Abstract: Most automatic cuff blood pressure (BP) measurement devices are based on oscillometry. These devices estimate BP from the envelopes of the cuff pressure oscillations using fixed ratios. The values of the fixed ratios represent population averages, so the devices may be accurate only in subjects with normal BP levels. A patient-specific oscillometric BP measurement method was developed. The idea was to represent the cuff pressure oscillation envelopes with a physiologic model and then estimate the patient-specific parameters of the model, which includes BP levels, by optimally fitting it to the envelopes.

Abstract: Systems and methods for monitoring and/or controlling a cardiovascular system of a subject are disclosed. In some aspects, the method includes acquiring cardiovascular data from a subject, analyzing the cardiovascular data to determine a time trajectory for at least one cardiovascular parameter, and determining, using the time trajectory, a likelihood that the at least one cardiovascular parameter exceeds a threshold at one or more pre-determined time points. The method also includes determining a future cardiovascular state of the subject using the determined likelihood, and generating a report indicative of the future cardiovascular state of the subject. The method may also include estimating a dose response associated with at least one administered pharmaceutical agent for at least one cardiovascular parameter, and controlling the cardiovascular state of the subject at one or more pre-determined time points using the estimated dose response.

Abstract: A method is provided for determining blood pressure for a subject using a sphygmomanometer. The method includes: measuring an oscillometric cuff pressure waveform of the subject using the sphygmomanometer; representing the measured waveform with a physical model accounting for mechanics of the cuff, an artery and coupling between the cuff and the artery; determining the model unknowns from the measured waveform; and determining blood pressure for the subject using the determined model.

Abstract: Methods and a computer program product for using a circulatory measurement on an extremity of a particular subject to derive an aortic blood pressure for that subject. A model is constructed that maps a peripheral cardiovascular waveform to a central cardiovascular waveform on the basis of a plurality of model parameters. A time record is obtained using a non-invasive blood pressure sensor disposed at a solitary position periphery of the cardiovascular system of a subject. The time record is then transformed to obtain a plurality of test central blood pressure waves, with a single test central blood pressure wave is based on each of a plurality of sets of values of the model parameters. An optimum set of values of the model parameters is then selected, based on a specified criterion applied to the plurality of test central blood pressure waves, so that the aortic circulatory waveform of the subject can be obtained.

Abstract: An apparatus for controlling vehicle stability includes a pressure calculator calculating a brake pressure. In one embodiment, the calculated brake pressure is calculated based on a yaw rate signal input from a yaw rate sensor. In other embodiments, the calculated brake pressure is further calculated on the basis of signals input from a steering angle sensor, a lateral acceleration sensor, a vehicle speeds sensor, and a master brake pressure sensor. A method for controlling vehicle stability is also provided. The method and apparatus enhances stability and reliability during vehicle driving.

Abstract: An apparatus for controlling vehicle stability includes a virtual pressure calculator calculating a virtual brake pressure. In one embodiment, the virtual brake pressure is calculated based on a yaw rate signal input from a yaw rate sensor. In other embodiments, the virtual brake pressure is further calculated on the basis of signals input from a steering angle sensor, a lateral acceleration sensor, a vehicle speeds sensor, and a master brake pressure sensor. A method for controlling vehicle stability is also provided. The method and apparatus enhances stability and reliability during vehicle driving.