Abstract: The inventive concept provides a substrate treating method. The substrate treating method includes taking in a substrate to a treating space to mount on a support unit; upwardly moving the support unit after mounting the substrate on the support unit; determining whether the support unit moves normally after the upwardly moving the support unit; and treating the substrate by generating a plasma in the treating space, and wherein at the determining whether the support unit moves normally, before the plasma is generated at the treating space at the treating the substrate, whether a pulse distance matching a predetermined distance data according to a pulse value of a driving unit which pulse-moves a moving body which moves the support unit in a top/down direction, matches a movement distance of the moving body is determined, and an interlock is generated if the pulse distance and the movement distance is different.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: Disclosed are a dental wire supporter, which supports an orthodontic wire and limits the movement of the orthodontic wire in a predetermined direction, and an orthodontic device (orthodontic system) having the same. The dental wire supporter includes a limiter having a wire hole into which an orthodontic wire is inserted, and a support base provided at the limiter in order to fix the limiter to a tooth. One side of the wire hole is blocked and an opposite side of the wire hole is open so that the limiter supports the end of the orthodontic wire in a longitudinal direction of the orthodontic wire.

Abstract: Disclosed are a dental wire supporter, which supports an orthodontic wire and limits the movement of the orthodontic wire in a predetermined direction, and an orthodontic device (orthodontic system) having the same. The dental wire supporter includes a limiter having a wire hole into which an orthodontic wire is inserted, and a support base provided at the limiter in order to fix the limiter to a tooth. One side of the wire hole is blocked and an opposite side of the wire hole is open so that the limiter supports the end of the orthodontic wire in a longitudinal direction of the orthodontic wire.