Abstract: The invention relates to compounds of formula (I) with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers.

Abstract: An X-ray tube and an X-ray imaging device are disclosed. The X-ray tube comprises: a glass envelope; a cathode assembly, accommodated inside the glass envelope; and a core column structure, connected to the glass envelope and the cathode assembly, such that the cathode assembly is sealed inside the glass envelope. The core column structure comprises: a metal flat plate, wherein the cathode assembly is fixed to the metal flat plate; and a sealing bead, wherein the sealing bead is arranged in the metal flat plate, and an electrically conductive support rod connected to the cathode assembly passes through two ends of the sealing bead. The X-ray tube enables generated heat to be rapidly transferred to a cooling medium via thermally conductive metal to improve heat dissipation efficiency.

Abstract: An X-ray tube and an X-ray imaging device are disclosed. The X-ray tube comprises: a glass envelope; a cathode assembly, accommodated inside the glass envelope; and a core column structure, connected to the glass envelope and the cathode assembly, such that the cathode assembly is sealed inside the glass envelope. The core column structure comprises: a metal flat plate, wherein the cathode assembly is fixed to the metal flat plate; and a sealing bead, wherein the sealing bead is arranged in the metal flat plate, and an electrically conductive support rod connected to the cathode assembly passes through two ends of the sealing bead. The X-ray tube enables generated heat to be rapidly transferred to a cooling medium via thermally conductive metal to improve heat dissipation efficiency.

Abstract: An exchange membrane containing modified maleimide oligomers comprising sulfonated poly(aryl ether ketone) (S-PAEK) and modified maleimide oligomers. The exchange membrane uses the modified maleimide oligomers having a hyper-branched architecture as matrix, and introduces them into S-PAEK to constitute semi-interpenetration network (semi-IPN), so as to intensify water holding capacity, chemical resistance, the electrochemical stability and thermal resistance of the ionic/proton exchange membrane. The exchange membrane can be used to fabricate the membrane electrode assemblies, fuel cells, and be applied them to the fields of seawater desalination, heavy water and sewage treatment, and biomass-energy resources.