Abstract: Methods, network device and terminal device are disclosed time advance adjustment. A method comprises receiving a time advance, TA, command from a network device; determining a TA granularity or range; and determining a TA value based at least partly on the TA command and the TA granularity or range, wherein different numerologies are configured for at least two carriers and/or at least two bandwidth parts (BWPs) in one carrier, wherein the at least two carriers and/or the at least two BWPs serve the terminal device and/or the terminal device supports at least one numerology.

Abstract: The present disclosure provides a method (200) in a network node for coordination of Configured Scheduling, CS, among a plurality of backhaul links. The method (200) includes, for each of the plurality of backhaul links: determining (210) at least one CS-related parameter; and transmitting (220) to a scheduling IAB node of that backhaul link the at least one CS-related parameter.

Abstract: A technique for performing or providing random access, RA, to a radio access network using an unlicensed channel (400) is described. As to a method aspect of the technique, a first listen-before-talk (LBT) operation on the unlicensed channel is performed. The first LBT operation indicates that the channel is occupied at a beginning (412) of a RA resource (410) for transmitting a RA message signal (304). A second LBT operation on the unlicensed channel (400) indicates that the channel (400) is idle within a part (414) of the RA resource (410) for transmitting the RA message signal (304). The RA message signal (304) is transmitted in response to the second LBT operation.

Abstract: Various embodiments of the present disclosure provide a method for flow control. The method which may be performed by a first radio device comprises generating a first flow control message based at least in part on flow control information per flow control group. The method further comprises transmitting the first flow control message to a second radio device.

Abstract: Provided are small molecule inhibitors of the KRAS(G12D) mutant oncoprotein having the structural formula: and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.

Abstract: A method and an integrated access backhaul (IAB) node are disclosed for resource scheduling. According to an embodiment, the IAB node determines a first range of scheduling delay such that the first range is different from a second range of scheduling delay determined by a neighboring IAB node having a hop to the IAB node. The IAB node schedules an uplink transmission or downlink reception to occur within the first range.

Abstract: Provided are a layered oxide and a preparation method thereof, a positive electrode sheet, a secondary battery, a battery module, a battery pack and an electrical apparatus. The layered oxide includes an oxide with the general formula NaxMnyAaQbCcO2, where A is one or two of Fe and Ni; Q is one or more of transition metal elements containing 3d or 4d orbital electrons except Fe and Ni; C is one or two of Al and B, 0.66<x?1, 0.2?y?0.6, 0.3?a?0.6, 0<b?0.2, 0<c?0.1, and 1?b/c?100. The A element undergoes valence changes to provide charge compensation in a charge and discharge process, thereby improving the specific capacity of the layered oxide; the Q element and oxygen form a hybrid orbital, inhibiting irreversible oxygen losses and structure collapse of oxygen under a high voltage; the C element has a high ionic potential so as to effectively inhibit oxygen losses; and 1?b/c?100.

Abstract: A gain control method for a signal amplifier includes obtaining, by the signal amplifier, target information; determining, by the signal amplifier, a power adjustment parameter of the signal amplifier according to the target information, where the power adjustment parameter includes any one of the following: an amplification multiple-related parameter and a transmit power-related parameter; and adjusting, by the signal amplifier, a power parameter of the signal amplifier according to the power adjustment parameter, where the power parameter includes any one of the following: an amplification multiple and transmit power.

Abstract: A speaker module and a headset (100) are provided. The speaker module is used for the headset (100). The headset (100) includes a housing (1). The speaker module includes a first speaker unit (4a) and a second speaker unit (4b). An outer surface of a first diaphragm assembly (4a21) of the first speaker unit (4a) faces a first side, the second speaker unit (4b) is located on one side of a circumferential direction of the first speaker unit (4a), the second speaker unit (4b) emits sound toward the first side, and sound emission frequency of the second speaker unit (4b) is greater than sound emission frequency of the first speaker unit (4a).

Abstract: A transmitter (12) obtains data packets at a higher layer (16A) of a protocol stack (16), and duplicates each data packet at the higher layer (16A) to obtain duplicates of each data packet. The duplicates are transmitted on different respective channels from the higher layer (16A) to a lower layer (16B) of the protocol stack (16). The transmitter (12) generates different transport blocks to include data from the different respective channels, such that the duplicates of each data packet are conveyed by different transport blocks. For each transport block, the transmitter (12) transmits or does not transmit at least a part of the transport block within at least a part of a different respective transmission opportunity on a link (26) to a receiver (14) using unlicensed frequency spectrum (28), depending on whether or not a channel sensing procedure indicates the unlicensed frequency spectrum (28) is clear during that at least part of the transmission opportunity.

Abstract: Embodiments herein relates to a method performed by a UE for handling communication in a wireless communications network. The UE transmits a first indication in a PHR of a serving cell to a radio network node, wherein the first indication indicates presence of a first type of PH of a first carrier in the PHR of the serving cell, and wherein the first type is referring to an uplink RS transmission power. The PHR of the serving cell further comprises a second indication indicating presence of a PH of a second type of a second carrier of the serving cell, wherein the second type is referring to a user data transmission power.

Abstract: Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the disclosed compounds or compositions for treating and/or preventing diseases (e.g., inflammatory diseases, neurological diseases (e.g., Alzheimer's disease), infectious diseases (e.g., viral infections (e.g., infections caused by viral human hepatitis (e.g., hepatitis B), a flaviviridae family virus (e.g., a flavivims (e.g., Zika virus)))), and proliferative diseases (e.g., cancer (e.g., lung cancer, prostate cancer, skin cancer, thyroid cancer, pancreatic cancer, colorectal cancer, liver cancer, leukemia, or lymphoma)) in a subject. Provided are methods of inhibiting a protein kinase (e.g., MAP2K (e.g., MKK7)) in a subject. Also provided are methods of inhibiting MKK7 in a subject in need thereof.

Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., HCK, BTK, LYN) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating diseases (e.g., proliferative diseases) in a subject in need thereof).

Abstract: The present disclosure discloses a steel strip coiling temperature control method, a steel strip coiling temperature control device and a steel strip processing system, which relate to the technical field of steel strip production. The method comprises: seeking a corresponding speed compensation coefficient according to a target thickness of the steel strip and a target temperature parameter; seeking a corresponding speed gain coefficient from a second correspondence table according to a steel strip speed; correcting the steel strip speed based on the speed compensation coefficient and the speed gain coefficient to obtain a corrected steel strip speed; and adjusting a cooling efficiency of a laminar flow cooling apparatus according to the corrected steel strip speed.

Abstract: The present application provides bifunctional compounds of Formula X or an enantiomer, diastereomer, or stereoisomer thereof, or pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, which act as protein degradation inducing moieties for Bruton's tyrosine kinase (BTK). The present application also relates to methods for the targeted degradation of BTK through the use of bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to BTK which can be utilized in the treatment of disorders modulated by BTK.

Abstract: Disclosed is an integrated projection and illumination device. The integrated projection and illumination device includes a lamp housing, a mounting assembly, an illumination assembly and a projection assembly; and the mounting assembly includes a mounting disc, a mounting ring and clamping blocks, elastic members being arranged between the clamping blocks and the mounting ring, the mounting disc being provided with top surface connectors and an outer limiting edge, the outer limiting edge being capable of being clamped on the clamping blocks protruding out of the inner wall of the mounting ring, the mounting disc being further provided with pressing blocks, and the pressing blocks rotating along with the mounting disc and being capable of making contact with the clamping blocks and pressing the clamping blocks into the mounting ring during rotation. The present disclosure can be used for illumination and projection, and further features convenient dismounting and mounting.

Abstract: Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the disclosed compounds or compositions for treating and/or preventing diseases (e.g., inflammatory diseases, neurological diseases (e.g., Alzheimer's disease), infectious diseases (e.g., viral infections (e.g., infections caused by viral human hepatitis (e.g., hepatitis B), a flaviviridae family virus (e.g., a flavivims (e.g., Zika virus)))), and proliferative diseases (e.g., cancer (e.g., lung cancer, prostate cancer, skin cancer, thyroid cancer, pancreatic cancer, colorectal cancer, liver cancer, leukemia, or lymphoma)) in a subject. Provided are methods of inhibiting a protein kinase (e.g., MAP2K (e.g., MKK7)) in a subject. Also provided are methods of inhibiting MKK7 in a subject in need thereof.

Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., HCK, BTK, LYN, BLK, FRK) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating diseases (e.g., proliferative diseases) in a subject in need thereof).

Abstract: Disclosed is an integrated projection and illumination device. The integrated projection and illumination device includes a lamp housing, a mounting assembly, an illumination assembly and a projection assembly; and the mounting assembly includes a mounting disc, a mounting ring and clamping blocks, elastic members being arranged between the clamping blocks and the mounting ring, the mounting disc being provided with top surface connectors and an outer limiting edge, the outer limiting edge being capable of being clamped on the clamping blocks protruding out of the inner wall of the mounting ring, the mounting disc being further provided with pressing blocks, and the pressing blocks rotating along with the mounting disc and being capable of making contact with the clamping blocks and pressing the clamping blocks into the mounting ring during rotation. The present disclosure can be used for illumination and projection, and further features convenient dismounting and mounting.