Abstract: Embodiments of this application relate to control parameter optimization technologies. Various embodiments include methods and apparatus for optimizing control parameters. At least one group of initial control parameters within a preset range is randomly generated, to obtain a group of current control parameters; it is determined whether a number of updates has exceeded a preset threshold, referring to a total number of times that the current control parameters have been changed; the group of current control parameters is changed when the number of updates does not reach the preset threshold; and air conditioning control parameters are optimized according to control parameters corresponding to a comprehensive score of a combination when the number of updates reaches the preset threshold.

Abstract: An organic light-emitting diode display device includes a first light-emitting layer, a first anode, a first reflective pattern, and a dielectric material. The first light-emitting layer, the first anode, and the first reflective pattern are located in a first sub-pixel region. The first anode is disposed under the first light-emitting layer in a vertical direction, and the first reflective pattern is disposed under the first anode in the vertical direction. The dielectric material is partly disposed between the first anode and the first reflective pattern, and the first reflective pattern is electrically connected with the first anode.

Abstract: An apparatus for estimating a condition of a battery includes a mode identifying unit configured to identify a usage mode of the battery during a period of time and its corresponding attenuation curve, according to recorded data on battery usage, stored usage modes of the battery and attenuation curves corresponding to the various usage modes, the attenuation curve representing a change of a fully charged capacity of the battery with battery usage; and a condition estimating unit configured to calculate battery degradation according to the recorded data, the identified usage mode and its corresponding attenuation curve, the degradation representing a quantity of the fully charged capacity of the battery that is reduced over the battery usage. The condition of the battery is estimated so as to rationally judge the residual value of the battery in operation.

Abstract: A method for fabricating semiconductor device includes the steps of first forming a gate structure on a substrate, forming a source/drain region adjacent to two sides of the gate structure, forming an epitaxial layer on the source/drain region, forming an interlayer dielectric (ILD) layer on the gate structure, forming a contact hole in the ILD layer to expose the epitaxial layer, forming a low stress metal layer in the contact hole, forming a barrier layer on the low stress metal layer, and forming an anneal process to form a first silicide layer and a second silicide layer.

Abstract: Provided in the present invention is a compound represented by formula (I). The compound has Menin-MLL protein-protein interaction inhibitory activity and cell proliferation inhibitory activity. Also provided in the present invention is a use thereof in the treatment of cancer and other diseases mediated by Menin-MLL interaction.

Abstract: A buck converter with an adaptive turn-on frequency of a pull-up transistor is shown. The buck converter uses a pulse-width modulation (PWM) control signal generator to generate a PWM control signal that drives a power transistor driver to generate PWM signals driving the pull-up transistor and pull-down transistor of the buck converter. Especially, the PWM control signal generator generates the PWM control signal based on feedback of an output voltage of the buck converter as well as feedback of a sensed current about a power transformation component of the buck converter, to modify a turn-on frequency of the pull-up transistor in response to a change in the sensed current.

Abstract: An icemaker includes a casing that receives water from a water supply and is in thermal communication with an evaporator of a sealed system that chills the casing to freeze the water. An auger is mounted within the interior volume and is rotatable to scrape the ice from the casing and urge it through an extruder to form nugget ice. A BLDC motor is mechanically coupled to the auger to selectively rotate the auger. A controller determines a target speed of the auger based at least in part on the ice production parameter, and operates the BLDC motor to rotate the auger at the target speed. The BLDC motor with the speed-closed control loop can provide the constant speed and enough torque to prevent the ice maker from freezing. The controller can adjust the PWM and the voltage will be adjusted slightly, then the torque will be adjusted accordingly.

Abstract: A sensor includes: two friction layers and at least one electrode layer. The two friction layers are respectively made of materials with different electron gain and loss capabilities, and a surface of at least one friction layer includes a multi-level micro-nano structure, so that when there is pressure, equal-quantity and opposite net charges corresponding to the applied pressure are induced on the two friction layers. The multi-level micro-nano structure includes micro-nano columnar structures with at least two different heights. The electrode layer is configured to generate a current based on the net charges. The multi-level structure with different heights is designed.

Abstract: Disclosed is an antibody that specifically recognizes and binds to folate receptor ?, also referred to as anti-folate receptor a antibody or anti-FR? antibody. Also disclosed is an antibody-drug conjugate of the anti-FR? antibody. Disclosed are uses of the anti-FR? antibody and the antibody-drug conjugate in the treatment of diseases related to FR? expression.

Abstract: A lumen stent including a main body stent and a branch stent; the main body stent includes a tubular attachment segment, the attachment segment including a first region and a second region connected to the first region in a circumferential direction; the branch stent is provided in a lumen of the attachment segment and connected to the first region; an axial shortening rate of the first region is smaller than an axial shortening rate of the second region. The lumen stent can reduce the extent to which the branch stent drives the main body stent to shorten.

Abstract: A transient boost controller for controlling a transient boost circuit of a voltage regulator includes a feedback circuit and a processing circuit. The feedback circuit obtains a first feedback signal and a second feedback signal sensed from an output capacitor of the voltage regulator, wherein the first feedback signal is derived from a voltage signal at a first plate of the output capacitor, and the second feedback signal is derived from a voltage signal at a second plate of the output capacitor. The processing circuit generates a detection result according to the first feedback signal and the second feedback signal, and outputs the detection result for controlling the transient boost circuit of the voltage regulator.

Abstract: A bone tissue regeneration product, a method for preparing the bone tissue regeneration product and, and a method for repairing a bone defect. The new use of IGSF10 of the present disclosure can reduce the effective concentration of BMP without obvious adverse reactions, thereby exploring a method to promote bone tissue regeneration and providing new ideas for the treatment of bone defects. The present disclosure is capable of promoting non-bone related cells to produce bones; the method of the present disclosure is also capable of inhibiting the bone loss in inflammatory environments.

Abstract: Recombinant protein of GPER is provided. The recombinant protein has the biological activity of G protein-coupled estrogen receptor.

Abstract: In some embodiments, a computing system extrapolates aggregated interaction data associated with users of an online platform by applying a mixed granularity model to generate extrapolated interaction data for each user in the users. The aggregated interaction data includes a total number of occurrences of a target action performed by the users with respect to the online platform. The extrapolated data includes a series of actions leading to the target action for each user. The computing system identifies an impact of each action in the series of actions for each user on leading to the target action based, at least in part, upon the extrapolating a series of actions associated with the user. User interfaces presented on the online platform can be modified based on at least the identified impacts to improve customization of the user interfaces to the users or enhance an experience of the users.

Abstract: Query processing using online transactional processing (OLTP) and/or online analytical processing (OLAP) use a distributed graph. Optimizations are described including compute pushdown OLTP mode, single thread OLTP mode, and automatic transition between OLTP mode and OLAP mode. A query processing engine comprises an OLTP processing engine, an OLAP processing engine, and a storage (e.g., a computer memory or storage). The OLTP processing engine is configured to process OLTP queries, and the OLAP processing engine is configured to process OLAP queries. The query processing engine may comprise a transition determination engine configured to determine when to transition query processing between OLTP query processing mode and OLAP query processing mode.

Abstract: A method for fabricating semiconductor device includes the steps of first forming a gate structure on a substrate, forming a source/drain region adjacent to two sides of the gate structure, forming an epitaxial layer on the source/drain region, forming an interlayer dielectric (ILD) layer on the gate structure, forming a contact hole in the ILD layer to expose the epitaxial layer, forming a low stress metal layer in the contact hole, forming a barrier layer on the low stress metal layer, and forming an anneal process to form a first silicide layer and a second silicide layer.

Abstract: In some aspects, the techniques described herein relate to a refrigerant compressor, including: a shrouded impeller including a passageway permitting refrigerant to flow from a location radially outside a shroud of the shrouded impeller to a location radially inside the shroud.

Abstract: An apparatus can include a body having a plurality of walls dividing the body into a plurality of sections along a height of the body. A first wall and an opposing second wall can define a section of the plurality of sections. A middle portion of the first wall can be disposed closer to the second wall in a first direction than an end portion of the first wall. The first wall and the second wall can move towards each other in the first direction in response to a force applied on the body in a second direction.

Abstract: The present invention provides a ramp signal generator of a SMPS. The ramp signal generator includes a filter and a charge pump. The filter is configured to filter a PWM signal to generate a filtered PWM signal. The charge pump is configured to receive the PWM signal and the filtered PWM signal to generate an output current, wherein the output current is used to generate a ramp signal, and the ramp signal is used for a PWM signal generator to generate the PWM signal.

Abstract: A buck converter includes a first transistor, a second transistor, an inductor and a capacitor. The first transistor, the second transistor and the inductor are coupled to a switching node. A method includes charging the switching node for a predetermined duration using a first charging current, detecting a voltage at the switching node to obtain a first detection voltage, and determining the connection status of the inductor according to at least the first detection voltage.