Patents by Inventor Jillian GENTILE

Jillian GENTILE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH CONCENTRATION ANTI-C5 ANTIBODY FORMULATIONS
    Publication number: 20230257456
    Abstract: The present disclosure relates to stable aqueous solutions comprising a high concentration of an anti-05 antibody (e.g., ravulizumab) and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), using the solutions. Also featured were therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
    Type: Application
    Filed: December 21, 2022
    Publication date: August 17, 2023
    Inventors: Stephan ORTIZ, Jillian GENTILE, Leena PHILOMINATHAN, Eric ROUTHIER, Bruce MASON
  • HIGH CONCENTRATION ANTI-C5 ANTIBODY FORMULATIONS
    Publication number: 20230106734
    Abstract: The present disclosure relates to stable aqueous solutions comprising a high concentration of an anti-C5 antibody (e.g., ravulizumab) and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), using the solutions. Also featured were therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
    Type: Application
    Filed: May 6, 2022
    Publication date: April 6, 2023
    Inventors: Stephan ORTIZ, Jillian GENTILE, Leena PHILOMINATHAN, Eric ROUTHIER, Bruce MASON
  • High concentration anti-C5 antibody formulations
    Patent number: 11365241
    Abstract: The present disclosure relates to stable aqueous solutions comprising a high concentration of an anti-C5 antibody (e.g., ravulizumab) and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), using the solutions. Also featured were therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 21, 2022
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Stephan Ortiz, Jillian Gentile, Leena Philominathan, Eric Routhier, Bruce Mason
  • HIGH CONCENTRATION ANTI-C5 ANTIBODY FORMULATIONS
    Publication number: 20200369751
    Abstract: The present disclosure relates to stable aqueous solutions comprising a high concentration of an anti-C5 antibody (e.g., ravulizumab) and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), using the solutions. Also featured were therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 26, 2020
    Inventors: Stephan ORTIZ, Jillian GENTILE, Leena PHILOMINATHAN, Eric ROUTHIER, Bruce MASON