Abstract: Systems and methods are disclosed for the utilization of personally identifiable information (PII) to identify an individual while de-identifying the associated data through tokenization. A method includes receiving, at a main tokenizer and from a first trading partner, a first data set comprising a first subset of a plurality of PII fields corresponding to an individual, receiving, at the main tokenizer and from a second trading partner, a second data set comprising a second subset of the plurality of PII fields corresponding to the individual, resolving, a the main tokenizer, the individual, linking a unique patient-centric token (PCT) to the individual based on the resolving, and outputting the PCT for generating a non-PII token linked to the individual.