Patents by Inventor Jih-Pyang Wang

Jih-Pyang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 18?-Glycyrrhetinic acid derivatives and synthetic method thereof
    Patent number: 8969617
    Abstract: The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: March 3, 2015
    Assignee: Kaohsiung Medical University
    Inventors: Chun-Nan Lin, Dravidum Maitraie, Jih-Pyang Wang, Chi-Feng Hung, Huang-Yao Tu, Ya-Ting Liou, Bai-Luh Wei, Shyh-Chyun Yang
  • 18?-glycyrrhetinic acid derivatives and synthetic method thereof
    Patent number: 8329940
    Abstract: The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: December 11, 2012
    Assignee: Kaohsiung Medical University
    Inventors: Chun-Nan Lin, Dravidum Maitraie, Jih-Pyang Wang, Chi-Feng Hung, Huang-Yao Tu, Ya-Ting Liou, Bai-Luh Wei, Shyh-Chyun Yang
  • 18beta-GLYCYRRHETINIC ACID DERIVATIVES AND SYNTHETIC METHOD THEREOF
    Publication number: 20110039922
    Abstract: The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5.
    Type: Application
    Filed: December 30, 2009
    Publication date: February 17, 2011
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Chun-Nan Lin, Dravidum Maitraie, Jih-Pyang Wang, Chi-Feng Hung, Huang-Yao Tu, Ya-Ting Liou, Bai-Luh Wei, Shyh-Chyun Yang
  • Anti-inflammatory and cure for ageing, Alzheimer's disease on phloroglucinol derivatives
    Publication number: 20060205808
    Abstract: The fresh seeds obtained from the fresh fruits of Garcinia subelliptica, were extracted with chloroform at room temperature. The CHCl3 extract was concentrated under reduced pressure to afford a brown residue. This residue was subjected to column chromatography (silica gel) and eluted with appropriate solvent system to give two phloroglucinol derivatives (Compounds 1 and 4). Compound 1 exhibited potent inhibitory effects on the release of ?-glucuronidase and lysozyme from rat neutrophils stimulated with formyl-Met-Leu-Phe(fMLP)/cyto-chalasin B (CB). Compound 1 also exhibited potent inhibitory effect on the superoxide anion generation in rat neutrophils stimulated with fMLP/CB. Compound 4 exhibited potent inhibitory effect on NO production in lipopolysaccharide (LPS)/interferon-? (IFN-?)-activation in N9 cells. These Compounds may be developed as anti-inflammatory, anti-cancer agent, cure for ageing, and Alzheimer's disease treatment drugs.
    Type: Application
    Filed: March 10, 2005
    Publication date: September 14, 2006
    Applicant: Kaohsiung Medical University
    Inventors: Chun-Nan Lin, Jih-Pyang Wang, Jing-Ru Weng
  • Novel chalcone derivatives and pharmaceutical compositions comprising the same
    Publication number: 20040176471
    Abstract: Disclosed herein are novel chalcone derivatives of formulas (I), (II) and (III): 1
    Type: Application
    Filed: March 7, 2003
    Publication date: September 9, 2004
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Chun-Nan Lin, Jih-Pyang Wang
  • Abruquinone derivatives useful in the treatment of inflammation and allergic reactions
    Patent number: 5856352
    Abstract: Disclosed are methods of providing antiinflammatory activity and inhibiting allergic reaction by administering Abruquinones A, B, D, E, or F to a subject in need thereof.
    Type: Grant
    Filed: April 29, 1997
    Date of Patent: January 5, 1999
    Assignee: National Science Council
    Inventors: Sheng-Chu Kuo, Sheng-Chih Chen, Jin-Bin Wu, Che-Hing Teng, Jih-Pyang Wang
  • Abruquinone derivatives and their uses
    Patent number: 5563167
    Abstract: Disclosed are methods of isolation and purification of active constituents from Hsian-ssu-tsu (Abrus precatorius L.), and the therapeutical applications of the purified compounds. From the cloroform fraction of the methanolic extract of the roots of Abrus precatorius L., Abruquinones A, B, D, E, F, which are shown as Compounds I through V, respectively, as follows: ##STR1## were isolated and identified Pharmacological evaluations showed that these compounds possess an activity to inhibit platelet aggregation, as well as antiinflammatory, and antiallergic activities.
    Type: Grant
    Filed: May 3, 1994
    Date of Patent: October 8, 1996
    Assignee: National Science Council
    Inventors: Sheng-Chu Kuo, Sheng-Chih Chen, Jin-Bin Wu, Che-Ming Teng, Jih-Pyang Wang