Patents by Inventor Jillian F. Evans
Jillian F. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8710081Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: GrantFiled: July 16, 2013Date of Patent: April 29, 2014Assignee: Panmira Pharmaceuticals, LLCInventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Jasmine Eleanor Zunic, Nicholas Simon Stock
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Publication number: 20140018394Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: July 16, 2013Publication date: January 16, 2014Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Jasmine Eleanor Zunic, Nicholas Simon Stock
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Patent number: 8546431Abstract: A method for treating a human comprises administering a therapeutically effective amount of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid or a pharmaceutically acceptable salt or a pharmaceutically acceptable N-oxide thereof, to the human in need.Type: GrantFiled: October 30, 2012Date of Patent: October 1, 2013Assignee: Panmira Pharmaceuticals, LLCInventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Yiwei Li, Jeannie M. Arruda
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Patent number: 8399666Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: GrantFiled: October 30, 2006Date of Patent: March 19, 2013Assignee: Panmira Pharmaceuticals, LLCInventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Brian Andrew Stearns, Jeffrey Roger Roppe, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Mustapha Haddach
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Publication number: 20120027842Abstract: Described herein are topical formulations for administration to an eye, wherein the formulation is administered to treat ophthalmic diseases, disorders, or conditions. A topical formulation for administration to an eye disclosed herein comprises a therapeutically-effective amount of a FLAP inhibitor compound formulated for topical administration to the eye.Type: ApplicationFiled: December 21, 2009Publication date: February 2, 2012Applicant: Amira Pharmaceuticals, Inc.Inventors: John Howard Hutchinson, Jillian F. Evans, Nicholas Simon Stock
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Publication number: 20110311613Abstract: Described herein, are topical formulations for treating a dermatological disease, disorder, or condition.Type: ApplicationFiled: December 21, 2009Publication date: December 22, 2011Applicant: AMIRA PHARMACEUTICAL, INC.Inventors: John Howard Hutchinson, Jillian F. Evans, Kevin Murray Schaab
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Patent number: 7977359Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: GrantFiled: October 27, 2006Date of Patent: July 12, 2011Assignee: Amira Pharmaceuticals, Inc.Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Brian Andrew Stearns, Jeffrey Roger Roppe, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Mustapha Haddach
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Publication number: 20110118315Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: January 24, 2011Publication date: May 19, 2011Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Brian Andrew Stearns, Mustapha Haddach, Jeffrey Roger Roppe
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Publication number: 20100173313Abstract: Methods for the detection of DP2 receptors in biological samples is disclosed. The induction and detection of DP2 receptors expressed on activated human neutrophils is presented. Also presented are diagnostic kits for the detection of DP2 receptors in biological samples.Type: ApplicationFiled: January 8, 2010Publication date: July 8, 2010Applicant: AMIRA PHARMACEUTICALS, INC.Inventors: Gretchen BAIN, John Howard HUTCHINSON, Brian Andrew STEARNS, Kevin Murray SCHAAB, Jillian F. EVANS
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Publication number: 20100075934Abstract: Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates thereof. Also described are pharmaceutical compositions suitable for oral administration to a mammal that include, as well as methods of using such oral pharmaceutical compositions for treating respiratory conditions or diseases, as well as other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: October 24, 2008Publication date: March 25, 2010Applicant: Amira Pharmaceuticals, Inc.Inventors: Melissa Virginia REWOLINSKI, Kevin Murray SCHAAB, Christopher David KING, Jillian F. EVANS, Petpiboon Peppi PRASIT, John Howard HUTCHINSON, Nicholas Simon STOCK
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Publication number: 20090221574Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: November 3, 2006Publication date: September 3, 2009Applicant: AMIRA PHARMACEUTICALS, INC.Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Yiwei Li, Jasmine Eleanor Zunic, Mustapha Haddach, Nicholas Simon Stock
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Publication number: 20090192171Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: October 30, 2006Publication date: July 30, 2009Applicant: AMIRA PHARMACEUTICALS, INC.Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Brian Andrew Stearns, Jeffrey Roger Roppe, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Mustapha Haddach
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Publication number: 20080227807Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: ApplicationFiled: June 2, 2008Publication date: September 18, 2008Applicant: AMIRA PHARMACEUTICALS, INC.Inventors: John H. HUTCHINSON, Petpiboon Peppi PRASIT, Mark MORAN, Jillian F. EVANS, Jasmine Eleanor ZUNIC, Nicholas Simon STOCK
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Patent number: 7405302Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Type: GrantFiled: October 4, 2006Date of Patent: July 29, 2008Assignee: Amira Pharmaceuticals, Inc.Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Jasmine Eleanor Zunic, Nicholas Simon Stock
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Patent number: 5459239Abstract: This invention discloses novel immunogenic peptide sequences, derived from the human cyclooxygenase-1 and cyclooxygenase-2 cDNAs which elicit specific non cross-reactive antibody responses. Assays are also disclosed for selectively and independently detecting cyclooxygenase-1 or cyclooxygenase-2 proteins present in a given biological sample.Type: GrantFiled: January 24, 1994Date of Patent: October 17, 1995Assignee: Merck Frosst Canada Inc.Inventors: Gary O'Neill, Philip J. Vickers, Stacia Kargman, Jillian F. Evans
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Patent number: 5182367Abstract: An 18kD protein (FLAP) has been isolated from rat and human cells which is necessary for production of leukotrienes from arachidonic acid in mammalian cells containing 5-lipoxygenase. The gene (cDNA) encoding for FLAP has also been produced.Type: GrantFiled: November 30, 1990Date of Patent: January 26, 1993Assignees: Merck & Co., Inc., Merck Frosst Canada, Inc.Inventors: John W. Gillard, Jacques-Yves Gauthier, Jillian F. Evans, Rejean Fortin, Yvan Guinon, Richard A. F. Dixon, Douglas K. Miller