Abstract: The application provides a display substrate, a method for manufacturing the same, and a display device. The display substrate includes a display region and a binding region located at a periphery of the display region. The binding region is provided with a drive circuit pin and a flexible circuit board pin, and a connecting trace for connecting the drive circuit pin and the flexible circuit board pin. The connecting trace includes a first connecting line and a second connecting line connected in parallel, the first connecting line and the second connecting line are in different layers, the first connecting line is between an interlayer insulating layer and a base substrate of the display substrate, the first connecting line and the interlayer insulating layer are separated by a first insulating layer, and the second connecting line is on a side of the interlayer insulating layer away from the base substrate.

Abstract: The present disclosure discloses a method for automatically identifying south troughs by improved Laplace and relates to the technical field of meteorology. The method includes the following steps: acquiring grid data of a geopotential height field; calculating a gradient field of the geopotential height field in an x direction; searching for a turning point where a gradient value turned from being negative to being positive, and cleaning the gradient field; calculating a divergence of the x direction to obtain an improved Laplacian numerical value L?; performing 0,1 binarization processing on the L? to obtain a black-and-white image and a plurality of targets of potential troughs, merging the black-and-white image and the plurality of targets of the potential troughs by expansion, recovering original scale through erosion, and selecting an effective target through an angle of direction of a contour and an axial ratio.

Abstract: A lamination film structure including a combination of: (a) at least one first layer of an oriented polyethylene film and (b) at least one second layer of a blown or cast polyethylene film, wherein the first oriented polyethylene film layer is laminated with the second blown or cast polyethylene film layer; and wherein the blown or cast polyethylene film of component (b) is a blown polyethylene film or a cast polyethylene film comprising a formulated resin including a combination or mixture of: (bi) a predetermined amount of a post-consumer recycled resin sourced from a recycled high density polyethylene resin; and (bii) a predetermined amount of a polyethylene resin; a process for making the above lamination film structure; and a film or article made from a recyclate of the above lamination film structure.

Abstract: An apparatus to facilitate optimization of a convolutional neural network (CNN) is disclosed. The apparatus includes optimization logic to receive a CNN model having a list of instructions and including pruning logic to optimize the list of instructions by eliminating branches in the list of instructions that comprise a weight value of 0.

Abstract: In one embodiment, a method of building an optimized color flow high parameter reagent and reagent kit cytometry panel for detection of aberrant cells in acute myeloid leukemia is disclosed using a spectral flow cytometer with a least three excitation lasers and thirty-eight color detectors. In another embodiment, a graphical user interface is disclosed generated by a server computer from a fluorochrome database and displayed by a client computer to assist in the selection of a set of fluorochromes for use in an assay to analyze biological samples. The GUI can display spectra graphs to visually show how fluorochromes may overlap and can generate similarity indexes for the paired fluorochrome interference and a complexity index for overall many to many interferences generated by a selected group or set of fluorochromes.

Abstract: In one embodiment, a method of building an optimized color flow cytometry panel is disclosed using a full spectrum flow cytometer with five excitation lasers and five corresponding detection modules. In another embodiment, a graphical user interface is disclosed generated by a server computer from a fluorochrome database and displayed by a client computer to assist in the selection of a set of fluorochromes for use in an assay to analyze biological samples. The GUI can display spectra graphs to visually show how fluorochromes may overlap and can generate similarity indexes for the paired fluorochrome interference and a complexity index for overall many to many interferences generated by a selected group or set of fluorochromes.

Abstract: An anionic hydrogel for wound healing comprised of poly(oligoethylene glycol monoacrylate), acrylic, a neutral species and a wild-type fibroblast growth factor 1 (wtFGF1).

Abstract: In an aspect, a method of making a composite core-shell nanoparticle comprises forming a nanoparticle core comprising nickel oxide or iron oxide via thermal decomposition of a nickel complex or an iron complex; and forming an oxide shell over the core, the oxide shell comprising nickel, iron or a mixture thereof. In another aspect, a method of making composite nanoparticles comprises providing a mixture comprising nickel complex and iron complex; and thermally decomposing the nickel and iron complexes to provide the composite nanoparticles comprising (Ni,Fe)Ox alloy. In yet another aspect, a composition comprises composite nanoparticles, the composite nanoparticles including a nickel oxide core and oxide shell, the oxide shell comprising a mixture of nickel and iron.

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

Abstract: An anionic hydrogel based on poly(acrylic acid)-co-poly(oligoethylene glycol monoacrylate) (PAA-co-POEGA) for protein delivery and method of making the same.

Abstract: Systems and methods described herein provide auto-scaling of virtual delivery agent services. The system can identify data indicating consumption of a pool of active virtual delivery agents over a plurality of previous time frames. The system can determine a usage metric for a time frame of the plurality of previous time frames based on the data indicating consumption of the pool of active virtual delivery agents. The system can control, responsive to an auto-scale setting of the pool based on the usage metric, a number of active virtual delivery agents in the pool for a future time frame that corresponds to the time frame of the plurality of previous time frames.

Abstract: In one aspect, nanoparticles for ethanol oxidation are described herein, which comprise a core including at least one Group IB metal and a shell disposed over the core, wherein the shell comprises islands of alloyed platinum group metals. In another aspect, an electrode is described herein, which in some embodiments, comprises a substrate and electrocatalytic nanoparticles deposited over the substrate. In some embodiments, the electrode described herein further comprises a layer of carbon nanoparticles positioned between the substrate and the electrocatalytic nanoparticles. In yet another aspect, a method of ethanol oxidation is described herein. In some embodiments, such a method comprises (i) providing an electrode comprising a substrate and electrocatalytic nanoparticles deposited over the substrate, (ii) disposing the electrode in an alkaline medium comprising ethanol; and (iii) oxidizing the ethanol with the electrode.

Abstract: In an aspect, a method of making a composite core-shell nanoparticle comprises forming a nanoparticle core comprising nickel oxide or iron oxide via thermal decomposition of a nickel complex or an iron complex; and forming an oxide shell over the core, the oxide shell comprising nickel, iron or a mixture thereof. In another aspect, a method of making composite nanoparticles comprises providing a mixture comprising nickel complex and iron complex; and thermally decomposing the nickel and iron complexes to provide the composite nanoparticles comprising (Ni,Fe)Ox alloy. In yet another aspect, a composition comprises composite nanoparticles, the composite nanoparticles including a nickel oxide core and oxide shell, the oxide shell comprising a mixture of nickel and iron.

Abstract: An anionic hydrogel based on poly(acrylic acid)-co-poly(oligoethylene glycol monoacrylate) (PAA-co-POEGA) for protein delivery and method of making the same.

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

Abstract: In one aspect, compositions comprising copper-silica (Cu—SiO2) core-shell nanoparticles are described herein. The core-shell nanoparticles comprise copper (Cu) core components and silica (SiO2) shell components encapsulating the core components. In some embodiments, the nanoparticle compositions comprise a continuous aqueous phase and a population of copper-silica (Cu—SiO2) core-shell nanoparticles dispersed in the aqueous phase.

Abstract: A composition and methods for the non-invasive destruction of bacteria cells in vivo using a combination therapy of antibiotics and photothermal nano-theranostics. In one aspect, a composition and method for destroying at least one bacteria cell using a functionalized PA contrast agent with a targeting agent, coating, and antibiotic that uses photoacoustic signals to create thermal energy and release the loaded antibiotic are described.

Abstract: A method for synthesizing noble metal nanostructures is disclosed. The method involves reacting under heat a noble metal precursor, a polyol reducing agent, and a stabilizing polymer. Morphological control is achieved by controlling the reduction rate of the noble metal.

Abstract: The present invention includes a conjugates comprising a carbon nanotube with at least one covalently attached recognition module, and at least one covalently attached pharmaceutical compound or a precursor of the pharmaceutical compound, wherein the pharmaceutical compound, or precursor of the pharmaceutical compound, is attached to the carbon nanotube by a linker moiety.