Abstract: Devices, and methods for the use of same, for collecting and assaying a biological fluid in a single step. One method provides means to control and direct the flow of a sample of the biological fluid directly onto an assay test strip by disposing the assay test strip within a flow control channel in which the internal ambient pressure is maintained in substantial equilibrium with the ambient pressure outside of the flow control channel, such that essentially no pressure gradient is formed within the flow control channel. The devices include the flow control channel, at least one assay test strip and a fluid sample collection container, such as a urine cup, for insertion of the flow control channel therein.

Abstract: The present invention provides a test apparatus and methods for the detection of pharmacologically active compounds from body fluids, in particular from saliva. The invention test apparatus prevents the aqueous solution of the analyte(s) from flowing underneath the nitrocellulose membrane and ensures that even the smallest amounts of the aqueous solution of the analyte(s) are collected and pulled into and through the test strip by capillary action. The invention test apparatus provides sensible and rapid detection of the analyte(s) in the aqueous solution.

Abstract: The present invention relates to replaceable dental brush units useful in an electric toothbrush. In particular, the invention provides for a replaceable dental brush unit useful in an electric toothbrush that uses gear links for connecting and driving motions of bristle head by motors.

Abstract: Devices, and methods for the use of same, for collecting and assaying a biological fluid in a single step. One method provides means to control and direct the flow of a sample of the biological fluid directly onto an assay test strip by disposing the assay test strip within a flow control channel in which the internal ambient pressure is maintained in substantial equilibrium with the ambient pressure outside of the flow control channel, such that essentially no pressure gradient is formed within the flow control channel. The devices include the flow control channel, at least one assay test strip and a fluid sample collection container, such as a urine cup, for insertion of the flow control channel therein.

Abstract: An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for contemporaneously assaying the sample for the presence or absence of multiple analytes, such as drugs of abuse. The device is composed of a housing having separate slots therein for insertion of one or more analyte test strips, one end of which protrudes from the housing, and one or more units of a sample integrity monitoring system. The device may be used in dipstick or cassette form. An analyte sample separator for division of sample and retention of uncontaminated sample for further testing is also provided. The analyte test strips and sample integrity monitoring system are replaceable, so that the panel of analytes and of sample condition parameters tested can be customized.

Abstract: The present invention relates to replaceable dental brush units useful in an electric toothbrush. In particular, the invention provides for a replaceable dental brush unit useful in an electric toothbrush that uses gear links for connecting and driving motions of bristle head by motors.

Abstract: Test strip device for accepting a liquid sample and forming an even fluid front across the test strip. When the sample is applied to a contacting surface, it runs down the surface where it collects between the contacting surface and a slope surface. As the sample collects, it evenly reaches fluid flow contact with an absorbent membrane. As a result, the sample forms an even fluid front across the membrane, improving the performance of the test strip device. Methods for using the device to accept a sample and to detect an analyte in the liquid sample are also provided.

Abstract: An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for contemporaneously assaying the sample for the presence or absence of multiple analytes, such as drugs of abuse. The device is composed of a housing having separate slots therein for insertion of one or more analyte test strips, one end of which protrudes from the housing, and one or more units of a sample integrity monitoring system. The device may be used in dipstick or cassette form. An analyte sample separator for division of sample and retention of uncontaminated sample for further testing is also provided. The analyte test strips and sample integrity monitoring system are replaceable, so that the panel of analytes and of sample condition parameters tested can be customized.

Abstract: The present invention provides an analytical test device for conducting assays of biological fluids. Methods for carrying out the assays with the disclosed analytical test devices are also provided.

Abstract: The present invention provides an analytical test device for conducting assays of biological fluids. Methods for carrying out the assays with the disclosed analytical test device are also provided.

Abstract: The invention consists of devices for use in assaying fluid test samples for analyte of interest wherein the samples contain or are suspected of containing cells and cellular components. The devices of the invention each include a hydrophilic cell trap for separation of the cellular fraction from the noncellular fraction of the test sample. The latter fraction migrates through porous, absorbent or bibulous membranes of the device which are impregnated with reagents in at least three separate zones comprising a dye zone, a test zone and a control zone. Formation of a distinctive visual pattern in the control zone indicates that the test was competently performed while formation or relative intensity of the visual pattern in the test zone indicates presence or absence of analyte in the test sample.