Abstract: The present invention provides an immunogenic composition comprising a Streptococcus pneumoniae polysaccharide-protein conjugate, comprising a capsular polysaccharide derived from one or more selected from the group consisting of serotypes 1, 2, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F, derived from Streptococcus pneumoniae; and one or 2 or more of carrier proteins conjugated to the respective capsular polysaccharide, and method of preparation thereof. Through one example of the present invention, an immunogenic composition for preventing or treating pneumococcal infection can be provided.

Abstract: Disclosed is a polytrimethylene terephtalate conjugate fiber having high self-crimpability, which is prepared by conjugate-spinning two types of polytrimethylene terephtalates having different intrinsic viscosities in which a difference between the intrinsic viscosities ranges from 0.05 to 0.15 into a side-by-side fiber. Also, the polytrimethylene terephtalate conjugate fiber prepared by the conjugate-spinning undergoes a false twisting process, leading to development of three-dimensional high self crimpability and sufficient bulky property in the resulting fiber.