Patents by Inventor Jill HERSCHLEB

Jill HERSCHLEB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spatial analysis utilizing degradable hydrogels
    Patent number: 11981960
    Abstract: Provided are methods of capturing an analyte from a biological sample using a hydrogel that includes capture probes to capture the analyte, identifying a region of interest of the biological sample, and isolating the region of interest from the biological sample by removing a portion of the hydrogel that corresponds to the region of interest. Compositions and kits for performing the methods are also provided.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: May 14, 2024
    Assignee: 10x Genomics, Inc.
    Inventors: Bill Kengli Lin, Jill Herschleb, Cedric Uytingco
  • COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS
    Publication number: 20240125772
    Abstract: The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cleaving crosslinks in fixed biological samples, particularly crosslinked nucleic acids, such as RNA.
    Type: Application
    Filed: November 7, 2023
    Publication date: April 18, 2024
    Inventors: Joshua Delaney, Shalini Gohil, Jill Herschleb, Adam Lowe, Albert Kim, Meiliana Tjandra
  • COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS
    Publication number: 20210190770
    Abstract: The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cleaving crosslinks in fixed biological samples, particularly crosslinked nucleic acids, such as RNA.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 24, 2021
    Applicant: 10X Genomics, Inc.
    Inventors: Joshua DELANEY, Shalini GOHIL, Jill HERSCHLEB, Adam LOWE, Albert KIM, Meiliana TJANDRA