Abstract: Provided herein are compounds which are useful as antagonists of the muscarinic acetylcholine receptor M1 (mAChR M1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.

Abstract: A business reply mail payment system and method is provided. A business reply mail payment system establishes a master account with the postal system for the payment of business reply mail. A plurality of mailers each establish a separate account with the payment system and transfer control of payment for business reply mail accepted under their respective permit imprints to the payment system. When the mailer will be receiving business reply mail, a request for payment of postage is made to the payment system, which processes the information related to the business reply mail. The post office acceptance site communicates with the payment system as the business reply mail is received and compares the received business reply mail with the information processed by the payment system to determine if it should be accepted or rejected. If the business reply mail is accepted, the master account is debited for payment.