Patents by Inventor Jim Z. Lu

Jim Z. Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSAYS, METHODS AND COMPOSITIONS FOR DIAGNOSING CANCER
    Publication number: 20180223367
    Abstract: The present invention provides a method and single-tube assay for identification and quantitative analysis of differentially methylated MLH1 promoter sequences that are associated with certain types of cancer in an individual by obtaining a biological sample comprising DNA from the individual, detecting the presence of and measuring the level of methylated MLH1 promoter sequences, and comparing the presence of and level of methylation in the sample to a normalization reference of “normal” beta-actin gene promoters, wherein a difference in the level or pattern of MLH1 methylation of the sample compared to the Actin gene reference level identifies abnormally methylated MLH1 promoter sequences associated with cancer.
    Type: Application
    Filed: November 30, 2016
    Publication date: August 9, 2018
    Applicant: GoPath Global, LLC
    Inventors: Jim Z. Lu, Zhongmin Guo
  • ASSAYS, METHODS AND COMPOSITIONS FOR DIAGNOSING CANCER
    Publication number: 20140242583
    Abstract: The present invention provides a method and single-tube assay for identification and quantitative analysis of differentially methylated MLH1 promoter sequences that are associated with certain types of cancer in an individual by obtaining a biological sample comprising DNA from the individual, detecting the presence of and measuring the level of methylated MLH1 promoter sequences, and comparing the presence of and level of methylation in the sample to a normalization reference of “normal” beta-actin gene promoters, wherein a difference in the level or pattern of MLH1 methylation of the sample compared to the Actin gene reference level identifies abnormally methylated MLH1 promoter sequences associated with cancer.
    Type: Application
    Filed: February 28, 2014
    Publication date: August 28, 2014
    Inventors: Jim Z. Lu, Zhongmin Guo