Abstract: Reagents that regulate human serine/threonine kinase and reagents which bind to human serine/threonine kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, diabetes, neurological disorders, cardiovascular disorders, musculo-skeletal disorders, inflammatory disorders, genitourological disorders, and respiratory disorders (e.g., asthma and COPD).

Abstract: Reagents that regulate human receptor tyrosine kinase MerTK and reagents which bind to human receptor tyrosine kinase MerTK gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, gastrointestinal and liver disorders, cancer, metabolic disorders (particularly diabetes), neurological disorders, cardiovascular disorders (particularly coronary heart disease), hematological disorders, reproductive disorders, endocrine and hormonal disorders, respiratory disorders (particularly COPD), and genitourinary disorders.

Abstract: Reagents that regulate human BMP-2 inducible kinase and reagents which bind to human BMP-2 inducible kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, diabetes, CNS disorders, COPD, gastrointestinal disorders, and cardiovascular disorders.

Abstract: Reagents that regulate human serine/threonine kinase and reagents which bind to human serine/threonine kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, diabetes, neurological disorders, cardiovascular disorders, musculo-skeletal disorders, inflammatory disorders, genitourological disorders, and respiratory disorders (e.g., asthma and COPD).

Abstract: Reagents that regulate human serine/threonine kinase and reagents which bind to human serine/threonine kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, genitouro-logical disorders, peripheral and central nervous system disorders, gastrointestinal disorders, diabetes, cancer, COPD, and asthma.

Abstract: Reagents which regulate human secretin receptor-like GPCR and reagents which bind to human secretin-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, urinary incontinence, benign prostate hyperplasia, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism, neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.

Abstract: Reagents which regulate human secretin receptor-like GPCR and reagents which bind to human secretin-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cardiovascular disorders, urinary incontinence, benign prostate hyperplasia, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.

Abstract: Reagents which regulate human MAP kinase phosphatase-like enzyme and reagents which bind to human MAP kinase phosphatase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, allergies including asthma, CNS disorders, diabetes, obesity, chronic obstructive pulmonary disease, cancer, and cardiovascular diseases.