Abstract: The present disclosure relates to a novel-peptide-based anticancer immunotherapeutic agent, and to use, as an anticancer immunotherapeutic agent, of melittin, a variant thereof, analogues thereof, or a conjugate in which a drug is linked thereto. The melittin, the variant thereof or the analogues thereof, of the present disclosure, specifically bind to ITGB2, which is expressed on the cell membrane of M2 tumor-associated macrophages, so as to kill the M2 tumor-associated macrophages, and a conjugate in which a pro-apoptotic peptide or an anticancer drug is conjugated as a drug to the melittin, the variant thereof, or the analogues thereof remarkably increases apoptotic effects of the M2 tumor-associated macrophages, and thus can be used as an anticancer composition for suppressing tumor growth and metastasis.

Abstract: A detection mode control circuit, including a morphological detection module (100) connected to a morphological detection probe (500), where the morphological detection module (100) is configured to generate a morphological detection control signal according to a user instruction or a system setting; further including an elasticity detection module (200) connected to a switch module (300) and configured to generate an elasticity detection control signal and a second control signal according to the user instruction or the system setting; where the switch module (300) is connected to a compound probe (600) and configured to receive the morphological detection control signal, the elasticity detection control signal and the second control signal, and control the compound probe (600) to perform morphological detection according to the second control signal or control the compound probe (600) to perform elasticity detection according to the second control signal.

Abstract: A hydrogenation catalyst contains a hydrogenation catalyst carrier and an active hydrogenation component. The active hydrogenation component includes a Group VIB metal sulfide and a Group VIII metal compound, and the molar proportion of a substance of the Group VIII metal compound that interacts with the Group VIB metal sulfide to the total amount of the Group VIII metal compound is 60-100%. The hydrogenation catalyst has a higher active metal sulfurizing degree and a higher number of type II active centers, and can be applied to the hydrogenation treatment process of oil products such as distillate oils and residual oils.

Abstract: A data processing method and apparatus, a device and a storage medium, where the method includes: obtaining first target result data according to an original ultrasonic echo signal, where the first target result data includes a related parameter of a detected object; performing feature extraction on the first target result data using a pre-trained feature extraction model to obtain second target result data; and performing corresponding processing on the detected object based on the second target result data. By performing feature extraction on the related parameter of the detected object using the pre-trained feature extraction model to obtain the second target result data, and further performing corresponding processing on the detected object based on the second target result data, thereby improving accuracy of judging the state of the detected object effectively.

Abstract: The present disclosure relates to an optical fiber image correction method, device and computer readable storage medium. The method comprises: obtaining a current optical fiber image and a central reference position of an optical fiber; in the current optical fiber image, correcting a central position of each optical fiber unit in the current optical fiber image according to a position difference condition between the central reference position of the optical fiber and a target position determined based on gray values in a neighboring range of the central reference position of the optical fiber; correcting brightness of the current optical fiber image that has completed a position correction according to a currently determined brightness correction coefficient.

Abstract: An improved typelog alignment for automated or interactive geosteering may use multi-stage penalized optimization.

Abstract: The present disclosure relates to an optical fiber image correction method, device and computer readable storage medium. The method comprises: obtaining a current optical fiber image and a central reference position of an optical fiber; in the current optical fiber image, correcting a central position of each optical fiber unit in the current optical fiber image according to a position difference condition between the central reference position of the optical fiber and a target position determined based on gray values in a neighboring range of the central reference position of the optical fiber; correcting brightness of the current optical fiber image that has completed a position correction according to a currently determined brightness correction coefficient.

Abstract: The present disclosure provides a substrate processing apparatus and a substrate processing method, which control an internal temperature of a process tube in a substrate processing process.

Abstract: Disclosed are a method, apparatus and device for calculating signal attenuation, and a computer-readable storage medium. The method comprises: receiving an ultrasound signal by an ultrasonic imaging system, performing signal recovery operation on the ultrasound signal propagating in a tissue to obtain a recovered ultrasound signal; determining a type of the recovered ultrasound signal, and calculating attenuation information of the recovered ultrasound signal by adopting a calculation mode corresponding to the type according to the type of the recovered ultrasound signal. As such, the signal attenuation calculation flow is simplified, thereby enabling use of commercial probes therein, bringing convenience in operation, and increasing applicability. Accuracy and efficiency of attenuation calculation can be improved by means of performing signal recovery on an obtained ultrasonic signal and then performing attenuation calculation thereon.

Abstract: Provided are method, apparatus and device for measuring a thickness of a subcutaneous tissue, and a computer-readable storage medium. The method includes: emitting ultrasonic detection waves inwards from a skin surface, and acquiring ultrasonic echo signals of the ultrasonic detection waves; determining, according to ultrasonic parameter values of the ultrasonic echo signals and a characteristic parameter threshold of a subcutaneous tissue, the moment the ultrasonic echo signals from the boundary of the subcutaneous tissue are received; and calculating a thickness of the subcutaneous tissue according to the moment the ultrasonic echo signals from the boundary of the subcutaneous tissue are received, thereby enabling a precise measure of the thickness of the subcutaneous tissue.

Abstract: The present invention discloses a sunflower seed composition rich in pleasant prohormone and anti-depression application thereof, and belongs to the field of extraction and application of natural products. Sunflower seeds used in the composition provided by the present invention are rich in tryptophan and have a high tryptophan/neutral amino acid ratio. After defatting treatment and chlorogenic acid removal treatment, and added part can increase a glycemic index. Glucose and vitamins for promoting absorption conversion of tryptophan and ?-3 fatty acids beneficial to nervous activities enable the sunflower seeds to have a better anti-depression effect. The sunflower seed composition of the present invention can improve concentrations of a monoamine neurotransmitter (serotonin) and dopamine in the brain and has a very good effect of ameliorating and treating depression.

Abstract: An ultrasound generation device includes: an ultrasound generator for irradiating the skin with ultrasound energy; and a controller for controlling the operation of the ultrasound generator. The controller controls the ultrasound generator so that the ultrasound generator applies a specific ultrasound energy corresponding to at least one of fat increase, fat reduction, of elastic fiber increase in a skin layer.

Abstract: The present invention relates to a method, a composition, and a kit for preoperative prediction of prognosis after liver cancer surgery at an early stage by detecting, in a blood sample obtained from a liver cancer patient prior to surgery, an SORD marker, or an SORD marker together with an AFP marker.

Abstract: A display device and a method of manufacturing the same are provided. A display device includes: a substrate including a plurality of pixels; a first electrode and a second electrode spaced apart from each other on the substrate; a light emitting element located between the first electrode and the second electrode; and a conductive pattern on the light emitting element. The light emitting element includes a first semiconductor layer, a second semiconductor layer, and an active layer between the first semiconductor layer and the second semiconductor layer, and the conductive pattern overlaps the active layer and does not overlap the first semiconductor layer or the second semiconductor layer.

Abstract: An electrolysis device, electrolysis system, and electrolysis method for alternating current induction power supply are provided. The electrolysis device includes at least one group of magnetic circuits and an electrolytic cell. The magnetic circuit has a magnetic core on which an electromagnetic coil is wound, the magnetic core being provided outside the electrolytic cell. The magnetic circuits are used for using an alternating current power source to generate a rotating magnetic field surrounding the electrolytic cell, the rotating magnetic field acting on an electrolyte in the electrolytic cell to generate an induction direct current, such that the electrolyte is electrolyzed. According to the electrolysis device, the electrolytic cell generates the induction direct current directly by means of an alternating current, such that alternating current and direct current conversion links are reduced, and energy loss caused by energy conversion is reduced.

Abstract: An ultrasonic signal processing method and apparatus (30), a computer device (50) and a storage medium. The method includes: acquiring a target ultrasonic signal of a dynamic broadband corresponding to target tissue (101); determining, according to the target ultrasonic signal, an acoustic characteristic parameter of the target tissue (102); performing assessment processing to the target tissue according to the acoustic characteristic parameter of the target tissue (103). The acoustic characteristic parameter of the target tissue is determined according to the target ultrasonic signal of the dynamic broadband corresponding to the target tissue, and the assessment is performed to the target tissue based on the acoustic characteristic parameter of the target tissue, and ultrasonic signals of the target tissue at multiple frequencies are comprehensively considered, so that signal components are varied, thereby improving accuracy of the assessment to the target tissue.

Abstract: The disclosure discloses application of breast milk-derived Lactobacillus reuteri in regulating the maternal and infant immune function, belonging to the fields of microbiological technology and food science. The disclosure provides the effects of Lactobacillus reuteri Fn041 in enhancing the immunity of pregnant or lactating women and infants, i.e., enhancing the mucosal barrier, promoting the production of intestinal antibacterial peptides and IgA, promoting the development of the immune system of infants, preventing pathogen infection and reducing the incidence of allergic diseases.

Abstract: Disclosed are a dual modulator of mGluR5 and 5-HT2AR (5-HT2A receptor), and use thereof. More specifically, disclosed are a compound which acts as modulator of mGluR5 and an antagonist of 5-HT2AR at the same time, and use thereof as therapeutic agent for pain.

Abstract: Disclosed are a method, an apparatus and a device for locating a region of interest of a tissue, and a storage medium. The method comprising: acquiring ultrasonic echo signals from a detected region; identifying interfering regions and a region of interest in the detected region according to ultrasonic parameter values of the ultrasonic echo signals; judging whether the sizes of the interfering regions meet a preset condition or not; and if the sizes of the interfering regions meet the preset condition, removing interfering signals corresponding to the interfering regions from the ultrasonic echo signals. As such, the interfering signals may be removed while the interfering regions are small.

Abstract: A method for quantifying viscoelasticity of a medium includes: obtaining a position-time graph of vibration propagation after the medium is subjected to a vibration excitation, determining an angle with maximum signal energy in the position-time graph by using angle projection, where the angle with the maximum signal energy corresponds to a slope of the position-time graph and the slope of the position-time graph is the propagation velocity of the vibration in the medium. Since the propagation velocity of the vibration in the medium is related to the viscoelasticity of the medium, a viscoelasticity parameter of the medium can be quantitatively calculated after the slope of the position-time graph is obtained. The method does not need to select a feature point from the position-time graph to calculate the slope of the position-time graph, and can efficiently and accurately quantifies viscoelasticity of the medium.