Patents by Inventor Jin-Mu YI

Jin-Mu YI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for prevention, alleviation, or treatment of peripheral neuropathy comprising Lithospermi Radix extract as an effective component
    Patent number: 10517913
    Abstract: A composition comprising a Lithospermi Radix extract as an effective component prevents, alleviates, or treats peripheral neuropathy, in particular, peripheral neuropathy induced by an anti-cancer agent (i.e., chemotherapy-induced peripheral neuropathy). A method for preventing or treating peripheral neuropathy includes administering to a subject in need thereof the composition. The Lithospermi Radix extract can relieve the suppressed growth of neurites caused by an anti-cancer agent while neither inducing any cytotoxicity in normal cells nor changing the unique cytotoxic potential of an anti-cancer agent in human cancer cells. In addition, the Lithospermi Radix extract can efficiently lower the enhanced sensitivity to painful stimuli in peripheral neuropathic animals induced by an anti-cancer agent. Thus, the Lithospermi Radix extract can be advantageously used as an effective component of a composition for prevention, alleviation, or treatment of chemotherapy-induced peripheral neuropathy.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: December 31, 2019
    Assignee: KOREA INSTITUTE OF ORIENTAL MEDICINE
    Inventors: No Soo Kim, Jong-Shik Park, Jin-Mu Yi, You Jin Lee, Eun-Sang Cho, Jinhee Kim, Chae Jun Lim, Ok-Sun Bang, Youngah Kim
  • COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF PERIPHERAL NEUROPATHY COMPRISING LITHOSPERMI RADIX EXTRACT AS AN EFFECTIVE COMPONENT
    Publication number: 20180303889
    Abstract: A composition comprising a Lithospermi Radix extract as an effective component prevents, alleviates, or treats peripheral neuropathy, in particular, peripheral neuropathy induced by an anti-cancer agent (i.e., chemotherapy-induced peripheral neuropathy). A method for preventing or treating peripheral neuropathy includes administering to a subject in need thereof the composition. The Lithospermi Radix extract can relieve the suppressed growth of neurites caused by an anti-cancer agent while neither inducing any cytotoxicity in normal cells nor changing the unique cytotoxic potential of an anti-cancer agent in human cancer cells. In addition, the Lithospermi Radix extract can efficiently lower the enhanced sensitivity to painful stimuli in peripheral neuropathic animals induced by an anti-cancer agent. Thus, the Lithospermi Radix extract can be advantageously used as an effective component of a composition for prevention, alleviation, or treatment of chemotherapy-induced peripheral neuropathy.
    Type: Application
    Filed: September 30, 2015
    Publication date: October 25, 2018
    Inventors: No Soo KIM, Jong-Shik PARK, Jin-Mu YI, You Jin LEE, Eun-Sang CHO, Jinhee KIM, Chae Jun LIM, Ok-Sun BANG, Youngah KIM