formed. Lithium-oxygen cells after such pre-treatment demonstrate significantly extended cycle life which is far more than those without pre-treatment.Type: ApplicationFiled: October 11, 2017Publication date: August 15, 2019Applicant: Battelle Memorial InstituteInventors: Wu Xu, Bin Liu, Ji-Guang Zhang