Abstract: A copper plating structure and a package structure including the same are provided, and the copper plating structure includes at least one first copper layer and at least one second copper layer. The first copper layer includes a (111) crystal plane, wherein a proportion of the (111) crystal plane in each of the first copper layers is 36% to 100%. The second copper layer is located on the first copper layer and includes a non-(111) crystal plane or includes a (111) crystal plane and a non-(111) crystal plane, wherein a proportion of the (111) crystal plane in each of the second copper layers is 0% to 57%.

Abstract: The application provides a gRNA targeting miR-29b, an AAV8-CRISPR/Cas9 system and use thereof, belonging to the technical field of genetic engineering. The application provides a gRNA targeting miR-29b, which has a nucleotide sequence set forth in SEQ ID No.1. The gRNA shows strong specific editing ability to miR-29b at the cellular level, only has targeted editing effect on miR-29b without influence on miR-29a and miR-29c of the same family, and also shows higher editing efficiency, thus effectively inhibiting the expression of miR-29b. An AAV8-CRISPR/Cas9 system containing said gRNA targeting miR-29b. The use of gRNA targeting miR-29b or AAV8-CRISPR/Cas9 system in preparing drugs for treating muscle atrophy.

Abstract: The present application discloses a compound depicted by formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound provided in the present application can bind effectively to STING and has a good agonistic action on STING protein, and exhibits a good inhibitory effect on multiple tumors. Thus, the compound provided in the present application serves as a STING agonist and can be used for treating various related conditions. The compound provided in the present invention shows a very promising prospect for application thereof in the preparation of a medicament for treating a disease associated with STING activity (in particular, a medicament for treating an inflammatory disease, an allergic disease, an autoimmune disease, an infectious disease, a cancer or a precancerous syndrome) and in the preparation of an immune adjuvant, providing a novel option for clinically screening and/or preparing drugs for diseases associated with STING activity.

Abstract: Embodiments include a method, an electronic device, and a computer program product for storage management. According to one embodiment of the present disclosure, a method for storage management includes: determining at a kernel of a storage server whether a first system call related to a target file is initiated by a thread executed in the storage server, wherein the target file is a file targeted by an accessing operation executed by a client terminal with respect to a storage device; determining a first connection and a second connection that are associated with the target file if the first system call is initiated, wherein the first connection is a connection between the client terminal and the storage server, and the second connection is a connection between the storage server and the storage device; and causing the client terminal to access the target file via the first connection and the second connection.

Abstract: Techniques are disclosed for integrated booking of rooms and media resources, such as display devices. An example methodology implementing the techniques includes responsive to an activation of an access Uniform Resource Locator (URL) on a computing device, receiving information associated with a booking of a room and a display device, generating a token for accessing the display device and providing to the computing device the token and an address of the display device. The method also includes, responsive to receiving the token from the display device, authenticating the token and, responsive to authenticating the token, allowing use of the display device.

Abstract: The present disclosure relates to display screens and manufacturing methods of display screens. The display screen includes a packaged component, a non-display area including an effective package area adjacent to the packaged component, and a package shadow area located at a periphery of the effective package area. The package shadow area includes a supporting substrate defining a groove for disconnecting a thin film package structure formed on the support substrate. The thin film package structure is disconnected at the groove.

Abstract: Embodiments of the present disclosure relate to a method, an electronic device, and a computer program product for processing a machine learning model. The method includes: acquiring a computational graph, wherein nodes represent functions related to the machine learning model, and directed edges represent dependencies between the functions; determining multiple sequential portions of the computational graph, wherein the multiple portions will be executed sequentially and functions corresponding to nodes in each portion can be executed in parallel; and assigning, to the multiple portions, execution instances for executing functions corresponding to nodes in the corresponding portions, wherein the number of execution instances assigned to each portion is associated with time required to execute functions corresponding to nodes in the portion.

Abstract: A display panel inspection method and a apparatus are provided, and the method includes the steps of: capturing a grayscale image while a predetermined light source is irradiating a display panel, and the grayscale image including plural pixel electrode images corresponsive to plural pixel electrodes in the display panel respectively; obtaining a grayscale range of the respective pixel electrode image; calling a predetermined correspondence between a predetermined grayscale range and a pixel electrode type; and identifying the pixel electrode type of the respective pixel electrode image according to the predetermined correspondence and the grayscale range.

Abstract: A decoupled artificial intelligence model management architecture comprises a front-end component, a scheduler component and a back-end component configured to enable an open and dynamic system which accepts any models from any formats to be deployed on any target devices and to dynamically change scheduling of parallelism, parameter movements and computation executions across the target devices.

Abstract: In various embodiments, methods and systems for implementing distributed data object management are provided. The distributed data object management system includes a distributed storage system having a local metadata-consensus information store in and one or more remote metadata-consensus information stores. A metadata-consensus information store is configured to store metadata-consensus information. The metadata-consensus information corresponds to erasure coded fragments of a data object and instruct on how to manage the erasure coded fragments. The distributed storage system further includes a local data store and one or more remote data stores for the erasure coded fragments. The distributed data object management system includes a distributed data object manager for operations including, interface operations, configuration operations, write operations, read operations, delete operations, garbage collection operations and failure recovery operations.

Abstract: A pump body assembly, a compressor and an air conditioner are provided. The pump body assembly has a crankshaft, a main bearing, and a cylinder body. The crankshaft has a main shaft part and an eccentric part connected with the main shaft part. The main bearing has a hub part. The main shaft part extends through a through hole in the hub part. A first oil guide groove is formed in the hole wall of the through hole. A sliding vane slot and a center hole are formed in the cylinder body. The crankshaft extends through the center hole. The main bearing is located at the one side of the cylinder body. The crankshaft and the main bearing are in uniform contact with oil films at all positions. The abnormal wear of the main shaft part of the crankshaft can be reduced, and the service life of the compressor can be prolonged.

Abstract: An image of a receipt may be received by a service provider from a user device of a user. The receipt may be a record of a transaction between the user and a physical merchant. The service provider may extract text from the image and apply a predictive model trained on text data of historical receipts to the extracted text to identify keywords corresponding to items purchased in the transaction. The service provider may generate a shopping list for the user and/or may compare the keywords to descriptions of catalog items in an online catalog maintained by the service provider to identify catalog items that are the same or similar to the purchased items. The service provider may associate the catalog items with the user's account maintained by the service provider and generate a user interface to present on the user device that includes an indication of the catalog items.

Abstract: Techniques are disclosed for integrated booking of rooms and media resources, such as display devices. An example methodology implementing the techniques includes responsive to an activation of an access Uniform Resource Locator (URL) on a computing device, receiving information associated with a booking of a room and a display device, generating a token for accessing the display device and providing to the computing device the token and an address of the display device. The method also includes, responsive to receiving the token from the display device, authenticating the token and, responsive to authenticating the token, allowing use of the display device.

Abstract: The present invention provides methods of preparing a population of activated T cells by co-culturing T cells with dendritic cells loaded with a plurality of tumor antigen peptides. Also provided are methods of treating cancer in an individual using the activated T cells, pharmaceutical compositions and kits for cell-based cancer immunotherapy.

Abstract: A peak shaving control method for emergent source-grid coordination in case of a faulty sending-end power grid. The method includes: S1: evaluating dispatchability of a cluster virtual wind power unit; S2: developing a method for calculating a dispatchability index of the cluster virtual wind power unit; S3: analyzing a source-load peak-shaving resource strategy; and S4: distributing a control strategy for tie-line peak shaving. The present disclosure has the following beneficial effects: In the present disclosure, real-time dispatchability of wind power participating in real-time power balance is first analyzed, specific evaluation indexes and calculation methods are provided, and calculation examples are given for verification. Then, an optimized real-time dispatch strategy is provided based on demand-side response resources, and DC and AC tie-lines are coordinated for operation.

Abstract: An image sensor includes a photodiode array and a color filter array optically aligned with the photodiode array. The photodiode array includes a plurality of photodiodes disposed within respective portions of a semiconductor material. The color filter array includes a plurality of color filters arranged to form a plurality of tiled minimal repeating units. Each minimal repeating unit includes at least a first color filter with a red spectral photoresponse, a second color filter with a yellow spectral photoresponse, and a third color filter with a panchromatic spectral photoresponse.

Abstract: Disclosed are a rolling test device and a rolling test method. The rolling test device includes a test platform having a rolling surface for placing a test piece to be rolled; a rolling jig located on one side of the rolling surface; and a driving member connected to the rolling jig. A roller is connected to one end of the rolling jig towards the rolling surface, and after the roller is pressed against the rolling surface, the driving member drives the rolling jig to move on the rolling surface to drive the roller to perform a rolling test on the rolling surface.

Abstract: The present disclosure relates to methods and devices for obtaining path information of a data packet. One example method includes receiving, by a network device, a data packet transmitted in a network, and obtaining, by the network device, path information of the data packet from a source end to a destination end, where the path information is a total hop count of routers passed through by the data packet from the source end to the destination end or a latency of the data packet from the source end to the destination end.

Abstract: A large grain quasi-single-crystal film and a manufacturing method thereof are provided. The metal film having the <111> preferred orientation on its surface is subjected to mechanical tensile force to make the arrangement of crystal grains more ordered. The metal film is grown into a film with large crystal grains having an average diameter of over 500 microns by annealing at a temperature below the recrystallization temperature, thereby obtaining a large grain quasi-single-crystal film having the preferred directions of three axes. The large grain quasi-single-crystal film has a <110> preferred orientation along the tensile direction and a <211> preferred orientation along the direction vertical to the tensile force, and maintains a <111> preferred orientation on its top surface. The present invention can be used to produce highly anisotropic large-area quasi-single-crystal films, and can also be applied to grow 2-dimensional materials or develop anisotropic structures.

Abstract: Provided is a method of treating a cancer in an individual using activated T cells or PBMCs induced by antigen presenting cells (such as dendritic cells) loaded with a plurality of tumor antigen peptides. The method may further comprise administration of the antigen presenting cells loaded with the plurality of tumor antigen peptides to the individual. The methods may be used singly or in combination with an immune checkpoint inhibitor. Also provided are precision therapy methods customized for the individual using neoantigen peptides or based on the mutation load in the tumor of the individual, methods of preparing the activated T cells, methods of monitoring the treatment, methods of cloning tumor-specific T cell receptors, an isolated population of cells comprising the activated T cells, and compositions and kits useful for cancer immunotherapy.