Abstract: A compound containing a bis(azanylylidene) sulfonyl structure of formula (I) as a PKR agonist and/or USP9X inhibitor, which can be used for treating related diseases mediated and regulated by PKR and USP9X, wherein the related diseases comprise, but are not limited to: sickle-cell anemia, ?-thalassemia, hereditary non-spherocytic hemolytic anemia, hemolytic anemia, hereditary spherocytosis, hereditary elliptocytosis, abetalipoproteinemia, paroxysmal nocturnal hemoglobinuria, acquired hemolytic anemia, congenital anemia, anemia of chronic diseases, colorectal cancer, kidney cancer, pancreatic cancer, breast cancer, lung cancer, esophageal cancer, melanoma, lymphoma, glioblastoma, or multiple myeloma.

Abstract: A communication device includes an NTN communication unit configured to connect to a non-terrestrial network, a sensor unit, and a control unit. The control unit is configured to: acquire, via the sensor unit, presence information regarding a range of presence of an obstruction in space including an outgoing or incoming direction of radio waves during communication via the NTN communication unit; and performs a process based on a line of sight in which the radio waves are transmittable and receivable between the NTN communication unit and the non-terrestrial network in the space, the line of sight being estimated from the acquired presence information.

Abstract: A processing device for film cooling holes on blade of aviation engine includes a working box. A workpiece clamping mechanism is arranged in the working box for holding the workpiece. A cover body having an internal space communicated with an internal space of the working box is connected to an upper part of the working box. A laser processing mechanism is connected to a top end of the cover body and can produce laser rays to carry out laser processing on the workpiece. The cover body is connected to a liquid supply mechanism and an acid gas filtration mechanism. The liquid supply mechanism can spray an acidic solution to the workpiece in the working box, and the working box can collect the acidic solution. The acid gas filtration mechanism can filter acid steam produced during processing. A working method of the processing device is also provided.

Abstract: A communication system configured to provide a communication network to a communication device includes a control device. The control device is configured to execute: a reception process of receiving, from an organization outside the communication system, threat information regarding a threat to the communication device that uses the communication network; and a protection process of protecting the communication device based on the received threat information.

Abstract: Disclosed herein are novel selectable markers and uses thereof. Specifically, provided herein are uses of nucleotide sequences encoding a glutamine synthetase (GS) derived from platypus, turtle, rat, opossum, wombat, or zebra finch as selectable markers for identifying genomic loci with high transcriptional activity or host cells having high productivity of a protein of interest, and/or allowing accelerated cell isolation expressing a protein of interest. Related methods of screening, methods of production, and expression systems are also included.

Abstract: Provided are a fatigue-resistant supramolecular polyurethane (PU), and a preparation method and use thereof. The preparation method includes: mixing a diol, a diisocyanate, a catalyst, and a first organic solvent to obtain a mixture, and subjecting the mixture to prepolymerization to obtain a PU prepolymer, the diol being selected from the group consisting of a polyester diol and a polyether diol; mixing the PU prepolymer, 4,4?-diaminodicyclohexylmethane, and a second organic solvent to obtain a mixed mixture, and subjecting the mixed mixture to chain extension to obtain a chain extension product; and mixing the chain extension product, reinforcing phase total organic carbon (TOC), and a third organic solvent to obtain a mixed system, and subjecting the mixed system to first addition reaction to obtain the fatigue-resistant supramolecular PU, the reinforcing phase TOC having a structure shown in formula I.

Abstract: The present disclosure provide a display device including a light source, a light transmitting layer including a plurality of micro-lens structures, and a light splitting layer including at least one liquid crystal grating layer and a prism layer. At a first period, light exiting from the first prism surface formed by transmitting a part of the parallel light through the liquid crystal grating layer has a first exit angle. At another period, light exiting from the first prism surface formed by transmitting another part of the parallel light has a second exit angle. A first image is formed in a direction of the first exit angle at a first period, a second image is formed in a direction of the second exit angle at a second period, and the first image and the second image are spliced to form a stereoscopic display image under a larger viewing angle.

Abstract: The present disclosure provides a signal transmission method and a signal transmission device. The signal transmission method includes: transmitting a first reference signal, the first reference signal indicating that the first network device is subjected to remote interference; and receiving a second reference signal, the second reference signal indicating that there is the remote interference and/or atmospheric ducting phenomenon.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes a panel body and a light-splitting component; the light-splitting component is disposed on a light-emitting side of the panel body; the light-splitting component includes a plurality of light-splitting members arranged along a first direction, and each of the light-splitting members includes a first side edge and a second side edge opposite to each other along the first direction; for any two adjacent light-splitting members, a distance between the first side edge of one of the light-splitting members and the first side edge of another one of the light-splitting members along the first direction is defined as a preset distance, X, which satisfies the following equation: X??Y, in which ? indicates angular resolution of human eye, and Y indicates an optimal viewing distance for the human eye.

Abstract: Provided are novel selectable markers and uses thereof. Specifically, provided are uses of nucleotide sequences encoding a glutamine synthetase (GS) derived from Alligator, green anole, or spotted gar as selectable markers for identifying genomic loci with high transcriptional activity or host cells having high productivity of a protein of interest, and/or for accelerating the identification process. Related methods of screening, methods of production, and expression systems are also included.

Abstract: A light-emitting component includes a light-emitting unit and an electrically insulating layer. The light-emitting unit includes a first semiconductor layer, an active layer, and a second semiconductor layer, which are stacked on one another along a stacking direction in such order. The second semiconductor has a lower surface distal from the active layer. The electrically insulating layer is disposed to cover a first portion and to expose a second portion of the lower surface of the second semiconductor layer. A fluorine-containing region is formed in the second semiconductor layer. Methods for making the light-emitting component are also disclosed.

Abstract: Provided are anti-TNFR2 (tumor necrosis factor receptor 2) antibodies, antigen-binding fragments, and the uses thereof.

Abstract: Each of a plurality of information processing apparatuses mounted on different mobile bodies performs machine learning using local data, and generates a local model. Each of the plurality of information processing apparatuses exchanges an evaluation value with another information processing apparatus mounted on each of the other mobile bodies by proximity communication. Then, among the information processing apparatuses whose evaluation value is equal to or greater than a predetermined value, the number of information processing apparatuses whose upper limit is the first threshold value transmits local model information indicating the generated local model to the server device.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes a substrate and a pixel electrode layer disposed on the substrate. The pixel electrode layer includes pixel electrode groups arranged in an array in the first direction and second direction. Each pixel electrode group includes a first sub-pixel electrode and a third sub-pixel electrode arranged in the third direction, and a second sub-pixel electrode and a fourth sub-pixel electrode arranged in the fourth direction. The first and third sub-pixel electrodes are respectively located on two sides of an imagined connecting line connecting the geometric centers of the second sub-pixel electrode and the fourth sub-pixel electrode. Projections of the second sub-pixel electrode and the first sub-pixel electrode along the first direction at least partially overlap. Projections of the fourth sub-pixel electrode and the third sub-pixel electrode in the first direction at least partially overlap.

Abstract: The present application relates to a pixel arrangement structure, including first sub-pixels, second sub-pixels, third sub-pixels, and fourth sub-pixels. Centers of two of the first sub-pixels arranged opposite to each other and centers of two of the second sub-pixels arranged opposite to each other are taken as vertices and are connected to form a virtual quadrilateral. The virtual quadrilateral includes two equal sides arranged opposite to each other, a short side and a long side arranged opposite to each other and connected to vertices of the equal sides. The short side of the virtual quadrilateral is not parallel to the long side of the virtual quadrilateral. One of the third sub-pixels or one of the fourth sub-pixels is arranged in the virtual quadrilateral, and the third sub-pixel and the fourth sub-pixel emits light in a same color.

Abstract: The present application relates to a pixel arrangement structure, comprising a plurality of first pixel units and a plurality of second pixel units. The plurality of first pixel units and the plurality of second pixel units are alternately arranged in a first direction and a second direction. The first pixel units and the second pixel units respectively comprises a first sub-pixel, a second sub-pixel, a third sub-pixel, and a fourth sub-pixel. The first sub-pixel is located at one side of an imaginary connecting line between a center of the third sub-pixel and a center of the fourth sub-pixel, and the second sub-pixel is located at another side of the imaginary connecting line between the center of the third sub-pixel and the center of the fourth sub-pixel. After the second pixel units are rotated by a predetermined angle, sub-pixel arrangement structures thereof are mirror-symmetrical to that of the first pixel units.