Abstract: This disclosure is directed toward an integrated switching and routing security device that provides zone-based security directly between layer two (L2) interfaces of L2 bridge domains and/or layer three (L3) interfaces of L3 routing instances within the security device. The integrated switching and routing security device supports both switching and routing functionalities for packets on L2 and L3 interfaces, and supports security within and between L2 bridge domains and L3 routing instances. The integrated switching and routing security device configures L2 security zones for one or more L2 interfaces and configures L3 security zones for one or more L3 interfaces. The integrated switching and routing security device then applies security policies to incoming packets according to the L2 security zones and/or the L3 security zones associated with the incoming interface and an outgoing interface for the packets to provide end-to-end security within the security device.

Abstract: A method performed by a network system having a plurality of processing units implemented using a plurality of respective virtual machines, includes: receiving a first packet at a first virtual machine of the plurality of virtual machines, wherein the first virtual machine is configured to receive the first packet from a network through an interface and has session processing capability; calculating a first value using a mathematical algorithm based on one or more information regarding the first packet; and using the calculated first value to identify a second virtual machine of the plurality of virtual machines in the network system.

Abstract: Deasphalted residual oil (DAO) and the aromatics-rich extract that is derived from DAO have low polycyclic aromatics contents, relatively low aniline points, and high flash points. They form blending stocks that improve properties of mixed feedstocks to consistently produce environmentally qualified rubber processing oil (RPO) by extraction under low solvent-to-oil ratios and moderate extraction temperatures. Distilling a petroleum crude oil under atmospheric pressure generates a bottom residual oil which is then subject to vacuum distillation to yield a bottom residual oil. DAO is produced by removing the asphalt from the vacuum bottom residual oil through extraction with light paraffinic solvent. The extract of DAO is a co-product in the production of the bright stock of the lubricating oil through extraction. The feedstock is mixed with the extract from a petroleum fraction boiling in lube oil range.

Abstract: A method performed by a network appliance having a plurality of application processing units, includes: receiving a first packet at the network appliance; calculating a first value using a mathematical algorithm based on one or more information regarding the first packet; and using the calculated first value to identify a first application processing unit of the plurality of application processing units in the network appliance. A network appliance includes: a plurality of processing units that are communicatively connected to each other; wherein a first processing unit of the plurality of processing units is configured for: calculating a first value using a mathematical algorithm based on one or more information regarding a first packet; and using the calculated first value to identify a second processing unit of the plurality of processing units.

Abstract: Deasphalted residual oil (DAO) and the aromatics-rich extract that is derived from DAO have low polycyclic aromatics contents, relatively low aniline points, and high flash points. They form blending stocks that improve properties of mixed feedstocks to consistently produce environmentally qualified rubber processing oil (RPO) by extraction under low solvent-to-oil ratios and moderate extraction temperatures. Distilling a petroleum crude oil under atmospheric pressure generates a bottom residual oil which is then subject to vacuum distillation to yield a bottom residual oil. DAO is produced by removing the asphalt from the vacuum bottom residual oil through extraction with light paraffinic solvent. The extract of DAO is a co-product in the production of the bright stock of the lubricating oil through extraction. The feedstock is mixed with the extract from a petroleum fraction boiling in lube oil range.

Abstract: In general, techniques are described for dynamically managing weighted queues. In accordance with the techniques, a network security device comprises a queue management module that assigns, for each queue of a plurality of queues, a quota desirable to a user that a processor of the network security device consumes to service each queue. The queue management module determines, based on the desirable quotas, a queue weight for each queue and computes. Based on the computation, the queue management module dynamically adjusts one or more of the weights such that subsequent amounts of processing time actually required to process the number of packets defined by each of the queue weights more accurately reflects the desirable quotas assigned to each of the queues. The network device outputs the number of packets in accordance with the adjusted weights.

Abstract: A method may be performed by a device in a network, the device including multiple security process units (SPUs). The method includes receiving a packet over the network, the packet including a media access control (MAC) address, and assigning one SPU as the MAC address owner. The method also includes sending information about the MAC address to other SPUs within the device, storing the MAC address in a MAC table within each SPU, and initiating a MAC age query to confirm the MAC address has timed out among all SPUs. The MAC age query is passed via a logical ring of the SPUs beginning with the MAC address owner. If the MAC address is aged out at each SPU, the MAC address is deleted from each MAC table. If the MAC entry is still active, a different SPU is assigned as the MAC address owner.

Abstract: MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression and which play important roles in many cell types, including as described herein, the pancreatic ?-cell. Glucagon like peptide-1 (GLP-1), a hormone released from intestinal L-cells following meal intake, exerts pleiotropic effects on ?-cell function including raising intracellular cAMP levels and now represents an important therapy for type 2 diabetes. Expression of miR-132 and miR212 is upregulated by CREB protein in response increased cAMP levels in the cell; therefore, methods for detecting and evaluating ?-cell engagement by GLP-1 receptor agonists by monitoring miR-132 and miR-212 expression in a subject is described. The methods herein are particularly useful in the context of longitudinal clinical trials, such as those designed for testing the durability of any single or combination therapy in type 2 diabetes populations.

Abstract: A method is disclosed for providing security to a client-to-client communication. The method includes authenticating a first client and a second client with an access point device, transmitting the packet to the security device and modifying a destination media access control (MAC) address of a packet from the first client to a MAC address of a security device for a first network. The packet contains a destination internet protocol (IP) address of the second client. The access point device and the first and second clients belong to the first network. The security device is located between the first network and a second network.

Abstract: The present application features the use of the somatostatin subtype 3 receptor (SST3) as a target for affecting insulin secretion and for diagnosing diabetes related disorders. Glucose stimulated insulin secretion was found to be stimulated by knocking down expression of SST3 and through the use of a SST3 selective antagonist.

Abstract: An integrated security switch and related method for managing connectivity and security among networks. The integrated security switch includes a security function connectable with a first network and at least one switching function connectable with a second network. A common management interface driven by both command line interface and graphic user interface protocols manages the switching function via a management path dedicated between the security function and the switching function. The common management interface enables secure switching of traffic to flow via a traffic path dedicated between the switching function and the security function. Typically, the traffic is a flow of data between the Internet and a group of networked users such as a wide area network.

Abstract: An integrated security switch and related method for managing connectivity and security among networks. The integrated security switch includes a security function connectable with a first network and at least one switching function connectable with a second network. A common management interface driven by both command line interface and graphic user interface protocols manages the switching function via a management path dedicated between the security function and the switching function. The common management interface enables secure switching of traffic to flow via a traffic path dedicated between the switching function and the security function. Typically, the traffic is a flow of data between the Internet and a group of networked users such as a wide area network.

Abstract: The present application features the use of the somatostatin subtype 3 receptor (SST3) as a target for affecting insulin secretion and for diagnosing diabetes related disorders. Glucose stimulated insulin secretion was found to be stimulated by knocking down expression of SST3 and through the use of a SST3 selective antagonist.

Abstract: An integrated security switch and related method for managing connectivity and security among networks. The integrated security switch includes a security function connectable with a first network and at least one switching function connectable with a second network. A common management interface driven by both command line interface and graphic user interface protocols manages the switching function via a management path dedicated between the security function and the switching function. The common management interface enables secure switching of traffic to flow via a traffic path dedicated between the switching function and the security function. Typically, the traffic is a flow of data between the Internet and a group of networked users such as a wide area network.

Abstract: Genes, nucleic acids, proteins, antibodies, marker sets, and arrays for the atherosclerosis susceptibility locus (ATHS) are provided. Methods of detecting atherosclerosis susceptibility and modulating cholesterol phenotype in cells are also provided.

Abstract: Genes, nucleic acids, proteins, antibodies, marker sets, and arrays are provided. Methods of detecting conditions associated with elevated cholesterol and lipid, as well as during adipogenesis, are also provided.

Abstract: Polynucleotides, proteins, antibodies, labeled probes, marker sets, and arrays related to secreted and cell surface proteins that are altered in response to cholesterol are provided. Methods of detecting alterations in secreted and cell surface proteins in response to alterations in cholesterol levels (exposure), modulating cholesterol phenotype in cells and for treating a subject with adverse effects of altered levels of cholesterol, e.g., elevated or high levels of cholesterol, are also provided.