Patents by Inventor Jill F Magnus

Jill F Magnus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using MIR34 as a biomarker for TP53 functional status
    Patent number: 8399248
    Abstract: In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: March 19, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus, Lin He, Xingyue He, Scott W. Lowe, Gregory J. Hannon
  • Compositions comprising MIR34 therapeutic agents for treating cancer
    Patent number: 8378088
    Abstract: In one aspect, the invention generally relates to compositions comprising miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: February 19, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michele A Cleary, Aimee L Jackson, Peter S Linsley, Julja Burchard, Lee P Lim, Jill F Magnus
  • METHODS OF USING MIR34 AS A BIOMARKER FOR TP53 FUNCTIONAL STATUS
    Publication number: 20110105583
    Abstract: In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Application
    Filed: May 5, 2008
    Publication date: May 5, 2011
    Applicants: MERCK & CO., INC., COLD SPRING HARBOR LABORATORY
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus, Lin He, Xingyue He, Scott W. Lowe, Gregory J. Hannon
  • METHODS FOR DETECTING GENETIC VARIATIONS IN DNA SAMPLES
    Publication number: 20110003301
    Abstract: The invention provides methods, compositions and kits for detecting genetic variation in a DNA sample at one or more polymorphic loci of interest. In some embodiments, the invention provides methods, compositions, and kits for determining the nucleotide present at a single nucleotide variant position of interest in a test sample.
    Type: Application
    Filed: May 7, 2010
    Publication date: January 6, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Christopher K. RAYMOND, Jill F. MAGNUS
  • COMPOSITIONS COMPRISING MIR34 THERAPEUTIC AGENTS FOR TREATING CANCER
    Publication number: 20100227909
    Abstract: In one aspect, the invention generally relates to compositions comprising miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Application
    Filed: May 5, 2008
    Publication date: September 9, 2010
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus