Patents by Inventor Jill Ann KUBLBECK

Jill Ann KUBLBECK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CONTINUOUSLY INACTIVATING A VIRUS DURING MANUFACTURE OF A PROTEIN
    Publication number: 20220356454
    Abstract: Methods for continuously inactivating a virus during manufacture of a protein are provided. Steps include (1) combining, at a single predetermined volumetric ratio, a composition including the protein, and a composition including a virus-inactivation reagent, to obtain a treatment composition having a predetermined property for inactivation of a virus; (2) transferring the treatment composition to a treatment vessel; (3) incubating the treatment composition in the treatment vessel at predetermined conditions; and (4) subjecting the treatment composition to a post-treatment processing operation. The single predetermined volumetric ratio has been selected to ensure that the predetermined property of the treatment composition is maintained across a range of concentrations predicted for the protein in the composition including the protein.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 10, 2022
    Inventors: Marcus Andre FIADEIRO, Jonathan COFFMAN, Robert Lee FAHRNER, Jill Ann KUBLBECK, Raquel OROZCO, Jeffrey Richard SALM
  • Methods for continuously inactivating a virus during manufacture of a protein
    Patent number: 11407981
    Abstract: Methods for continuously inactivating a virus during manufacture of a protein are provided. Steps include (1) combining, at a single predetermined volumetric ratio, a composition including the protein, and a composition including a virus-inactivation reagent, to obtain a treatment composition having a predetermined property for inactivation of a virus; (2) transferring the treatment composition to a treatment vessel; (3) incubating the treatment composition in the treatment vessel at predetermined conditions; and (4) subjecting the treatment composition to a post-treatment processing operation. The single predetermined volumetric ratio has been selected to ensure that the predetermined property of the treatment composition is maintained across a range of concentrations predicted for the protein in the composition including the protein.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: August 9, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Marcus Andre Fiadeiro, Jonathan Coffman, Robert Lee Fahrner, Jill Ann Kublbeck, Raquel Orozco, Jeffrey Richard Salm
  • METHODS FOR CONTINUOUSLY INACTIVATING A VIRUS DURING MANUFACTURE OF A PROTEIN
    Publication number: 20190071647
    Abstract: Methods for continuously inactivating a virus during manufacture of a protein are provided. Steps include (1) combining, at a single predetermined volumetric ratio, a composition including the protein, and a composition including a virus-inactivation reagent, to obtain a treatment composition having a predetermined property for inactivation of a virus; (2) transferring the treatment composition to a treatment vessel; (3) incubating the treatment composition in the treatment vessel at predetermined conditions; and (4) subjecting the treatment composition to a post-treatment processing operation. The single predetermined volumetric ratio has been selected to ensure that the predetermined property of the treatment composition is maintained across a range of concentrations predicted for the protein in the composition including the protein.
    Type: Application
    Filed: March 10, 2017
    Publication date: March 7, 2019
    Inventors: Marcus Andre FIADEIRO, Jonathan COFFMAN, Robert Lee FAHRNER, Jill Ann KUBLBECK, Raquel OROZCO, Jeffrey Richard SALM