Patents by Inventor Jill Coursen

Jill Coursen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identifying inhibitors of GADD45 polypeptide activity, and inhibitors of such activity
    Publication number: 20060280683
    Abstract: The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability of Cdc2/cyclin B1 complexes to cause a pause at the G2/M stage of the cell cycle in response to GADD45, and nucleic acids which encode such polypeptides.
    Type: Application
    Filed: August 17, 2006
    Publication date: December 14, 2006
    Applicant: The Government of the U.S, as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: Xin Wang, Curtis Harris, Albert Fornace, Jill Coursen, Qimin Zhan
  • Methods of identifying inhibitors of GADD45 polypeptide activity, and inhibitors of such activity
    Publication number: 20060088888
    Abstract: The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability of Cdc2/cyclin B1 complexes to cause a pause at the G2/M stage of the cell cycle in response to GADD45, and nucleic acids which encode such polypeptides.
    Type: Application
    Filed: December 7, 2005
    Publication date: April 27, 2006
    Applicants: Health and Human Services
    Inventors: Xin Wang, Curtis Harris, Albert Fornace, Jill Coursen, Qimin Zhan