Abstract: Provided is a fast dissolving film composition comprising a medically active component as an active ingredient, in which the bitter taste of the active ingredient is masked and the fast dissolving film composition has a high content of 50% or higher. More particularly, provided is a pharmaceutical composition which comprises sildenafil or pharmaceutically acceptable salts thereof as an active ingredient, and which comprises a combination of a specific bitter taste masking agent to achieve masking of a bitter taste. Further, provided is a fast dissolving film composition which comprises a combination of a specific plasticizer to mask a bitter taste, and in which the physical properties of the high-content film are excellent.

Abstract: The present invention relates to an oral dissolving film formulation containing donepezil and a manufacturing method thereof and, more specifically, an oral dissolving film formulation for treating dementia including donepezil or acid addition salt thereof, cyclodextrin or derivatives thereof, alginic acid or salts thereof and a substrate for forming films, which is manufactured by adding a substrate for forming films to a liquid solution manufactured by firstly adding donepezil or acid addition salt thereof and secondly adding alginic acid or salts thereof to a solution in which cyclodextrin or derivatives thereof is melted, covering bitter taste and paralysis of donepezil.

Abstract: Provided is a fast dissolving film composition comprising a medically active component as an active ingredient, in which the bitter taste of the active ingredient is masked and the fast dissolving film composition has a high content of 50% or higher. More particularly, provided is a pharmaceutical composition which comprises sildenafil or pharmaceutically acceptable salts thereof as an active ingredient, and which comprises a combination of a specific bitter taste masking agent to achieve masking of a bitter taste. Further, provided is a fast dissolving film composition which comprises a combination of a specific plasticizer to mask a bitter taste, and in which the physical properties of the high-content film are excellent.