Patents by Inventor Jing-Shan Yang

Jing-Shan Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of culturing and modulating the growth of hair follicular stem cells
    Patent number: 5556783
    Abstract: A method of culturing hair follicular stem cells by isolating a subpopulation of follicular keratinocytes from the upper portion of a hair follicle, dispersing the isolated keratinocytes into a single cell suspension, and growing the dispersed isolated keratinocytes in the presence of 3T3 feeder cells is provided. A method of evaluating the efficacy of agents for modulating the activity of bulge cell populations by exposing bulge cells to an agent to be tested and comparing the response of the test cells to established controls for bulge cells is also provided. Methods of modulating the activity of hair follicular stem cells by identifying a subpopulation of follicular keratinocytes from the upper portion of a hair follicle and contracting the cells with a selected agent to stimulate growth or to selectively kill the cells is also provided.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: September 17, 1996
    Assignees: Trustees of Univ. of Penna, New York Univ.
    Inventors: Robert M. Lavker, Tung-Tien Sun, Jing-Shan Yang