Abstract: A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. In some embodiments, the second diameter is less than the first diameter, the second material is softer than the first material, and the second pitch is more open than the first pitch. In some embodiments, the inner coil extends proximally beyond the outer coil.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.

Abstract: A vaso-occlusive delivery system includes a vaso-occlusive coil, delivery wire assembly, and a link. The vaso-occlusive coil defines a coil lumen and has first and second coil windings defining a coil opening therebetween. The delivery wire assembly defines a delivery wire lumen, and includes an electrolytic detachment zone, a delivery wire conduit, and a delivery wire attached to the delivery wire conduit and extending through the delivery wire lumen distal of the delivery wire conduit. The link defines a link lumen and has link body including a proximal end of the link body defines an link opening in communication with the link lumen and a distal end of the link body includes a link detent extending radially from the link body, through the coil opening, securing the link body and the delivery wire assembly to the vaso-occlusive coil.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.

Abstract: A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. In some embodiments, the second diameter is less than the first diameter, the second material is softer than the first material, and the second pitch is more open than the first pitch. In some embodiments, the inner coil extends proximally beyond the outer coil.

Abstract: A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. The outer coil defines a lumen and the inner coil is disposed at least partially in the lumen. The vaso-occlusive device also includes an intermediate layer disposed between the inner coil and the outer coil, where the intermediate layer includes a biocompatible metal or a biocompatible, swellable polymer.

Abstract: A vaso-occlusive delivery system includes a vaso-occlusive coil, delivery wire assembly, and a link. The vaso-occlusive coil defines a coil lumen and has first and second coil windings defining a coil opening therebetween. The delivery wire assembly defines a delivery wire lumen, and includes an electrolytic detachment zone, a delivery wire conduit, and a delivery wire attached to the delivery wire conduit and extending through the delivery wire lumen distal of the delivery wire conduit. The link defines a link lumen and has link body including a proximal end of the link body defines an link opening in communication with the link lumen and a distal end of the link body includes a link detent extending radially from the link body, through the coil opening, securing the link body and the delivery wire assembly to the vaso-occlusive coil.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.

Abstract: A vaso-occlusive device includes a first wire having a first cross-sectional geometry and a second wire having a second cross-sectional geometry, where the first cross-sectional geometry is different from the second cross-sectional geometry. The first wire may be wound to form a first coil, where the second wire is wound to form a second coil defining a lumen therein, and where the first coil is disposed at least partially in the lumen. The first wire and the second wire may be co-wound to form a single coil.

Abstract: A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. The outer coil defines a lumen and the inner coil is disposed at least partially in the lumen. The vaso-occlusive device also includes an intermediate layer disposed between the inner coil and the outer coil, where the intermediate layer includes a biocompatible metal or a biocompatible, swellable polymer.

Abstract: A core wire of a delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature, includes a wire having a polyimide coating, with a polymer jacket disposed around the polyimide coating, and a hypotube disposed around the polymer jacket. The delivery wire assembly further comprises a delivery wire conduit including a coil disposed around the wire, wherein a proximal end of the coil is connected to a distal end of the hypotube. The polyimide coating may be enhanced with a nano-particle or micro-fiber ceramic, such as yttria-stabilized zirconia.

Abstract: An embolic coil introducer system that may include a catheter having a proximal end, a distal end, a lumen extending between the proximal and distal ends and a longitudinal axis, an embolic coil at least partially disposed in the lumen of the catheter, and a wire for moving the embolic coil at least partially disposed in the lumen of the catheter, the wire having a first diameter along a proximal region of the wire, wherein the catheter includes a locking mechanism that provides a friction fit between the catheter and the wire to hold the wire secure relative to the catheter in a first position when no force is applied to the wire and wherein the friction fit may be overcome by the application of a force to the wire to allow the wire to move relative to the catheter.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen, a plug at least partially seated in the conduit lumen and coupled to an interior surface of the coil portion so as to form a substantially fluid tight seal of the conduit lumen, and a core wire disposed in the conduit lumen, the core wire having a distal end extending through the plug and coupled to an occlusive device

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.

Abstract: An occlusive coil delivery system includes a delivery wire having a distal end coupled to an occlusive device via an electrolytically severable junction, and an electrical contact secured to a proximal end of the delivery wire, which has a non-linear configuration so as to strengthen a mechanical connection with the electrical contact and/or increase electrical conductivity with the electrical contact over a linear configuration. The configuration may be, by way of non-limiting examples, a “U” shape, a spiral, a knot, or a twisted wire. The electrical contact is a conductive material that substantially envelopes the proximal end configuration of the delivery wire.

Abstract: Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices comprising at least one polymer structure and methods of making and using these devices.

Abstract: Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices comprising at least one polymer structure and methods of making and using these devices.

Abstract: This is a device for occluding a space within the body. In particular, the device comprises an expandable member, an inner member and one or more stop elements. The devices may be placed in a desired site within a mammal to facilitate the formation of an occlusion.