Patents by Inventor Jing-Ren Zhang
Jing-Ren Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10960066Abstract: Provided is a method of treating or preventing pneumococcal disease. Also provided is a method of diagnosing pneumococcal disease.Type: GrantFiled: August 16, 2019Date of Patent: March 30, 2021Assignee: TSINGHUA UNIVERSITYInventors: Jing-Ren Zhang, Yang Wang, Zhensong Wen
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Publication number: 20190365880Abstract: Provided is a method of treating or preventing pneumococcal disease. Also provided is a method of diagnosing pneumococcal disease.Type: ApplicationFiled: August 16, 2019Publication date: December 5, 2019Inventors: Jing-Ren ZHANG, Yang WANG, Zhensong WEN
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Publication number: 20160266112Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: December 14, 2015Publication date: September 15, 2016Inventors: Steven J. NORRIS, Jing-Ren ZHANG, John M. HARDHAM, Jerrilyn K. HOWELL, Alan G. BARBOUR, George M. WEINSTOCK
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Patent number: 9212218Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: January 10, 2013Date of Patent: December 15, 2015Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 8354240Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: December 5, 2011Date of Patent: January 15, 2013Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jemlyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20120122238Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: December 5, 2011Publication date: May 17, 2012Inventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jemlyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 8071109Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: August 9, 2010Date of Patent: December 6, 2011Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20100317026Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: August 9, 2010Publication date: December 16, 2010Inventors: STEVEN J. NORRIS, JING-REN ZHANG, JOHN M. HARDHAM, JERRILYN K. HOWELL, ALAN G. BARBOUR, GEORGE M. WEINSTOCK
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Patent number: 7785597Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: August 7, 2006Date of Patent: August 31, 2010Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20070117970Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: August 7, 2006Publication date: May 24, 2007Inventors: Steven Norris, Jing-Ren Zhang, John Hardham, Jerrilyn Howell, Alan Barbour, George Weinstock
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Patent number: 7135176Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: May 24, 2004Date of Patent: November 14, 2006Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 6878816Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: August 16, 2002Date of Patent: April 12, 2005Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20040214225Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: May 24, 2004Publication date: October 28, 2004Inventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 6740744Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: July 31, 2002Date of Patent: May 25, 2004Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 6719983Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: August 16, 2002Date of Patent: April 13, 2004Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20040044192Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: August 16, 2002Publication date: March 4, 2004Applicant: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20030092903Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: July 31, 2002Publication date: May 15, 2003Applicant: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Publication number: 20030060618Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: ApplicationFiled: August 16, 2002Publication date: March 27, 2003Applicant: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock
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Patent number: 6437116Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the deletion of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.Type: GrantFiled: January 27, 1999Date of Patent: August 20, 2002Assignee: Board of Regents, The University of Texas SystemInventors: Steven J. Norris, Jing-Ren Zhang, John M. Hardham, Jerrilyn K. Howell, Alan G. Barbour, George M. Weinstock