Patents by Inventor Jim Broach

Jim Broach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Patent number: 7611854
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of ?-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: November 3, 2009
    Assignee: Cadus Technologies, Inc.
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Patent number: 7416881
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of ?-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: August 26, 2008
    Assignee: Cadus Technologies, Inc.
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Patent number: 7235648
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of ?-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: June 26, 2007
    Assignee: Cadus Technologies, Inc.
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Publication number: 20040197840
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of &agr;-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Application
    Filed: June 18, 2003
    Publication date: October 7, 2004
    Applicant: Cadus Technologies, Inc.
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Publication number: 20030008380
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of &agr;-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Application
    Filed: May 10, 1999
    Publication date: January 9, 2003
    Inventors: DANA MERRIMAN FOWLKES, JIM BROACH, JOHN MANFREDI, CHRISTINE KLEIN, ANDREW J. MURPHY, DR. JEREMY PAUL, JOSHUA TRUEHEART
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Patent number: 6100042
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of .alpha.-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: August 8, 2000
    Assignee: Cadus Pharmaceutical Corporation
    Inventors: Dana Merriman Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates and uses therefor
    Patent number: 5876951
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of .alpha.-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 2, 1999
    Assignee: Cadus Pharmaceutical Corporation
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart
  • Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
    Patent number: 5789184
    Abstract: Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of .alpha.-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 4, 1998
    Assignee: Cadus Pharmaceutical Corporation
    Inventors: Dana M. Fowlkes, Jim Broach, John Manfredi, Christine Klein, Andrew J. Murphy, Jeremy Paul, Joshua Trueheart