Abstract: The present invention belongs to the medical field, and relates to novel ?-lactamase inhibitors, for the treatment of bacterial infections in combination with ?-lactam antibiotics, including infection caused by drug resistant organisms and especially multi-drug resistant organisms. The present invention includes compounds according to formula (I): or pharmaceutically acceptable salts thereof, wherein M and R are as defined herein.

Abstract: A method for forming a test flume usable in hydraulic engineering and debris-flow hazard mitigation is provided. The test flume has a foundation flume and an expansion flume. The expansion flume has a lower edge connected to an upper edge of the foundation flume. A hydraulic radius of the test flume is determined based on a model test. A width of the foundation flume is selected based on a size of the test site of the model test. A coefficient is obtained and a width of the test flume is obtained. A cross section curve equation of the expansion flume is obtained based on the hydraulic radius of the test flume, the coefficient, the width of the test flume and the width of the foundation flume. The test flume is formed based on the cross section curve equation of the expansion flume.

Abstract: The method for preventing and controlling glacial lake outbreak flood and related debris flows by the present invention is mainly controlling the scale of the floods by separating water and rocks and dispersing its energy step by step. The cascading amplification effects of floods can be reduced by controlling the initiation of source material with energy dissipation by using ground sills, groups of piles, and placed large stones and prefabricated artificial structures. The diversion dam built in the downstream area discharge floods in different layers, which can quickly guide water to the main river. The preconstructed engineering system can be used in a timely manner to prevent and control floods and debris flows induced by a sudden outburst of glacial lakes in areas with important facilities and inhabitants enduring the risk of natural hazards. Prevention and control systems can separate floods and debris flows and dissipate their energy.

Abstract: A method for forming a test flume usable in hydraulic engineering and debris-flow hazard mitigation is provided. The test flume has a foundation flume and an expansion flume. The expansion flume has a lower edge connected to an upper edge of the foundation flume. A hydraulic radius of the test flume is determined based on a model test. A width of the foundation flume is selected based on a size of the test site of the model test. A coefficient is obtained and a width of the test flume is obtained. A cross section curve equation of the expansion flume is obtained based on the hydraulic radius of the test flume, the coefficient, the width of the test flume and the width of the foundation flume. The test flume is formed based on the cross section curve equation of the expansion flume.

Abstract: A gate driving circuit includes 4n stages of shift register units, and n stages of inversion units. One of the inversion units is disposed between every two groups of four adjacent stages of shift register units. A (n+1)th stage of the inversion units is disposed between two of the shift register units, and configured to output in inverted phases gate driving signals outputted by the two shift register units in a heavy-load screen stage, and output in positive phases gate driving signals outputted by the two shift register units in a normal screen stage.

Abstract: A gate driving circuit includes 4n stages of shift register units, and n stages of inversion units. One of the inversion units is disposed between every two groups of four adjacent stages of shift register units. A (n+1)th stage of the inversion units is disposed between two of the shift register units, and configured to output in inverted phases gate driving signals outputted by the two shift register units in a heavy-load screen stage, and output in positive phases gate driving signals outputted by the two shift register units in a normal screen stage.