Patents by Inventor Jije Gu

Jije Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210009681
    Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
    Type: Application
    Filed: February 7, 2020
    Publication date: January 14, 2021
    Applicant: AbbVie Inc.
    Inventors: Ming-Jiu Chen, Chung-Ming Hsieh, Jije Gu, Susan Morgan-Lappe, Yingchun Li
  • Publication number: 20190315855
    Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 17, 2019
    Applicant: AbbVie Inc.
    Inventors: Ming-Jiu Chen, Chung-Ming Hsieh, Jije Gu, Susan Morgan-Lappe, Yingchun Li
  • Publication number: 20100074900
    Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: July 8, 2009
    Publication date: March 25, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Tariq Ghayur, Jije Gu, Peter C. Isaakson