Abstract: The present invention relates to a nucleic acid molecule simultaneously inhibiting the expression of mTOR gene and STAT3 gene, and an anticancer pharmaceutical composition comprising the same. More specifically, base-paired siRNA or shRNA of the present invention, designed to simultaneously inhibit the expression of cancer-related mTOR gene and STAT3 gene in order to surmount the problem that siRNA or shRNA does not achieve high therapeutic effects due to the target specificity thereof, has the effect of promoting the death of cancer cells. In addition, the nucleic acid has the effect of synergistically enhancing the apoptosis of cancer cells when used in combination with an anticancer agent, finding useful applications as an anticancer composition or anticancer aid against various carcinomas.

Abstract: Provided is a pharmaceutical composition for preventing or treating neuronal diseases comprising, as an active ingredient, an exon 2-deleted AIMP2 variant (AIMP2-DX2) gene or a vector comprising the gene, and a method for treating neuronal diseases in animals other than humans, comprising administering the same to a subject in need of treatment. The pharmaceutical composition comprising, as an active ingredient, a AIMP2-DX2 gene or a vector comprising the gene has the effects of apoptosis inhibition, dyskinesia amelioration and oxidative stress inhibition and thus can be widely used for preventing and treating neuronal diseases such as Parkinson's disease and amyotrophic lateral sclerosis.

Abstract: A coffee extraction device is disclosed. A coffee extraction device according to an embodiment of the present invention comprises: a pump which is connected to a water supply source and pressurizes water supplied from the water supply source; a heater for heating the water pressurized by the pump; a coffee extraction unit for extracting coffee using the water heated by the heater; and a discharge member for discharging the coffee, which has been extracted by the coffee extraction unit, to the outside, wherein a vent valve may be provided between the heater and the coffee extraction unit, the vent valve being closed during coffee extraction and being opened after coffee extraction.

Abstract: The present invention relates an apparatus and method for manufacturing an electrode, and more particularly, to an apparatus and method for manufacturing an electrode, which is capable of improving productivity of the electrode in comparison with the related art. According to an aspect of the present invention so at to achieve the above object, a method for manufacturing an electrode includes: a step of preparing a collector; a coating step of applying an electrode active material to one surface or both surfaces of the collector to manufacture an initial electrode; and a first cutting step of cutting the initial electrode coated with the electrode active material to manufacture a plurality of middle-stage electrodes, wherein, in the first cutting step, the initial electrode is cut so that at least one of the plurality of middle-stage electrodes has a length different from those of the other middle-stage electrodes.

Abstract: The present invention relates to a phosphonium-based compound represented by chemical formula 1, an epoxy resin composition containing the same, and a semiconductor device manufactured by using the same.

Abstract: The disclosure provides a system and method for a programmable medical wire that can be preprogrammed, and controlled and reshaped upon command. The system can include a power supply, a controller, and a multilayered wire assembly. The wire assembly includes a core conductor, actuator conductors coupled to the core conductor, selective conductors formed adjacent the core conductor and the actuator conductors, and a protective biocompatible shield around the layers. The selective conductors can be energized to activate the actuator conductors and cause the actuator conductors to bend or twist in a preprogrammed manner. By selectively controlling the direction of movement of the actuator conductors, the wire assembly can be remotely guided through body passageways to the target. Auxiliary equipment such as sensors, micro cameras, detectors, cutters, and other equipment can also be coupled to the wire assembly, and controlled and communicated with through one or more of the selective conductors.

Abstract: A mobile device auxiliary battery is disclosed. The mobile device auxiliary battery can supply electric current to the mobile device. A processing device associated with the auxiliary battery may be wirelessly connected to the mobile device, such as with a Bluetooth interface, and thereby control operational aspects of the battery, including for example control over supplying power to the mobile device. The auxiliary battery may be part of a charging system or kit that includes a uniquely designed separate charger or part of a protective case. In yet another aspect, the protective case may include unitary bumper flexible bumper co-molded to the body of the case and a male connector extending from a nested portion that is adapted to tilt outward from the case to facilitate insertion of the corresponding female port on the mobile device into the connector and into the case.

Abstract: A pharmaceutical composition for preventing and treating liver diseases, includes cromolyn or a pharmaceutically acceptable salt thereof as an active ingredient.

Abstract: A display device has a display surface located at a front surface and an auxiliary sensing surface located at a side surface. The display device includes a display panel including a display area and a non-display area. An input sensing unit is on the display panel and an auxiliary sensing unit is on the auxiliary sensing surface. The auxiliary sensing unit is configured to sense a fingerprint or palm print of a user and is formed in the same layer as any one of the display panel and the input sensing unit.

Abstract: An improved battery case adapted to removably receive, protect and provide power to a mobile device is provided. The case includes a base configured to house a rechargeable battery, a user detachable back face cover capable of providing aesthetic modularity to the consumer and manufacturing advantages, and a bumper that is constructed to include a rigid inner frame or skeleton that includes an outwardly extending rib that is molded on either side with an outer softer and more elastic layer that extends over the face of the mobile device. The bumper can be molded as an integral part of the case or be removably attached to the a component of the case.

Abstract: A sterilization water discharge device is disclosed. A sterilization water discharge device includes: a tray part, which is movably disposed under a discharge member for discharging water and allows sterilization water discharged from the discharge member to be received therein and discharged; and a movement driving part for moving the tray part.

Abstract: A battery cell configured to have a structure in which an electrode assembly, including a positive electrode, a negative electrode, and a separator interposed therebetween, is mounted in a battery case, the electrode assembly including two or more unit cells having different planar sizes, the unit cells being stacked in the height direction on the basis of a plane, at least one first unit cell selected from among the unit cells has an asymmetric structure formed on at least one side of the outer edge thereof on the basis of a middle axis crossing a main body of the first unit cell when viewed from above, and at least one second unit cell selected from among the unit cells has an indented portion indented from at least one side of the second unit cell toward the middle of the second unit cell.

Abstract: An automatic cardiopulmonary resuscitation device and a control method therefor are disclosed. The automatic cardiopulmonary resuscitation device comprises: a movable chest compressor for repeatedly pressing a patient's chest at a preset depth and cycle; a cardiac output measurement unit for measuring a cardiac output of the patient in accordance with the pressurization of the chest compressor; and a processor for changing pressing locations by performing control such that the chest compressor moves according to a preset method, wherein the processor controls the cardiac output measurement unit such that the cardiac output measurement unit measures the patient's cardiac output at each of the changed pressurized locations, selects a pressing location at which the patient's cardiac output becomes the maximum on the basis of the measured cardiac output, and performs control such that the chest compressor moves to the pressing location at which the patient's cardiac output becomes the maximum.

Abstract: A mobile device auxiliary battery is disclosed. The mobile device auxiliary battery can supply electric current to the mobile device. A processing device associated with the auxiliary battery may be wirelessly connected to the mobile device, such as with a Bluetooth interface, and thereby control operational aspects of the battery, including for example control over supplying power to the mobile device. The auxiliary battery may be part of a charging system or kit that includes a uniquely designed separate charger or part of a protective case. In yet another aspect, the protective case may include unitary bumper flexible bumper co-molded to the body of the case and a male connector extending from a nested portion that is adapted to tilt outward from the case to facilitate insertion of the corresponding female port on the mobile device into the connector and into the case.

Abstract: The present invention relates to a novel function of lysyl tRNA synthetase, that is, lysyl tRNA synthetase interacts with 67LR through translocation of KRS into plasma membrane, and so enhances tumor (or cancer) cell migration, thereby having an effect on cancer metastasis. More specifically, it relates to method for controlling cancer metastasis or cancer cell migration by modulating an cellular level of lysyl tRNA synthetase, an use of an expression vector comprising a construct inhibiting KRS expression for preventing or treating cancer, an use of an agent inhibiting KRS activity for preventing or treating cancer, a method for screening an agent which modulates cancer metastasis or cancer cell migration, a method for screening an agent inhibiting an interaction between KRS and 67LR. Accordingly, cancer metastasis and cancer cell migration may be controlled using the inventive KRS, further the cellular metabolism related to laminin receptor (67LR) of plasma membrane may be controlled.

Abstract: This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising benzo-heterocycle derivative or pharmaceutically acceptable salts thereof as an active ingredient. The present inventors confirmed that KRS has an effect on cancer metastasis by facilitating cancer (or tumor) cell migration through interaction with 67LR, and also found that a substance inhibiting the interaction between KRS and 67LR can prevent and treat cancer by inhibiting cancer cell metastasis. Accordingly, the composition of the present invention can inhibit cancer metastasis, and thus provide a novel means for prevention and treatment of cancer.

Abstract: Various examples of methods and systems are provided for increasing productivity of one or more photosynthetic cultures via self-powered light systems. In one example, a system includes a waterproof casing and a light module enclosed within the waterproof casing. The waterproof casing is configured to be neutrally buoyant in a culture tank comprising the one or more photosynthetic cultures. In another example, a method includes placing a self-powered light system within a culture tank, the self-powered light system being neutrally buoyant within the culture tank. The method further includes causing turbulence of water within the culture tank, and the self-powered light system harvests energy to power a light of the self-powered light system via the turbulence of the water within the culture tank.

Abstract: A biological environment simulating apparatus using rotational force includes a mounting unit on which a cell to he pressurized is mounted, a rotational force application unit configured to apply centripetal force to the mounting unit to make the mounting unit perform a circular movement along a circular path about a predetermined center point and a control unit. The control unit controls the rotational force application unit based on a type of the cell and an appropriate pressure condition matched with the type of the cell so that a pressure satisfying the appropriate pressure condition is applied to the cell.

Abstract: The present invention relates an apparatus and method for manufacturing an electrode, and more particularly, to an apparatus and method for manufacturing an electrode, which is capable of improving productivity of the electrode in comparison with the related art. According to an aspect of the present invention so at to achieve the above object, a method for manufacturing an electrode includes: a step of preparing a collector; a coating step of applying an electrode active material to one surface or both surfaces of the collector to manufacture an initial electrode; and a first cutting step of cutting the initial electrode coated with the electrode active material to manufacture a plurality of middle-stage electrodes, wherein, in the first cutting step, the initial electrode is cut so that at least one of the plurality of middle-stage electrodes has a length different from those of the other middle-stage electrodes.

Abstract: An improved battery case adapted to removably receive, protect and provide power to a mobile device is provided. The case includes a base configured to house a rechargeable battery, a user detachable back face cover capable of providing aesthetic modularity to the consumer and manufacturing advantages, and a bumper that is constructed to include a rigid inner frame or skeleton that includes an outwardly extending rib that is molded on either side with an outer softer and more elastic layer that extends over the face of the mobile device. The bumper can be molded as an integral part of the case or be removably attached to the a component of the case.