Abstract: Downhole Electric Submersible Pumps (ESP) in a production string often experience gas lock caused by free gas present in the production liquids which reduces intake pressure below the operating parameters of the ESP. A gas compression separator assembly, having a series of compressors and separation chambers, entrains or dissolves the free gas component of the production fluid and separates free gas for downhole disposal. The production fluid fed to the ESP intake has an increased fluid pressure, a reduced volumetric fluid flow, and a lower free gas content, and is less likely to induce gas lock of the ESP.