Abstract: A patient interface including a plenum chamber, a first seal-forming structure for forming a seal around the patient's mouth, and a second seal-forming structure for forming a seal around the patient's nares. The patient interface further includes at least one stopper rib disposed in the cavity of the plenum chamber spaced apart from the first seal-forming structure in a rest position. The first seal-forming structure configured to contact the at least one stopper rib in an operational position. The at least one stopper rib configured to oppose compression of the first seal-forming structure in an anterior direction. The second seal-forming structure is not configured to contact the at least one stopper rib.

Abstract: The embodiments of the present disclosure provide a method for positioning a target object. The method may include: determining an identification result by processing an image based on an identification model, wherein the identification result includes a first position of each of at least one target object in a first coordinate system; determining, from the image, a target image of each of the at least one target object based on the first position of each of the at least one target object in the first coordinate system; and determining, based on a first reference image and the target image of each of the at least one target object, a second position of each of the at least one target object in a second coordinate system, wherein the second position is configured to determine operation parameters of an operating device.

Abstract: The present invention discloses a stereo garage that comprises: a main body provided with a lifting shaft, wherein the lifting shaft is provided with an opening; a lifting platform located in the lifting shaft, wherein the lifting platform can ascend or descend in the lifting shaft along a height direction of the main body, such that the lifting platform can switch between an initial position and an end position, wherein the lifting platform can close the opening when the lifting platform is located in the initial position; an anti-falling device connected to the main body, wherein the anti-falling device comprises a blocking rod which can be switched between a locking position and an unlocking position; wherein, the blocking rod can block a movement of a vehicle when the blocking rod is located in the locking position, and the lifting platform can cause the blocking rod to be switched from the locking position to the unlocking position when the lifting platform comes into the initial position.

Abstract: A method for testing burning performance of a dark-colored cigarette using a dark-colored cigarette paper is provided. The dark-colored cigarette paper has a grayscale less than 255. The method includes: simulating, by a robotic arm, a cigarette smoking process and environment; acquiring, by a full-vision camera system, an image of a burn line and ash column region of the dark-colored cigarette; and analyzing a burning performance indicator of the dark-colored cigarette according to coordinate information of the burn line and ash column region. The method is based on a surface reflection characteristic of the dark-colored cigarette paper and a principle of optical reflection to light and highlight an edge of the dark-colored cigarette sample by a light source at a certain angle from a side. In this way, the method forms a chromatic aberration to localize the dark-colored cigarette sample, thereby testing the burning performance of the dark-colored cigarette sample.

Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.

Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.

Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.

Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.

Abstract: A method, including: identifying static application features of an application; identifying resource access features of the application; labeling a translation lookaside buffer (TLB) miss threshold of a runtime feature of the application; determining utilization of larger pages during the runtime based on the TLB miss threshold; and setting the TLB miss threshold based on the determined utilization of the larger pages.

Abstract: Provided are a surface zwitterionized silicone antifouling coating and a preparation method thereof. In the disclosure, hydroxyl-terminated polydimethylsiloxane and N-aminoethyl-3-aminopropyl methyl dimethoxysilane are used as raw materials, and tetramethylammonium hydroxide pentahydrate is used as a catalyst, thereby preparing a series of polydimethylsiloxane resins containing amino side chains in different proportions; then side chain amino modified polydimethylsiloxane is crosslinked and cured by using 3-glycidyloxypropyltrimethoxysilane as a curing agent; after that, the cured silicone coating is soaked in a solution of 1,3-propane sultone in acetone for ionization.

Abstract: Provided in the embodiments of the present disclosure are a display panel, a display apparatus and a driving method therefor, and an image rendering method.

Abstract: A device for photo alignment includes: a bearing platform; a linearly polarized light source located at one side of the bearing platform; and a control assembly located between the linearly polarized light source and the bearing platform. One side of the bearing platform close to the control assembly is configured for placing a large plate glass to be aligned, and the large plate glass to be aligned includes a plurality of alignment areas; the linearly polarized light source is configured for providing a first polarized light to the control assembly; the control assembly is configured for adjusting a polarization direction of the first polarized light, and configured for providing a second polarized light to the plurality of alignment areas included in the large plate glass to be aligned; and polarization directions of the second polarized light respectively corresponding to at least two alignment areas are different.

Abstract: The present invention provides a keratin BD-3, a nucleic acid molecule encoding same, an expression vector, a host cell, a preparation method therefor, and a pharmaceutical composition contained the keratin BD-3. The keratin BD-3 can be used in the preparation of medicament for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.

Abstract: An aza-ergoline derivative and a preparation method therefor and an application thereof. The derivative has a structure as shown in formula (I). The aza-ergoline derivative has good affinity, agonistic activity or selectivity to a dopamine D2 receptor.

Abstract: The present disclosure provides a method for preparing lithium iron phosphate from ferric hydroxyphosphate, including: purifying ferrous sulfate to form a ferrous sulfate solution, adding hydrogen peroxide, phosphoric acid, an ammonium dihydrogen phosphate solution and ammonia water into the ferrous sulfate solution and then reacting to form a mixed slurry, holding the mixed slurry at a temperature for a period of time, and then washing with water and subjecting to press filtration to form ferric hydroxyphosphate precursors with different iron-phosphorus ratios; then flash drying, sintering at a high temperature, and pulverizing to obtain ferric hydroxyphosphate precursors with different iron-phosphorus ratios and different specific surface areas.

Abstract: A wearable device includes a frame element and a dielectric substrate. The frame element includes a first metal element, a second metal element, and a third metal element. A first gap is provided between the first metal element and the second metal element. A second gap is provided between the second metal element and the third metal element. A third gap is provided between the third metal element and the first metal element. The dielectric substrate is surrounded by the first metal element, the second metal element, and the third metal element. A first antenna element is formed by the first metal element. A second antenna element is formed by the second metal element. A third antenna element is formed by the third metal element.

Abstract: A display panel, a gate drive circuit, a shift register unit and a driving method thereof. The shift register unit includes: a shift register (1) connected with a signal input end (CR) and a signal output end (OUT), configured to control an electric potential of the signal output end (OUT) under control of an electric potential of the signal input end (CR); a control circuit (2) connected with a start signal end (STV), a control signal end (EN) and the signal input end (CR), configured to control the start signal end (STV) to connect to the signal input end (CR) under control of an electric potential of the control signal end (EN). The present disclosure can achieve independent refreshing of any area on the display panel.

Abstract: The present disclosure relates to a texture sampling method and apparatus based on merge processing of texel requests. The present disclosure merges target texel requests in the same cache line together, which reduces the number of cache hit tests. A pressure on the cache of next level to process texel requests may be significantly reduced, and the speed of texture sampling may be increased. The method includes: creating a texture sampling request, where the texture sampling request includes a pixel to be processed; obtaining multiple target texel requests based on pixel coordinates of the pixel to be processed; performing a merge processing on the multiple target texel requests according to a preset rule, and obtaining a merge table of texel requests; sequentially performing cache hit tests on the multiple target texel requests to obtain target texels based on the valid cache lines in the merge table of texel requests.

Abstract: A transistor, a 3D memory and a manufacturing method therefor, and an electronic device are provided in the present application. The 3D memory includes a plurality of layers of memory cells stacked in a direction perpendicular to a substrate, and a word line. A memory cell includes a transistor which includes a source and a drain, a gate extending in the direction perpendicular to the substrate, a semiconductor layer surrounding a sidewall of the gate. The semiconductor layer includes a source contact region and a drain contact region arranged at intervals. A channel between the source contact region and the drain contact region is a horizontal channel, and the word line extends in the direction perpendicular to the substrate and penetrates through the memory cells of different layers.

Abstract: A method for evaluating a downhole working condition of a PDC bit includes: performing an indoor test, including performing a drilling test in different full-sized cores by using the PDC bit with different degrees of abrasion and balling under condition of given WOB and rotational speed, to acquire change characteristics of a WOB, a rotational speed, a torque, a ROP and a bit vibration of the PDC bit in different time domains; improving and perfecting an existing prediction model and evaluation method for the downhole working condition through data obtained by the test to obtain the method; reading parameters of the WOB, the rotational speed, the torque and the ROP in real time during drilling; determining the downhole working condition of the PDC bit by using the method in the improving and perfecting.