Abstract: Systems and methods for improving perceived image quality of an electronic display, which includes a display region with a rounded border and a display pixel at a pixel position adjacent the rounded border. A display pipeline communicatively coupled to the electronic display receives first image data that indicates target luminance at the pixel position in a rectangular image frame; determines a gain value associated with the pixel position from a gain map, in which the gain value is inversely proportional to distance between the display pixel and the rounded border; determines second image data that indicates target luminance of the display pixel by processing the first image data based at least in part on the gain value; and outputs the second image data to the electronic display to facilitate displaying a non-rectangular portion of the image frame on the display region.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants in response to the query.

Abstract: Systems, platforms, methods and media for providing genomic services axe disclosed. In one example, a system for providing genomic services comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, store the sequence reads in a FASTQ storage file, and communicate the FASTQ file electronically to a recipient. The system also includes a genomic services platform which includes a network interface through which the sequence reads are received, and a bioinformatics processing pipeline. The bioinformatics processing pipeline includes a read alignment module configured to generate observed sequence data, and a variant calling module is operative to identify observed variants in the observed sequence data. A variant storage module is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of refined variants in response to a query.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user. The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing genotype data including a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and is configured to receive, as input, at least some of the genotype data and separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

Abstract: Methods, systems and media for providing genomic services are disclosed. In one example, a system comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, and a genomic services platform. The platform includes a network interface through which the sequence reads are received. A bioinformatics processing pipeline includes a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, and a variant calling module is operative to identify observed variants in the observed sequence data. Genomic data storage contains the observed variants in the observed sequence data. A variant storage module is disposed to receive a query from network infrastructure of a partner application provider and to provide genomic information based on or derived from the observed variants in response to the query.

Abstract: Methods, systems and media for providing genomic services are disclosed. In one example, a system for providing genomic services comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, and a genomic services platform. The platform includes genomic data storage containing observed sequence data generated by aligning the sequence reads relative to a reference sequence and variants in the observed sequence data derived from the observed sequence data. File storage includes one or more files defining one or more genomic windows respectively associated with each of a plurality of partner application providers or partner applications.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a platform comprises a network interface, in communication with a sequencing laboratory, through which are received genomic sequence reads derived from a biological sample obtained from a user, and a bioinformatics processing pipeline. The pipeline includes a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, a genomic data storage containing at least the observed variants in the observed sequence data, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide genomic information based on or derived from the observed variants in response to the query.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants in response to the query.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample obtained from a user are received. The platform also includes a bioinformatics processing pipeline that includes a read alignment module configured to receive a genomics file from genomic sequencing equipment and use data contained therein to generate observed sequence data by aligning the sequence reads relative to a reference sequence. A variant calling module identifies observed variants in the observed sequence data and stores the observed variants in a variant calling file. A variant refinement module produces genotype data including a set of refined variants associated with the user, and a variant imputation module produces a set of imputed variants associated with the user.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user. The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing genotype data including a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and is configured to receive, as input, at least some of the genotype data and separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample are received. The platform also includes a bioinformatics processing pipeline that comprises a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the biological sample. A variant imputation module produces a set of imputed variants associated with the user and a variant storage module, operating on a server-less framework, is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants m response to the query.

Abstract: Systems and methods for improving perceived image quality of an electronic display, which includes a co-located sub-pixel that controls luminance of a first color component and an offset sub-pixel that controls luminance of a second color component. A display pipeline communicatively coupled to the electronic display determines image data, which indicates target luminance of the first, the second, and a third color component at an image pixel; determines edge parameters, which indicate whether an edge is expected to be present at the offset sub-pixel, based on a difference metric between a first image pixel block around the offset sub-pixel and a second image pixel block offset from the first image pixel block; and determines offset sub-pixel image data by filtering an image pixel group around the offset sub-pixel based at least in part on the edge parameters, wherein the offset sub-pixel image data indicates target luminance of the offset sub-pixel.

Abstract: Systems and methods for improving perceived image quality of an electronic display, which includes a display region with a rounded border and a display pixel at a pixel position adjacent the rounded border. A display pipeline communicatively coupled to the electronic display receives first image data that indicates target luminance at the pixel position in a rectangular image frame; determines a gain value associated with the pixel position from a gain map, in which the gain value is inversely proportional to distance between the display pixel and the rounded border; determines second image data that indicates target luminance of the display pixel by processing the first image data based at least in part on the gain value; and outputs the second image data to the electronic display to facilitate displaying a non-rectangular portion of the image frame on the display region.

Abstract: In one embodiment, a method includes receiving at a multimedia transformation unit, media streams from a plurality of endpoints, transmitting audio components of the media streams to a multipoint conferencing unit, receiving an identifier from the multipoint conferencing unit identifying one of the media streams as an active speaker stream, processing at the multimedia transformation unit, a video component of the active speaker stream, and transmitting the active speaker stream to one or more of the endpoints without transmitting the video component to the multipoint conferencing unit. An apparatus is also disclosed herein.

Abstract: In one embodiment, a method includes receiving at a network device, video from a first endpoint, analyzing the video received from the first endpoint, processing video received from a second endpoint based on the analyzed video to optimize bandwidth between the network device and the first endpoint, and transmitting the processed video to the first endpoint. An apparatus is also disclosed.

Abstract: In one embodiment, a method includes receiving at a multimedia transformation unit, media streams from a plurality of endpoints, transmitting audio components of the media streams to a multipoint conferencing unit, receiving an identifier from the multipoint conferencing unit identifying one of the media streams as an active speaker stream, processing at the multimedia transformation unit, a video component of the active speaker stream, and transmitting the active speaker stream to one or more of the endpoints without transmitting the video component to the multipoint conferencing unit. An apparatus is also disclosed herein.

Abstract: In one embodiment, a method includes receiving at a multimedia transformation unit, media streams from a plurality of endpoints, transmitting audio components of the media streams to a multipoint conferencing unit, receiving an identifier from the multipoint conferencing unit identifying one of the media streams as an active speaker stream, processing at the multimedia transformation unit, a video component of the active speaker stream, and transmitting the active speaker stream to one or more of the endpoints without transmitting the video component to the multipoint conferencing unit. An apparatus is also disclosed.

Abstract: In one embodiment, a method includes identifying priority objects in a composite image created from one or more input video streams, processing the composite image, and generating a plurality of output video streams. The output video streams correspond to display screens available for viewing the output video streams and the number of output video streams is different than the number of input video streams. Processing the composite image includes positioning the priority objects to prevent placement of the priority objects at a location extending over two of the display screens. An apparatus is also disclosed.

Abstract: In one embodiment, a method includes receiving at a network device, video from a first endpoint, analyzing the video received from the first endpoint, processing video received from a second endpoint based on the analyzed video to optimize bandwidth between the network device and the first endpoint, and transmitting the processed video to the first endpoint. An apparatus is also disclosed.

Abstract: In one embodiment, a method includes identifying priority objects in a composite image created from one or more input video streams, processing the composite image, and generating a plurality of output video streams. The output video streams correspond to display screens available for viewing the output video streams and the number of output video streams is different than the number of input video streams. Processing the composite image includes positioning the priority objects to prevent placement of the priority objects at a location extending over two of the display screens. An apparatus is also disclosed.