Abstract: The present disclosure provides a kit and method for constructing a long-acting depression animal model. The present disclosure adopts Bacille Calmette-Guerin (BCG) (or Mycobacterium bovis (M bovis)) and low-dose pertussis toxin (PTX) for combined induction, which greatly reduces modeling cost. A mouse model constructed by the method of the present disclosure can clearly distinguish a time interval of pathological behaviors from a time interval of depression-like behaviors and has prominent face validity and predictive validity. The method of the present disclosure is simple and convenient and does not require a large number of tedious daily operations as the depression model construction by chronic unpredictable stress, chronic restraint stress, social defeat, mother-child separation, or the like. The mouse model of the present disclosure can provide a valuable long-term intervention window for research on antidepressant therapy.

Abstract: A cache memory device is provided in the disclosure. The cache memory device includes a first AGC, a compression circuit, a second AGC, a virtual tag array, and a comparator circuit. The first AGC generates a virtual address based on a load instruction. The compression circuit obtains the higher part of the virtual address and generates a target hash value based on the higher part of the virtual address. The second AGC generates the lower part of the virtual address based on the load instruction. The virtual tag array obtains the lower part and selects a set of memory units. The comparator circuit compares the target hash value to a hash value stored in each memory unit of the set of memory units. When the comparator circuit generates the virtual tag miss signal, the comparator circuit transmits the virtual tag miss signal to the reservation station.

Abstract: A starch biosynthesis method may implement total artificial biosynthesis from simple compounds such as dihydroxyacetone, formaldehyde, formic acid and methanol to starch. By coupling with methods such as chemical reduction of carbon dioxide, even total artificial biosynthesis of starch taking carbon dioxide as a starting raw material can be implemented. The method can utilize carbon dioxide of high concentration and high density and electric energy and hydrogen energy of high energy density, is more suitable for an industrial production mode, and the production cycle is shortened from several months in farming to several days.

Abstract: A cache memory device is provided in the disclosure. The cache memory device includes a first AGC, a compression circuit, a second AGC, a virtual tag array, and a comparator circuit. The first AGC generates a virtual address based on a load instruction. The compression circuit obtains the higher part of the virtual address and generates a target hash value based on the higher part of the virtual address. The second AGC generates the lower part of the virtual address based on the load instruction. The virtual tag array obtains the lower part and selects a set of memory units. The comparator circuit compares the target hash value to a hash value stored in each memory unit of the set of memory units. When the comparator circuit generates the virtual tag miss signal, the comparator circuit transmits the virtual tag miss signal to the reservation station.

Abstract: The subject application relates to a method for treating retinitis pigmentosa, comprising the step of: enabling a subject in need thereof to have a functional RHO gene, wherein the functional RHO gene does not comprise a mutation site selected from the group consisting of c.C50T and c.C403T. The subject application also relates to a method for editing the RHO gene, and a composition for treating retinitis pigmentosa in a subject.

Abstract: The present invention is directed to resist and etching residue removing compositions containing at least one nucleophilic amine compound possessing reduction and oxidation potentials, a two-carbon atom linkage alkanolamine compound, and optionally water and/or one or more corrosion inhibitors. The compositions may be substantially free of hydroxylamine, polar organic solvents, water, corrosion inhibitors, or a combination thereof. The compositions are useful in processes for removing resists and etching residue from metal or metal alloy substrates or substrate layers used in micro-circuitry fabrication.

Abstract: The present invention is directed to resist and etching residue removing compositions containing at least one nucleophilic amine compound possessing reduction and oxidation potentials, a two-carbon atom linkage alkanolamine compound, and optionally water and/or one or more corrosion inhibitors. The compositions may be substantially free of hydroxylamine, polar organic solvents, water, corrosion inhibitors, or a combination thereof. The compositions are useful in processes for removing resists and etching residue from metal or metal alloy substrates or substrate layers used in micro-circuitry fabrication.