Patents by Inventor Jim Flatt

Jim Flatt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation and characterization of cellobiohydrolase I (Cbh 1)
    Patent number: 8470592
    Abstract: The present invention provides for the isolation and characterization of the cbh1 gene from Schizochytrium aggregatum. In particular, the present invention provides for the nucleic acid and amino acid sequences of Schizochytrium aggregatum cbh1, and domains, variants and derivatives thereof. The present invention further provides for the heterologous expression of Schizochytrium aggregatum Cbh1 in host cells, including yeast, e.g., Saccharomyces cerevisiae. Expression of Schizochytrium aggregatum Cbh1 in host cells will augment cellulose digestion and facilitate ethanol production by those host cells on cellulosic substrates. In certain embodiments, heterologous expression in Saccharomyces cerevisiae is in coordination with heterologous expression of other known, or newly identified saccharolytic enzymes. Therefore, the present invention also provides that the novel Schizochytrium aggregatum Cbh1 gene can utilized in a consolidated bioprocessing system.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: June 25, 2013
    Assignee: Mascoma Corporation
    Inventors: Elena E. Brevnova, Jim Flatt, Chhayal Gandhi, Vineet Rajgarhia, John McBride, Anne Warner
  • Isolation and Characterization of Schizochytrium Aggregatum Cellobiohydrolase I (CBH I)
    Publication number: 20110312054
    Abstract: The present invention provides for the isolation and characterization of the cbh1 gene from Schizochytrium aggregatum. In particular, the present invention provides for the nucleic acid and amino acid sequences of Schizochytrium aggregatum cbh1, and domains, variants and derivatives thereof. The present invention further provides for the heterologous expression of Schizochytrium aggregatum Cbh1 in host cells, including yeast, e.g., Saccharomyces cerevisiae. Expression of Schizochytrium aggregatum Cbh1 in host cells will augment cellulose digestion and facilitate ethanol production by those host cells on cellulosic substrates. In certain embodiments, heterologous expression in Saccharomyces cerevisiae is in coordination with heterologous expression of other known, or newly identified saccharolytic enzymes. Therefore, the present invention also provides that the novel Schizochytrium aggregatum Cbh1 gene can utilized in a consolidated bioprocessing system.
    Type: Application
    Filed: July 7, 2009
    Publication date: December 22, 2011
    Applicant: Mascoma Corporation
    Inventors: Elena E. Brevnova, Jim Flatt, Chhayal Gandhi, Vineet Rajgarhia, John McBride, Anne Warner