Patents by Inventor Jill P. Mesirov

Jill P. Mesirov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signatures and determinants associated with cancer and methods of use thereof
    Patent number: 9593377
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: March 14, 2017
    Assignees: Dana-Farber Cancer Institute, Inc., The Broad Institute, Inc.
    Inventors: William C. Hahn, Pablo Tamayo, Jesse S. Boehm, Jill P. Mesirov
  • Signatures and Determinants Associated with Cancer and Methods of Use Thereof
    Publication number: 20130323744
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Application
    Filed: November 30, 2011
    Publication date: December 5, 2013
    Applicants: The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: William C. Hahn, Pablo Tamayo, Jesse S. Boehm, Jill P. Mesirov
  • Methods for predicting chemosensitivity or chemoresistance
    Patent number: 7324926
    Abstract: Methods and apparatus for classifying or predicting the classes for samples based on gene expression are described. Also described are methods and apparatus for ascertaining or discovering new, previously unknown classes based on gene expression. Methods, computer systems and apparatus for classifying or predicting whether a sample is treatment sensitive (e.g., chemosensitive) or treatment resistant (e.g., chemoresistant) are also provided. Classification occurs based on analysis of gene expression data from samples that have been subjected to one or more compounds.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: January 29, 2008
    Assignees: Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Inc.
    Inventors: Pablo Tamayo, Jane E. Staunton, Donna K. Slonim, Hilary A. Coller, Todd R. Golub, Eric S. Lander, Jill P. Mesirov
  • Across platform and multiple dataset molecular classification
    Publication number: 20040098367
    Abstract: Systems and methods for across platform and multiple dataset classification. In one embodiment the systems combine a Large Bayes classification framework, constructed from discovered itemsets or common patterns of data, with a definition of combined relative features to represent the original values. One realization of this method is that different datasets representing the same biological system display some amount of invariant biological characteristics independent of the idiosyncrasies of sample sources, preparation and the technological platform used to obtain the measurements.
    Type: Application
    Filed: August 6, 2003
    Publication date: May 20, 2004
    Applicants: Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute
    Inventors: Pablo Tamayo, Jill P. Mesirov, Todd Golub
  • Methods for predicting chemosensitivity or chemoresistance
    Publication number: 20030073083
    Abstract: Methods and apparatus for classifying or predicting the classes for samples based on gene expression are described. Also described are methods and apparatus for ascertaining or discovering new, previously unknown classes based on gene expression. Methods, computer systems and apparatus for classifying or predicting whether a sample is treatment sensitive (e.g., chemosensitive) or treatment resistant (e.g., chemoresistant) are also provided. Classification occurs based on analysis of gene expression data from samples that have been subjected to one or more compounds.
    Type: Application
    Filed: October 1, 2001
    Publication date: April 17, 2003
    Inventors: Pablo Tamayo, Jane E. Staunton, Donna K. Slonim, Hilary A. Coller, Todd R. Golub, Eric S. Lander, Jill P. Mesirov
  • Methods and apparatus for analyzing gene expression data
    Publication number: 20020115070
    Abstract: The present invention relates to methods and apparatus for grouping or clustering gene expression patterns from a plurality of genes. The invention utilizes a Self Organizing Map to cluster the gene expression patterns into groups that exhibit similar patterns. The clustering enables one to easily analyze gene expression data from potentially thousands of genes.
    Type: Application
    Filed: March 14, 2000
    Publication date: August 22, 2002
    Inventors: Pablo Tamayo, Jill P. Mesirov, Eric S. Lander, Todd R. Golub
  • Methods for assembly of genetic information
    Publication number: 20020049547
    Abstract: Disclosed herein are methods and articles of manufacture for assembly of a plurality of reads from a genomic region that include the steps of indexing a plurality of read subsequences for each of a plurality of reads, extracting from the indexed subsequences a plurality of read pairs that have a predetermined number of subsequences in common, and merging the read pairs along a continuum. Also disclosed are methods and articles of manufacture for assembly of merged reads from a genomic region that include the steps of using linking information to identify one or more ambiguities in the merged reads, identifying a repeat region and a set of unique regions, and linking pairs of unique regions using the linking information associated with the reads in the unique regions.
    Type: Application
    Filed: June 13, 2001
    Publication date: April 25, 2002
    Inventors: Serafim Batzoglou, Bonnie Berger, Jill P. Mesirov, Eric Lander