Patents by Inventor Jill Giles-Komar

Jill Giles-Komar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating psoriatic arthritis by administering an anti-IL-12 antibody
    Patent number: 8329171
    Abstract: Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as psoriatic arthritis.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: December 11, 2012
    Assignee: Janssen Biotech, Inc.
    Inventors: Jill Giles-Komar, David M. Knight, David Peritt, Bernard Scallon, David Shealy
  • Method for treating psoriasis by administering an anti-IL-12 antibody
    Patent number: 8329170
    Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in treating IL-12-related disorders, such as psoriasis.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: December 11, 2012
    Assignee: Janssen Biotech, Inc.
    Inventors: Jill Giles-Komar, George Heavner, David Knight, Jinquan Luo, David Peritt, Bernard Scallon, David Shealy
  • Engineered anti-IL-13 antibodies, compositions, methods and uses
    Patent number: 8323646
    Abstract: The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: December 4, 2012
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov, Yiging Feng
  • ANTI- TNF ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20120282170
    Abstract: The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 8, 2012
    Inventors: George Heavner, David M. Knight, Jill Giles-Komar, Bernard Scallon, David Shealy
  • Method for Treating Psoriasis by Administering An Anti-IL-12 Antibody
    Publication number: 20120207670
    Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in treating IL-12-related disorders, such as psoriasis.
    Type: Application
    Filed: November 18, 2011
    Publication date: August 16, 2012
    Inventors: Jill Giles-Komar, George Heavner, David Knight, Jinquan Luo, David Peritt, Bernard Scallon, David Shealy
  • Anti-TNF antibodies, compositions, methods and uses
    Patent number: 8241899
    Abstract: The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: August 14, 2012
    Assignee: Centocor, Inc.
    Inventors: George Heavner, David M. Knight, Jill Giles-Komar, Bernard Scallon, David Shealy
  • Enhancement of hybridoma fusion efficiencies through cell synchronization
    Patent number: 8216842
    Abstract: The present invention provides methods of enhancing hybridoma fusion efficiencies through cell synchronization of the fusion partners, in order to aid in production of antibodies.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: July 10, 2012
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Jill Giles-Komar, Michael Rycyzyn, Gregory Bannish
  • ANTI-IL-6 ANTIBODIES,COMPOSITIONS, METHODS AND USES
    Publication number: 20120096569
    Abstract: The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: December 21, 2011
    Publication date: April 19, 2012
    Inventors: Jill Giles-Komar, David Knight, David Peritt, Mohit Trikha
  • Method for Treating Psoriatic Arthritis by Administering an Anti-IL-12 Antibody
    Publication number: 20120063998
    Abstract: Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as psoriatic arthritis.
    Type: Application
    Filed: November 18, 2011
    Publication date: March 15, 2012
    Inventors: Jill Giles-Komar, David M. Knight, David Peritt, Bemard Scallon, David Shealy
  • ANTI- INTEGRIN ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20120058128
    Abstract: The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Inventors: Jill Giles-Komar, Linda Snyder, Mohit Trikha, Marian T. Nakada
  • ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20120045438
    Abstract: The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 23, 2012
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov, Yiqing Feng
  • Nucleic acids encoding anti-IL-12 antibody
    Patent number: 8084233
    Abstract: Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: December 27, 2011
    Assignee: Janssen Biotech, Inc.
    Inventors: Jill Giles-Komar, David M. Knight, David Peritt, Bernard Scallon, David Shealy
  • Anti-IL-12 antibodies
    Patent number: 8080247
    Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: December 20, 2011
    Assignee: Janssen Biotech, Inc.
    Inventors: Jill Giles-Komar, George Heavner, David Knight, Jinquan Luo, David Peritt, Bernard Scallon, David Shealy
  • Anti-integrin antibodies, compositions, methods and uses
    Patent number: 8071333
    Abstract: The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: December 6, 2011
    Assignee: Centocor, Inc.
    Inventors: Jill Giles-Komar, Linda Snyder, Mohit Trikha, Marian T. Nakada
  • Anti-integrin antibodies, compositions, methods and uses
    Patent number: 8071729
    Abstract: The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 6, 2011
    Assignee: Centocor, Inc.
    Inventors: Jill Giles-Komar, Linda Snyder, Mohit Trikha, Marian T. Nakada
  • ANTI-IL-6 ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20110218329
    Abstract: The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: May 11, 2011
    Publication date: September 8, 2011
    Inventors: Jill Giles-Komar, David Knight, David Peritt, Mohit Trikha
  • Anti-IL-6 antibodies, compositions, methods and uses
    Patent number: 7955597
    Abstract: The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: June 7, 2011
    Assignee: Centocor, Inc.
    Inventors: Jill Giles-Komar, David Knight, David Peritt, Mohit Trikha
  • Nucleic Acids Encoding Anti-IL-12 Antibody
    Publication number: 20110082190
    Abstract: Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 7, 2011
    Inventors: Jill Giles-Komar, David M. Knight, David Peritt, Bernard Scallon, David Shealy
  • Anti-IL-12 antibodies and compositions
    Patent number: 7887807
    Abstract: Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: February 15, 2011
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Jill Giles-Komar, David M. Knight, David Peritt, Bernard Scallon, David Shealy
  • Anti-IL-6 antibodies, compositions, methods and uses
    Patent number: 7833786
    Abstract: The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: November 16, 2010
    Assignee: Centocor, Inc.
    Inventors: Jill Giles-Komar, David Knight, David Peritt, Mohit Trikha