Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: Disclosed are an oxidizing electrode, a water electrolysis device including the same and a method for manufacturing the same. According to exemplary embodiments of the present disclosure, there is provided an oxidizing electrode with improved performance at low loadings of noble metals, especially, ruthenium (Ru) and iridium oxide, in which a ruthenium (Ru) layer and an iridium oxide layer formed on a substrate by electrodeposition in a sequential order are supported by electrochemical reaction rather than physical bonding.

Abstract: A biologically active cyclic synthetic peptide analog having an amino acid sequence similar to that of native epidermal growth factor between amino acids 32-48 is revealed. The peptide has been found to mimic certain biological activities of intact native epidermal growth factor (EGF). The EGF peptide analogs of the present invention include at least one sulfhydryl bond between two cysteines of the peptide containing block termini. The peptides comprise the end of the B-loop and the C-loop characteristic of the native form of the epidermal growth factor peptide. The biological activity of the peptide provides for methods of using the peptide as an agent in wound healing and also in cancer therapy. More particularly, the described peptides are used in cancer therapeutic applications and in the promotion of wound healing, especially burn wounds and peptic ulcer disease. Methods of preparing and using the described bioactive EGF analog peptides are also disclosed.

Abstract: A specialty eyewear device including an optical frame that carries a pair of highly reflective surfaces that permit a wearer to experience an angular offset between the direct line of vision and the effective line of vision. No refraction occurs in the performance of the device, and no image reversal takes place. Modifications of the invention allow for certain angular adjustments in the device which can both change the actual angular offset which occurs between direct and effective line of vision, and permits angular rotation of a given angular offset.

Abstract: A robot manipulator uses multiple robot arms to grasp and move an object. The object is moved by the coordinated motion of the arms. Because of inaccuracies in the coordinated motion of the arms due to mechanical inaccuracies or to imperfections in the model used by the controller to evaluate the interaction of the arms with the environment, the actual motion of the arms may be slightly uncoordinated. This may result in the application of unwanted forces to the object which may distort or break the object, the arms, or both. A multiarm accommodation arrangement evaluates the forces applied by the arms to the object to determine the net forces, and generates position accommodation signals which are summed with the several mutually coordinated arm control signals to tend to cause the forces applied to the object to be zero or a desired finite value. In a particular embodiment of the invention, an outer loop provides position accommodation to control forces applied by the object to an external load.