Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

Abstract: The present invention is directed to various embodiments of a subsea production system. In one illustrative embodiment, a subsea completion system includes a tubing string, a Christmas tree defining a bottom opening adapted to have the tubing string inserted therein, and means for latching the tubing string to prevent movement relative to the Christmas tree. A method includes coupling a tubing string with a Christmas tree above water and landing the Christmas tree on a subsea wellhead.

Abstract: A subsea system comprises a central template that is piled into the seabed and carried wing modules that are connected to the template by hinges. This allows the template to be deployed and the wing modules attached subsequently or for the wing modules to be folded upwardly into a collapsed disposition as the template is deployed. In either case, the template can be deployed through the moonpool of a vessel and does not require a heavy lifting barge. An example of a module usable with the template is a hinge-over guidebase which can allow the commencement of drilling of a well while a manifold and christmas tree are being constructed for subsequent attachment. Thus, installation of the system is easy and drilling of the well can commence quickly.