Abstract: The present invention belongs to the medical field, and relates to novel ?-lactamase inhibitors, for the treatment of bacterial infections in combination with ?-lactam antibiotics, including infection caused by drug resistant organisms and especially multi-drug resistant organisms. The present invention includes compounds according to formula (I): or pharmaceutically acceptable salts thereof, wherein M and R are as defined herein.

Abstract: A device and method for preparing a thermosetting bonded magnet are provided, the device includes a compressed air glue feeding tank and a composite-function mold. A feeding end of the compressed air glue feeding tank is connected to the composite-function mold. The composite-function mold includes a housing, the housing is disposed at an upper end and a lower end of the composite-function mold, and the housing includes a polytetrafluoroethylene upper cover and a polytetrafluoroethylene lower cover; the polytetrafluoroethylene upper cover and the polytetrafluoroethylene lower cover are respectively disposed at the upper end and the lower end of composite-function mold. The method uses a silica gel material as a binder for anisotropic magnets, and the selected raw materials and process are suitable for quickly obtaining a uniform magnet slurry. The curing process is controllable, and there is no organic solvent or heating during the mixing process.

Abstract: Disclosed are a display apparatus and a display method. The display apparatus includes a display; a remote controller, including multiple keys and configured to: output an infrared signal carrying a first infrared key value in response to selection of an integrated key from the user, the integrated key is configured for replacing at least two omitted keys not disposed on the remote controller, the omitted keys are keys not arranged on the remote controller; and a controller is configured to: identify an infrared key value of an infrared signal corresponding to the integrated key; control the display to display a key interface when the infrared key value being the first infrared key value; the key interface includes at least two first controls corresponding to the omitted keys; and generate a target infrared key value when a selection of one of the at least two first controls from the user.

Abstract: A device and method for preparing a thermosetting bonded magnet are provided, the device includes a compressed air glue feeding tank and a composite-function mold. A feeding end of the compressed air glue feeding tank is connected to the composite-function mold. The composite-function mold includes a housing, the housing is disposed at an upper end and a lower end of the composite-function mold, and the housing includes a polytetrafluoroethylene upper cover and a polytetrafluoroethylene lower cover; the polytetrafluoroethylene upper cover and the polytetrafluoroethylene lower cover are respectively disposed at the upper end and the lower end of composite-function mold. The method uses a silica gel material as a binder for anisotropic magnets, and the selected raw materials and process are suitable for quickly obtaining a uniform magnet slurry. The curing process is controllable, and there is no organic solvent or heating during the mixing process.

Abstract: A flexible permanent magnetic material, a preparation method and an application thereof in magnetic biological effect products are provides, relating to the technical field of medical equipment. Raw materials of the flexible permanent magnetic material of the application include the following components in parts by weight: 0-70 parts of anisotropic neodymium iron boron powder and 0-40 parts of anisotropic samarium iron nitrogen powder and 3-20 parts of binder.

Abstract: The present invention relates to a compound, and in particular to a bromophenol-pyrazoline compound and a synthesis method and use thereof. The bromophenol-pyrazoline compound is represented by a general structural formula below: The bromophenol-pyrazoline compound provided in the present invention has efficient inhibitory activity against the main protease Mpro, and interferes with the replication of coronavirus in cells, indicating that the compound has the effect of treating coronavirus pneumonia and thus has a broad prospect of application in the preparation of drugs for treating coronavirus pneumonia.

Abstract: The invention belongs to the technical field of medicine, and particularly relates to use of bromophenol-pyrazoline compounds in the treatment of porcine coronavirus diseases. Through the research in the invention, it is found that the bromophenol-pyrazoline compounds inhibit replication of porcine coronaviruses at a cellular level, and can treat porcine coronavirus diseases (such as PEDV and TGEV) in clinical trials, greatly improving the survival rate of infected piglets, so the compounds can be used to prepare drugs for treating porcine coronavirus diseases.

Abstract: The disclosure discloses an apparatus for online volumetrically detecting grain yield based on weight calibration comprising left volumetric granary, right volumetric granary and push board. The left volumetric granary is provided on its bottom with first weighing sensor, and in its side with unload grain port opening and first closing door, the right volumetric granary is provided on its bottom with second weighing sensor, and in its side with unload grain port opening and second closing door, the left volumetric granary and the right volumetric granary are provided on their tops with the push board, the push board is a hollow box structure with a top side and a bottom side both opened, and is slidably mounted to a top of the left volumetric granary and the right volumetric granary through a slide driving mechanism.

Abstract: The present disclosure relates to the technical field of microwave absorption, and in particular, to a multi-layer wave absorber structure and use thereof. The multi-layer wave absorber structure has a sandwich structure, and an intermediate layer of the sandwich structure is an electromagnetic loss-free dielectric layer. The electromagnetic loss-free dielectric layer includes a vacuum layer, an air layer, a paraffin layer, or a polytetrafluoroethylene layer. The added electromagnetic loss-free dielectric layer enhances impedance matching by modulating phases of electromagnetic waves, such that loss of the electromagnetic waves in a composite wave absorbing layer of the multi-layer wave absorber structure is enhanced, and an effective absorption bandwidth is further improved.

Abstract: An application of a glucan in the preparation of a drug. A ?-1,3/1,6-glucan is used for preparing a pharmaceutical composition or formulation. The pharmaceutical composition or formulation can enhance the antitumor effect of immunotherapy, radiotherapy, or chemotherapy, and is used for treating leukopenia and/or thrombocytopenia.

Abstract: The present disclosure discloses the use of Tegaserod or a pharmaceutically acceptable salt thereof as a JAK-STAT3 signaling pathway inhibitor and an immunomodulator in the preparation of an anti-tumor drug. Tegaserod and the pharmaceutically acceptable salt thereof show a very excellent inhibitory effect on the growth of various tumor cells in vivo and in vitro, and are expected to be used in the treatment of various cancers.

Abstract: The invention belongs to the technical field of medicine, and particularly relates to use of bromophenol-pyrazoline compounds in the treatment of porcine coronavirus diseases. Through the research in the invention, it is found that the bromophenol-pyrazoline compounds inhibit replication of porcine coronaviruses at a cellular level, and can treat porcine coronavirus diseases (such as PEDV and TGEV) in clinical trials, greatly improving the survival rate of infected piglets, so the compounds can be used to prepare drugs for treating porcine coronavirus diseases.

Abstract: The invention discloses a manufacturing process of a display screen cover, and a display screen. The manufacturing process includes the following steps: S1, providing a lamp panel provided with LED lamp beads; S2, arranging a glue barrier; S3, filling the hollow region of the glue barrier with glue I, and covering the LED lamp beads with the glue I; S4, providing a press plate; S5, curing the glue I; and S6, removing the press plate and the glue barrier. The cover does not need to be additionally assembled on the lamp panel, so that the lamp beads are protected against damage from the cover, and the yield of display screens is increased; and gaps between the lamp beads are completely filled with the cover, so that the lamp beads are fully protected.

Abstract: The present invention relates to a compound, and in particular to a bromophenol-pyrazoline compound and a synthesis method and use thereof. The bromophenol-pyrazoline compound is represented by a general structural formula below: The bromophenol-pyrazoline compound provided in the present invention has efficient inhibitory activity against the main protease Mpro, and interferes with the replication of coronavirus in cells, indicating that the compound has the effect of treating coronavirus pneumonia and thus has a broad prospect of application in the preparation of drugs for treating coronavirus pneumonia.

Abstract: The present invention discloses a fresh air assembly and an air conditioner. Fresh air is introduced to one side of evaporators, flows into a wind chamber from the evaporators, and finally is discharged to the indoor. The fresh air undergoes dehumidification, cooling, or heating processing performed by the evaporators, and therefore functions of the evaporators are fully utilized. A dehumidifier module is removed, which reduces noise, decreases overall energy consumption and costs, and makes cleaning and maintenance more convenient.

Abstract: The disclosure discloses an apparatus for online volumetrically detecting grain yield based on weight calibration comprising left volumetric granary, right volumetric granary and push board. The left volumetric granary is provided on its bottom with first weighing sensor, and in its side with unload grain port opening and first closing door, the right volumetric granary is provided on its bottom with second weighing sensor, and in its side with unload grain port opening and second closing door, the left volumetric granary and the right volumetric granary are provided on their tops with the push board, the push board is a hollow box structure with a top side and a bottom side both opened, and is slidably mounted to a top of the left volumetric granary and the right volumetric granary through a slide driving mechanism.

Abstract: The invention discloses a manufacturing process of a display screen cover, and a display screen. The manufacturing process includes the following steps: S1, providing a lamp panel provided with LED lamp beads; S2, arranging a glue barrier; S3, filling the hollow region of the glue barrier with glue I, and covering the LED lamp beads with the glue I; S4, providing a press plate; S5, curing the glue I; and S6, removing the press plate and the glue barrier. The cover does not need to be additionally assembled on the lamp panel, so that the lamp beads are protected against damage from the cover, and the yield of display screens is increased; and gaps between the lamp beads are completely filled with the cover, so that the lamp beads are fully protected.

Abstract: This invention relates to a method for preparing a star-shaped polycarboxylate superplasticizer by the first esterification step with polyol and (meth)acrylic acid as main reactants and the second polymerization step. In the first step, the star-shaped polymerizable active ends were synthesized by esterification between polyol and (meth)acrylic acid in the presence of catalyst. In the second step, the final star-shaped polycarboxylate superplasticizer was prepared by radical polymerization among the product obtained in first step, unsaturated polyoxyethylene ethers, molecular weight regulator and unsaturated carboxylic acid in the presence of initiator. The production process of this invention exhibits some characteristics including simple, easily controllable, high polymerization degree, low cost and pollution free. The star-shaped molecular structure of polycarboxylate superplasticizer can be achieved through synthesizing active “core” by esterification and “arm” by radical polymerization.

Abstract: This invention relates to a method for preparing a star-shaped polycarboxylate superplasticizer by the first esterification step with polyol and (meth)acrylic acid as main reactants and the second polymerization step. In the first step, the star-shaped polymerizable active ends were synthesized by esterification between polyol and (meth)acrylic acid in the presence of catalyst. In the second step, the final star-shaped polycarboxylate superplasticizer was prepared by radical polymerization among the product obtained in first step, unsaturated polyoxyethylene ethers, molecular weight regulator and unsaturated carboxylic acid in the presence of initiator. The production process of this invention exhibits some characteristics including simple, easily controllable, high polymerization degree, low cost and pollution free. The star-shaped molecular structure of polycarboxylate superplasticizer can be achieved through synthesizing active “core” by esterification and “arm” by radical polymerization.

Abstract: New methods of forming color-coated gemstones are provided. These methods broadly comprise subjecting a source of metal (e.g., an organometallic compound) to a vapor deposition process so as to form the metal source into a vapor that is subsequently deposited onto the surface of a previously heated gemstone. The vapor is also diffused into the gemstone so as to form a mixed zone of gemstone having the metal source dispersed or intermixed therein. The coated gemstone is then subjected to heat treatment to alter the valence state of the metal in the coating until the desired colored coating is obtained, resulting in coatings having superior adhesion and optical properties.