Patents by Inventor Jill E. Hochlowski

Jill E. Hochlowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antifungal fusacandins
    Patent number: 5773421
    Abstract: Novel antifungal agents having the formula: ##STR1## wherein R is hydrogen or --C(O)--R.sub.1 wherein R.sub.1 is alkenyl, C.sub.2 -C.sub.12 -alkyl, aryl, arylalkenyl, arylalkyl, aryl-aryl-, arylalkoxy-aryl-, aryloxyl-aryl-, aryl-aryl-aryl- or arylalkoxy-aryl-aryl-, or pharmaceutically acceptable salts, esters or prodrugs thereof, as well as (i) pharmaceutical compositions comprising such compounds, (ii) methods of treatment using such compounds, and (iv) methods and fungal cultures useful in making the same.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: June 30, 1998
    Assignee: Abbott Laboratories
    Inventors: Lisa A. Alder, Marianna Jackson, Neal S. Burres, James B. McAlpine, Jill E. Hochlowski, Larry L. Klein, Paul A. Lartey, Clinton Yeung
  • Bromotiacumicin compounds
    Patent number: 5767096
    Abstract: Antimicrobial compounds having the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of hydrogen and C.sub.1 -to-C.sub.4 alkanoyl;R.sup.3 and R.sup.4 are selected from the group consisting of(a) R.sup.3 is hydrogen and R.sup.4 is hydroxy,(b) R.sup.3 is hydroxy and R.sup.4 is hydrogen,(c) R.sup.3 and R.sup.4 taken together are .dbd.O; or selected from the group consisting of hydrogen and hydroxy; andR.sup.5 and R.sup.6 are independently selected from the group consisting of hydrogen, bromine and chlorine, with the proviso that at least one of R.sup.5 and R.sup.6 must be bromine. Also disclosed are pharmaceutical compositions comprising such compounds, methods of treating bacterial infection by the administration thereof and a process for preparing said compounds.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: June 16, 1998
    Assignee: Abbott Laboratories
    Inventors: Jill E. Hochlowski, Marianna Jackson, James B. McAlpine, Ronald R. Rasmussen
  • Dorrigocin antitumor agents
    Patent number: 5589485
    Abstract: Novel antifungal and antitumor agents having the formula ##STR1## as well as pharmaceutically acceptable salts, esters, amides and pro-drugs thereof, wherein R is selected from the group consisting of ##STR2## Also disclosed are pharmaceutical compositions comprising such compounds, and methods of treatment and processes of manufacture relating thereto.
    Type: Grant
    Filed: April 26, 1995
    Date of Patent: December 31, 1996
    Assignee: Abbott Laboratories
    Inventors: Jill E. Hochlowski, Marianna Jackson, Sunil K. Kadam, James P. Karwowski, James B. McAlpine
  • Fungal isolates, fusacandins
    Patent number: 5585251
    Abstract: Novel antifungal agents having the formula: ##STR1## wherein R is hydrogen or a radical of the formula ##STR2## and pharmaceutically acceptable prodrugs thereof, as well as (i) pharmaceutical compositions comprising such compounds, (ii) methods of treatment using such compounds, and (iv) methods and fungal cultures useful in making the same.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: December 17, 1996
    Assignee: Abbott Laboratories
    Inventors: Lisa A. Alder, Neal S. Burres, Jill E. Hochlowski, Marianna Jackson, James B. McAlpine
  • Dialkyltiacumicin compounds
    Patent number: 5583115
    Abstract: Antimicrobial compounds having the formula ##STR1## as well as pharmaceutical compositions comprising such compounds and methods of treating bacterial infection and colitis by the administration thereof.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: December 10, 1996
    Assignee: Abbott Laboratories
    Inventors: James B. McAlpine, Jill E. Hochlowski
  • Antifungal dorrigocin derivatives
    Patent number: 5484799
    Abstract: Novel antifungal and antitumor agents having the formula ##STR1## as well as pharmaceutically acceptable salts, esters, amides and pro-drugs thereof, wherein R is selected from the group consisting of ##STR2## Also disclosed are pharmaceutical compositions comprising such compounds, and methods of treatment and processes of manufacture relating thereto.
    Type: Grant
    Filed: December 9, 1993
    Date of Patent: January 16, 1996
    Assignee: Abbott Laboratories
    Inventors: Jill E. Hochlowski, Marianna Jackson, Sunil K. Kadam, James P. Karwowski, James B. McAlpine
  • Antibiotics unphenelfamycin and phenelfamycins A-D
    Patent number: 5192748
    Abstract: New antibiotics, unphenelfamycin and phenelfamycins A-D, are produced by microorganisms belonging to the genus Streptomyces. The antibiotics have antibacterial activity against gram-positive and gram-negative anaerobic organisms and are effective in improving the feed efficiency and growth rate of livestock, including poultry.
    Type: Grant
    Filed: August 5, 1991
    Date of Patent: March 9, 1993
    Assignee: Abbott Laboratories
    Inventors: Jill E. Hochlowski, Mark H. Buytendorp, Randal H. Chen, James B. McAlpine, Robert J. Theriault, Marianna Jackson, James P. Karwowski