Patents by Inventor Jing Xiong

Jing Xiong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11165064
    Abstract: Systems, methods, and compositions are disclosed for a Li-substituted layered-tunneled O3/spinel Na(NixFeyMnz)O2 cathode material, Na0.87Li0.25Ni0.4Fe0.2Mn0.4O2+? (LS-NFM) for enhanced sodium ion storage and cycling stability. The LS-NFM electrode is prepared by adjusting the stoichiometric ratio of the Na ion over the sum of Li and transition metal ions below 1. The Rietveld refinement of XRD data indicates that the cathode is composed of 94% layered and 6% spinel components. When cycled at a high current density of 100 mA g?1, LS-NFM cathode exhibited a first-cycle Coulombic efficiency of 88% and reversible discharge capacity of 107 mAh g?1 after 50 cycles with the capacity retention of 95%.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: November 2, 2021
    Assignee: Boise State University
    Inventors: Hui Xiong, Changjian Deng, Jing Xu
  • Patent number: 11152500
    Abstract: The application discloses a tunneling field-effect transistor, including: a substrate layer; a rectangular semiconductor strip formed on an upper surface of the substrate layer, where the rectangular semiconductor strip includes a first source region, a first channel region, a drain region, a second channel region, and a second source region that are disposed in sequence along a first direction; a first gate dielectric layer covering an outer surface of a first part of the first source region and a second gate dielectric layer covering an outer surface of a third part of the second source region.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: October 19, 2021
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jing Zhao, Chen-Xiong Zhang
  • Patent number: 11142132
    Abstract: A vehicle rack includes a cargo shelf, the cargo shelf including two beams and two fixing rods; four supporting frames, each beam being provided with two supporting frames that are movable along the beam, the two fixing rods being secured between two corresponding supporting frames on the two beams, a U-shaped plug interface being formed at the top of each supporting frame; a mobile frame that is movable along the beams and is U-shaped, the mobile frame including a horizontal rod and two vertical rods, a U-shaped plug interface I being formed at the top of each vertical rod; six connectors, each connector being provided with a clamping interface that opens through at bottom of the connector so that the connector can clamp the beam from top and then be inserted into the U-shaped plug interface or the U-shaped plug interface I; and six bolts.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: October 12, 2021
    Assignee: FORCOME (ZHEJIANG) CO., LTD.
    Inventors: Xiaojun Ni, Chengsheng Fang, Jing Xiong, Jiancheng Wang
  • Patent number: 11142534
    Abstract: The present invention relates to a process for synthesizing a compound of formula (I), R1 is H or C1-6alkyl; R2 is H or hydroxy; or pharmaceutically acceptable salt or diastereomer thereof, which is useful for prophylaxis and treatment of a viral disease in a patient relating to hepatitis B infection or a disease caused by hepatitis B infection.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: October 12, 2021
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Junli Chen, Manuel Konrath, Roland Meier, Yan Ren, Xuemei Wang, Jing Xiong, Jianhua Yu
  • Publication number: 20210283261
    Abstract: Heterobifunctional small molecules including anaplastic lymphoma kinase (ALK) ligand conjugated to a degradation/disruption tag through a linker, which selectively degrade/disrupt ALK, ALK fusion proteins, and/or ALK mutant proteins, and compositions and methods of using such degraders/disruptors to treat ALK-mediated cancer are provided.
    Type: Application
    Filed: December 4, 2018
    Publication date: September 16, 2021
    Inventors: Jian Jin, Yue Xiong, Jing Liu, Chengwei Zhang, Xiaoran Han, He Chen, Pu Wang
  • Publication number: 20210277049
    Abstract: The present invention relates to a cocrystal of progesterone, which is formed by the active ingredient progesterone and a cocrystal former which is selected from isophthalic acid, 4-formylbenzeneboronic acid and 3-nitrophthalic acid. The present invention also relates to the method for preparing the cocrystal of progesterone and use thereof for increasing the thickness of endometrium, improving progesterone's solubility or increasing progesterone's permeation rate.
    Type: Application
    Filed: March 4, 2021
    Publication date: September 9, 2021
    Inventors: Lan He, Jing Xiong, Xiangxiang Wu, Xin Zhu, Zhonglin Lu, Yan Shi, Na Zhang, Yang Liu
  • Patent number: 10940803
    Abstract: A simple vehicle rack includes: a fixing rod, a middle part of the fixing rod being an H-shaped reinforcing seat, the H-shaped reinforcing seat forming an upper sliding slot on a top surface of the fixing rod and forming a lower sliding slot on a bottom surface of the fixing rod; two fixing frames, the fixing frames being fixed on the top surface of the fixing rod and connected to the fixing rod, moving back and forth along the upper sliding slot; and two support frames, the support frames being fixed on the bottom surface of the fixing rod and connected to the fixing rod, moving back and forth along the lower sliding slot.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: March 9, 2021
    Assignee: FORCOME (ZHEJIANG) CO., LTD.
    Inventors: Xiaojun Ni, Chengsheng Fang, Jing Xiong, Jiancheng Wang
  • Publication number: 20200406826
    Abstract: A simple vehicle rack includes: a fixing rod, a middle part of the fixing rod being an H-shaped reinforcing seat, the H-shaped reinforcing seat forming an upper sliding slot on a top surface of the fixing rod and forming a lower sliding slot on a bottom surface of the fixing rod; two fixing frames, the fixing frames being fixed on the top surface of the fixing rod and connected to the fixing rod, moving back and forth along the upper sliding slot; and two support frames, the support frames being fixed on the bottom surface of the fixing rod and connected to the fixing rod, moving back and forth along the lower sliding slot.
    Type: Application
    Filed: February 3, 2020
    Publication date: December 31, 2020
    Inventors: Xiaojun NI, Chengsheng FANG, Jing XIONG, Jiancheng WANG
  • Publication number: 20200406827
    Abstract: A vehicle rack includes two cross beams, the cross beams being hollow square rods parallelly placed, the bottom center of the cross beam being provided with a sliding slot along the beams; two fixing rods, the fixing rods being hollow and each including an H-shaped reinforcing seat, the H-shaped reinforcing seat forming an upper sliding slot I on a top surface of the fixing rod and forming a lower sliding slot I on a bottom surface of the fixing rod, the fixing rods being particular to the two cross beams; a plurality of connecting seat, the connecting seats movably connecting the cross beams and the fixing rods, the connecting seats including upper bolt connecting parts; a plurality of supporting frames, the fixing rods each connecting two supporting frames, the supporting frames including lower bolt connecting parts.
    Type: Application
    Filed: February 3, 2020
    Publication date: December 31, 2020
    Inventors: Xiaojun NI, Chengsheng FANG, Jing XIONG, Jiancheng WANG
  • Publication number: 20200398764
    Abstract: A vehicle rack includes a cargo shelf, the cargo shelf including two beams and two fixing rods; four supporting frames, each beam being provided with two supporting frames that are movable along the beam, the two fixing rods being secured between two corresponding supporting frames on the two beams, a U-shaped plug interface being formed at the top of each supporting frame; a mobile frame that is movable along the beams and is U-shaped, the mobile frame including a horizontal rod and two vertical rods, a U-shaped plug interface I being formed at the top of each vertical rod; six connectors, each connector being provided with a clamping interface that opens through at bottom of the connector so that the connector can clamp the beam from top and then be inserted into the U-shaped plug interface or the U-shaped plug interface I; and six bolts.
    Type: Application
    Filed: February 3, 2020
    Publication date: December 24, 2020
    Inventors: Xiaojun NI, Chengsheng FANG, Jing XIONG, Jiancheng WANG
  • Publication number: 20200308178
    Abstract: The present invention relates to novel solid forms of compound (I), 3-[(8aS)-7-[[(4S)-5-ethoxycarbonyl-4-(3-fluoro-2-methyl-phenyl)-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]-3-oxo-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-2-yl]-2,2-dimethyl-propanoic acid and pharmaceutical compositions comprising solid forms thereof disclosed herein, which can be used as a HBV capsid inhibitor (or HBV Core Protein Allosteric Modifier), or for the treatment or prophylaxis of a viral disease in a patient relating to HBV infection or a disease caused by HBV infection.
    Type: Application
    Filed: March 24, 2020
    Publication date: October 1, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jing Xiong, Xuemei Wang
  • Publication number: 20200024287
    Abstract: The present invention relates to a process for synthesizing a compound of formula (I), R1 is H or C1-6alkyl; R2 is H or hydroxy; or pharmaceutically acceptable salt or diastereomer thereof, which is useful for prophylaxis and treatment of a viral disease in a patient relating to hepatitis B infection or a disease caused by hepatitis B infection.
    Type: Application
    Filed: January 4, 2018
    Publication date: January 23, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Junli CHEN, Manuel KONRATH, Roland MEIER, Yan REN, Xuemei WANG, Jing XIONG, Jianhua YU
  • Publication number: 20200024288
    Abstract: The present invention relates to novel solid forms of compound (I) [(1S)-1-[(2S,4R,5R)-5-(5-amino-2-oxo-thiazolo[4,5-d]pyrimidin-3-yl)-4-hydroxy-tetrahydrofuran-2-yl]propyl] acetate and pharmaceutical compositions comprising the solid forms thereof disclosed herein, which may be used as a TLR7 agonist, or for the treatment or prophylaxis of a viral disease in a patient relating to HBV infection or a disease caused by HBV infection.
    Type: Application
    Filed: January 4, 2018
    Publication date: January 23, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Katja GROSSE-SENDER, Urs SCHWITTER, Frank STOWASSER, Xuemei WANG, Jing XIONG
  • Patent number: 10507201
    Abstract: The present invention relates to therapeutic uses of compounds of formula (I) or a pharmaceutically acceptable salt thereof
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: December 17, 2019
    Assignee: NOVARTIS AG
    Inventors: Nicole Buschmann, Robin Alec Fairhurst, Pascal Furet, Diana Graus Porta, Carolina Haefliger, Bo Han, Thomas Knöpfel, Catherine Leblanc, Lv Liao, Robert Mah, Masato Murakami, Pierre Nimsgern, Michael Palmer, Dale Porter, Sebastien Ripoche, Can Wang, Youzhen Wang, Andreas Weiss, Jing Xiong, Xianglin Zhao
  • Patent number: 10463653
    Abstract: The present invention relates to therapeutic uses of compounds of formula (1) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: November 5, 2019
    Assignee: NOVARTIS AG
    Inventors: Lv Liao, Jing Xiong
  • Publication number: 20190231760
    Abstract: The present invention relates to therapeutic uses of compounds of formula (I) or a pharmaceutically acceptable salt thereof
    Type: Application
    Filed: February 28, 2019
    Publication date: August 1, 2019
    Inventors: Nicole BUSCHMANN, Robin Alec FAIRHURST, Pascal FURET, Diana GRAUS PORTA, Carolina HAEFLIGER, Bo HAN, Thomas KNOPFEL, Catherine LEBLANC, Lv LIAO, Robert MAH, Masato MURAKAMI, Pierre NIMSGERN, Michael PALMER, Dale PORTER, Sebastien RIPOCHE, Can WANG, Youzhen WANG, Andreas WEISS, Jing XIONG, Xianglin ZHAO
  • Publication number: 20190076412
    Abstract: The present invention relates to therapeutic uses of compounds of formula (1) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 13, 2018
    Publication date: March 14, 2019
    Inventors: Nicole BUSCHMANN, Robin Alec FAIRHURST, Pascal FURET, Thomas KNÖPFEL, Catherine LEBLANC, Lv LIAO, Robert MAH, Pierre NIMSGERN, Sebastien RIPOCHE, Jing XIONG, Bo HAN, Can WANG, Xianglin ZHAO
  • Patent number: 10130629
    Abstract: A pharmaceutical combination comprising N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, or a pharmaceutically acceptable salt thereof, and at least one active ingredient, as defined herein, or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: November 20, 2018
    Assignee: Novartis AG
    Inventors: Nicole Buschmann, Robin Alec Fairhurst, Jorge Garcia Fortanet, Pascal Furet, Diana Graus Porta, Nafeeza Hafeez, Bo Han, Thomas Knoepfel, Matthew J. LaMarche, Catherine Leblanc, Lv Liao, Robert Mah, Dale Porter, Can Wang, Markus Wartmann, Jing Xiong, Xianglin Zhao
  • Publication number: 20180185341
    Abstract: The present invention relates to therapeutic uses of compounds of formula (I) or a pharmaceutically acceptable salt thereof
    Type: Application
    Filed: October 2, 2015
    Publication date: July 5, 2018
    Inventors: Nicole BUSCHMANN, Robin Alec FAIRHURST, Pascal FURET, Diana GRAUS PORTA, Carolina HAEFLIGER, Bo HAN, Thomas KNÖPFEL, Catherine LEBLANC, Lv LIAO, Robert MAH, Masato MURAKAMI, Pierre NIMSGERN, Michael PALMER, Dale PORTER, Sebastien RIPOCHE, Can WANG, Youzhen WANG, Andreas WEISS, Jing XIONG, Xianglin ZHAO
  • Patent number: 9896449
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: February 20, 2018
    Assignee: Novartis AG
    Inventors: Nicole Buschmann, Robin Alec Fairhurst, Pascal Furet, Thomas Knöpfel, Catherine Leblanc, Lv Liao, Robert Mah, Pierre Nimsgern, Sebastien Ripoche, Jing Xiong, Bo Han, Can Wang, Xianglin Zhao