Patents by Inventor Jimmy Kessler

Jimmy Kessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tubulin binding agents and corresponding prodrug constructs
    Publication number: 20060142252
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Application
    Filed: February 21, 2006
    Publication date: June 29, 2006
    Inventors: Kevin Pinney, Vani Mocharla, Zhi Chen, Charles Garner, Anjan Ghatak, Usha Ghatak, Mallinath Hadimani, Jimmy Kessler, James Dorsey, Klaus Edvardson, David Chaplin, Joseph Prezioso
  • Tubulin binding agents and corresponding prodrug constructs
    Patent number: 7001926
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: February 21, 2006
    Assignees: Oxigene, Inc., Baylor University
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Usha R. Ghatak, legal representative, Mallinath Hadimani, Jimmy Kessler, James M. Dorsey, Klaus Edvardsen, David J. Chaplin, Joseph Prezioso, Anjan Ghatak, deceased
  • Tubulin binding agents and corresponding prodrug constructs
    Publication number: 20040043969
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Application
    Filed: April 1, 2003
    Publication date: March 4, 2004
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Charles M. Garner, Anjan Ghatak, Mallinath Hadimani, Jimmy Kessler, James M. Dorsey, Klaus Edvardsen, David J. Chaplin, Joseph Prezioso, Usha R. Ghatak
  • Tubulin binding ligands and corresponding prodrug constructs
    Publication number: 20020055643
    Abstract: A diverse set of tubulin binding ligands have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, and phosphoramidates capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Application
    Filed: March 12, 2001
    Publication date: May 9, 2002
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Charles M. Garner, Anjan Ghatak, Mallinath Hadimani, Jimmy Kessler, James M. Dorsey