Abstract: The present invention provides methods for fabricating field-effect devices and sensor arrays. The field of the invention also pertains to methods of using the sensors individually, in combination, and in array fashion to detect molecules. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.

Abstract: Described herein are recombinant integral membrane proteins having multiple transmembrane domains that have been engineered to be less hydrophobic, through alteration of the amino acid sequence of the native protein, but retain the ability to bind their natural ligand. The decreased hydrophobicity of the described proteins makes them more water soluble than the native protein, which allows the described proteins to be expressed in bacteria in large quantities and isolated in the absence of membranes, all while retaining the ability to interact with known ligands.

Abstract: An oral care implement, such as a toothbrush (100), comprises a handle (110) and a head (120). A plurality of tooth cleaning elements (130) may be provided on a front surface (121) of the head (120). The head (120) is formed by a plurality of spaced-apart segments (140-145) made of a rigid material. The segments (140-145) are isolated from one another by channels (157-159B) containing an elastomeric material (146) that flexibly connects the segments (140-145) together. The oral care implement further comprises an elastomeric soft tissue cleaner (200) located on a rear surface (122) of the head (120) opposite the front surface (121) of the head (120). Each of the segments (140-145) comprises a protuberance (163-169) made of the rigid material that extends through the elastomeric soft tissue cleaner (200) and is exposed therethrough.

Abstract: An oral care implement includes a releasable sensory material that invokes a sensory response when in contact with tissues or surfaces of a mouth of a user. In one embodiment, an element is provided that is visually indicative of the sensory response. The oral care implement may also include a soft tissue cleaner provided with the sensory material.

Abstract: An toothbrush having a handle and a head. The handle may include a first component and a second component covering at least a portion of the first component. The first and second components may be chemically compatible. The first and second components may both comprise a hard polyolefin. The first and second components may have different transparencies. In one aspect, the first component may be opaque and the second component may be transparent or semi-transparent. In some aspects, the handle may also include a third component comprising a thermoplastic elastomer. Furthermore, there may be at least one projection extending outwardly from an outer surface of the first component.

Abstract: The present invention provides a UE context release method, eNB and home eNB gateway. The method comprises the following steps: a source eNB determines whether the gateway release determination information sent from the home eNB gateway has been received after a user terminal finishes the handover; and if the source eNB has received the gateway release determination information, the signaling being used to indicate the home eNB gateway to release the context of the user terminal is prohibited from being sent to the home eNB gateway.

Abstract: The present invention discloses a method for access control of a terminal, which is applied to the access control of the terminal in a terminal handover process. The method comprises: a source access network element notifying a target access network element of closed subscriber group configuration information of a source cell via a direct interface, and the target access network element determining whether to allow the terminal to access to a target cell based on closed subscriber group configuration information of the target cell and the closed subscriber group configuration information of the source cell. The present invention further discloses a method for access control of a terminal and an access equipment. The present invention provides a feasible scheme for the access control process when the terminal performs handover via a direct interface.

Abstract: An oral care implement, such as a toothbrush, comprising a flexible head formed of a plurality of flexibly connected segments. In one embodiment, the invention can be an oral care implement comprising a handle and a head. The head can be formed by a plurality of spaced-apart segments constructed of a rigid material and separated by a channel containing an elastomeric material. An elastomeric cleaning element comprising, a base portion and an upper portion extends form a front surface of the head. The elastomeric cleaning element extends from and is connected to the elastomeric material of the channel so that the base portion overlies a portion of each of the front surfaces of the segments on opposing sides of the channel. In another embodiment, the invention can be the elastomeric cleaning element itself, irrespective of the type of head in which it is incorporated. In yet another embodiment, the base portion can be tapered.

Abstract: The disclosure provides a method and a system for implementing a direct interface between access network nodes. The method includes: establishing, by an access network node, a direct interface with a proxy node (300); exchanging, by the access network node, information with an access network node managed by the proxy node through the established direct interface (301). By establishing a direct interface between access network nodes and performing a direct interface flow through a proxy node, the disclosure simplifies the establishment and maintenance of the direct interface on the premise that the handover speed is increased and the signaling load of a core network is decreased, thereby reducing the complexity of the establishment and maintenance of the direct interface.

Abstract: An oral care implement that emits a scent. In one aspect, the invention is directed to a toothbrush comprising: a base component having a gripping region and an oral engaging region, wherein said base component comprises a first scenting agent; and a second component covering at least a portion of said base component in said gripping region, to control a rate of release of said first scenting agent from said base component in said gripping region.

Abstract: An oral care implement, such as a toothbrush. In one aspect, the invention is an oral care implement comprising a handle and a head. A plurality of tooth cleaning elements may extend from a front surface of the head, which is formed by a plurality of spaced-apart segments formed of a rigid material, wherein the plurality of segments include a cruciform segment integrally formed with and extending from a distal end of the handle, a first pair of segments located on opposite sides of a longitudinal portion of the cruciform segment, and a second pair of segments located on opposite sides of the longitudinal portion of the cruciform segment, the first pair of segments located on an opposite side of a transverse portion of the cruciform segment from the second pair of segments. The segments of the first and second pairs are flexibly connected to the cruciform segment.

Abstract: A method and system for accessing a local network by a mobile terminal via a home base station system are provided. The method comprises: a home base station subsystem, in which the mobile terminal is located, sending an ID of a local gateway module in the home base station subsystem to a core network management network element, and the core network management network element determining that the mobile terminal needs to access the local network, and setting up a GPRS tunneling control bearer with the home base station subsystem according to the ID, so that the mobile terminal can access the local network via the home base station subsystem. The method and the system makes the core network acquire the address of the local GGSN/PDN-GW corresponding to the home base station without manual configuration, thus reducing the complexity of the network configuration.

Abstract: The present invention provides a method and device for Access Class (AC) barring. The method comprises: determining the state-related AC barring parameters of a terminal according to the state AC barring information of the terminal and the membership of the terminal in a cell; barring AC according to the determined state-related AC barring parameters. The present invention solves the problem that in related techniques it can not be guaranteed that member UEs own higher priority than non-member UEs do. Hence it improves the effect of AC barring and conduces to improve user experience.