Patents by Inventor Jin Zhong Li

Jin Zhong Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LENTIVIRAL VECTORS PSEUDOTYPED WITH A SINDBIS VIRUS ENVELOPE GLYCOPROTEIN
    Publication number: 20160076055
    Abstract: Lentiviral vector particles comprising a Sindbis virus E2 glycoprotein variant and a lentiviral vector genome comprising a sequence of interest are provided. A lentiviral vector particle comprising: (a) an envelope comprising a Sindbis virus E2 glycoprotein variant; and (b) a lentiviral vector genome comprising a sequence of Interest; wherein the E2 glycoprotein variant facilitates infection of dendritic cells by the lentiviral vector particle, and wherein the E2 glycoprotein variant has reduced binding to heparan sulfate compared to a reference sequence (HR strain).
    Type: Application
    Filed: October 1, 2015
    Publication date: March 17, 2016
    Inventors: James M. Allen, Thomas W. Dubensky, Jin Zhong Li, Derek D. Sloan, Neal S. Van Hoeven
  • Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein
    Patent number: 8187872
    Abstract: Lentiviral vector particles comprising a Sindbis virus E2 glycoprotein variant and a lentiviral vector genome comprising a sequence of interest are provided. A lentiviral vector particle comprising: (a) an envelope comprising a Sindbis virus E2 glycoprotein variant; and (b) a lentiviral vector genome comprising a sequence of interest; wherein the E2 glycoprotein variant facilitates infection of dendritic cells by the lentiviral vector particle, and wherein the E2 glycoprotein variant has reduced binding to heparan sulfate compared to a reference sequence (HR strain).
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: May 29, 2012
    Assignee: Immune Design Corp.
    Inventors: James M. Allen, Thomas W. Dubensky, Jr., Jin Zhong Li, Derek D. Sloan, Neal Van Hoeven
  • Lentiviral Vectors Pseudotyped with a Sindbis Virus Envelope Glycoprotein
    Publication number: 20120039932
    Abstract: Lentiviral vector particles comprising a Sindbis virus E2 glycoprotein variant and a lentiviral vector genome comprising a sequence of interest are provided. A lentiviral vector particle comprising: (a) an envelope comprising a Sindbis virus E2 glycoprotein variant; and (b) a lentiviral vector genome comprising a sequence of interest; wherein the E2 glycoprotein variant facilitates infection of dendritic cells by the lentiviral vector particle, and wherein the E2 glycoprotein variant has reduced binding to heparan sulfate compared to a reference sequence (HR strain).
    Type: Application
    Filed: October 20, 2011
    Publication date: February 16, 2012
    Applicant: IMMUNE DESIGN CORP.
    Inventors: James M. Allen, Thomas W. Dubensky, JR., Jin Zhong Li, Derek D. Sloan, Neal S. Van Hoeven
  • LENTIVIRAL VECTORS PSEUDOTYPED WITH A SINDBIS VIRUS ENVELOPE GLYCOPROTEIN
    Publication number: 20110064763
    Abstract: Lentiviral vector particles comprising a Sindbis virus E2 glycoprotein variant and a lentiviral vector genome comprising a sequence of interest are provided. A lentiviral vector particle comprising: (a) an envelope comprising a Sindbis virus E2 glycoprotein variant; and (b) a lentiviral vector genome comprising a sequence of interest; wherein the E2 glycoprotein variant facilitates infection of dendritic cells by the lentiviral vector particle, and wherein the E2 glycoprotein variant has reduced binding to heparan sulfate compared to a reference sequence (HR strain).
    Type: Application
    Filed: July 23, 2010
    Publication date: March 17, 2011
    Applicant: IMMUNE DESIGN CORP.
    Inventors: James M. Allen, Thomas W. Dubensky, JR., Jin Zhong Li, Derek D. Sloan, Neal S. Van Hoeven