Abstract: Compounds for the treatment of estrogen-receptor related maladies are provided. Compounds with anti-androgenic properties also are provided. In particular, the invention provides compounds that are tetrahydroquinoline phenylamide derivatives and are useful for the treatment of breast and prostate cancer, and osteoporosis.

Abstract: This infrastructure computer and program uses information supplied by sensors to calculate the operational characteristics of back up systems located at central offices during times of crisis such as the loss of commercial power, or some other natural or man-made disaster. The sensors transmit the battery float voltage, power requirements, temperature of critical telecommunication equipment components, average telecommunication equipment temperature, and the amount of fuel available for backup generators provides data to an infrastructure management computer program. The computer program accesses databases containing known information such as the power curves for the backup generators, and battery discharge curves for the battery string. The infrastructure management computer program calculates the battery hour reserve, the fuel hour reserve, and thermal reserves to more accurately predict the operational status of the central office for improved disaster planning.